神経論文 

合計:247

論文名サンプル色素イメージングシステム
Structural and functional connectivity from the dorsomedial hypothalamus to the ventral medulla as a chronological amplifier of sympathetic outflow.

Yosuke Kono, Shigefumi Yokota, Isato Fukushi, Yosuke Arima, Hiroshi Onimaru, Shuntaro Okazaki, Kotaro Takeda, Itaru Yazawa, Masashi Yoshizawa, Yohei Hasebe, Keiichi Koizumi, Mieczyslaw Pokorski, Takako Toda, Kanji Sugita & Yasumasa Okada

Scientific Reports volume 10, Article number: 13325 (2020).
Brainstem-spinal cordVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Voltage Imaging of Cortical Oscillations in Layer 1 with Two-Photon Microscopy.

Neil Dalphin, Kevin Dorgans, Eugene Khaskin, and Bernd Kuhn

eNeuro. 2020 May-Jun; 7(3): ENEURO.0274-19.2020.
HEK293VSD
(di1-ANNINE-6plus and di4-ANNINE-6plus)
MiCAM03-N256
Differential cortical and subcortical projection targets of subfields in the core region of mouse auditory cortex.

Shiro Nakata, Makoto Takemoto, Wen-Jie Song

Hear Res. 2020 Feb;386:107876.
In Vivo
(auditory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Postnatal development of subfields in the core region of the mouse auditory cortex.

Feifan Chen, Makoto Takemoto, Masataka Nishimura, Ryohei Tomioka, Wen-Jie Song

Hear Res. 2021 Feb;400:108138.
In Vivo
(auditory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Spatiotemporal properties of whisker-evoked tactile responses in the mouse secondary somatosensory cortex.

Sophie Hubatz, Guillaume Hucher, Daniel E. Shulz & Isabelle Férézou

Scientific Reports volume 10, Article number: 763 (2020)
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Neuronal Encoding of Multisensory Motion Features in the Rat Associative Parietal Cortex.

Jeanne Caron-Guyon, Julien Corbo, Yoh'i Zennou-Azogui, Christian Xerri, Anne Kavounoudias, Nicolas Catz

Cereb Cortex. 2020 Sep 3;30(10):5372-5386.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus.

Thomas T. Luyben, Jayant Rai, Hang Li, John Georgiou, Ariel Avila, Mei Zhen, Graham L. Collingridge, Takashi Tominaga, and Kenichi Okamoto

Front Neural Circuits. 2020; 14: 24.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Cellular-resolution mapping uncovers spatial adaptive filtering at the rat cerebellum input stage.

Stefano Casali, Marialuisa Tognolina, Daniela Gandolfi, Jonathan Mapelli & Egidio DfAngelo

Communications Biology volume 3, Article number: 635 (2020)
Slice
(cerebellum)
CaSD
(Fura-2 AM)

VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Alleviating toxic α-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinsonfs disease.

Alysia Ross, Viktoria Xing, Ting Ting Wang, Samantha C. Bureau, Giovana A. Link, Teresa Fortin, Hui Zhang, Shawn Hayley & Hongyu Sun

Molecular Brain volume 13, Article number: 108 (2020)
Cell culture
(SH-SY5Y cells)
VSD
(Di-4-ANEPPS)
MiCAM05-N256
Electrophysiological Characterization of Networks and Single Cells in the Hippocampal Region of a Transgenic Rat Model of Alzheimerfs Disease.

Ingrid Heggland, Pål Kvello, and Menno P. Witter

eNeuro. 2019 Jan-Feb; 6(1): ENEURO.0448-17.2019.
Slice
(medial entorhinal cortex)
VSD
(RH-795)
MiCAM ULTIMA
Local network determinants of spontaneously emerging cortical maps.

Tomer Fekete, David B. Omer, Amiram Grinvald, Cees van Leeuwen

bioRxiv, 764068
In Vivo
(visual cortex)
VSD
(RH-1916)
MiCAM ULTIMA
Dynamic Patterns of Spontaneous Ongoing Activity in the Visual Cortex of Anesthetized and Awake Monkeys are Different.

David B Omer, Tomer Fekete, Yigal Ulchin, Rina Hildesheim, Amiram Grinvald

Cereb Cortex. 2019 Mar 1;29(3):1291-1304.
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM ULTIMA
CRF Mediates Stress-Induced Pathophysiological High-Frequency Oscillations in Traumatic Brain Injury.

Chakravarthi Narla, Paul S. Jung, Francisco Bautista Cruz, Michelle Everest, Julio Martinez-Trujillo, and Michael O. Poulter

eNeuro. 2019 Mar-Apr; 6(2): ENEURO.0334-18.2019.
Slice
(piriform cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Wide-field Single-photon Optical Recording in Brain Slices Using Voltage-sensitive Dye.

Yoko Tominaga, Makiko Taketoshi, Naoko Maeda, Takashi Tominaga

J Vis Exp. 2019 Jun 20;(148).
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Network Plasticity Involved in the Spread of Neural Activity Within the Rhinal Cortices as Revealed by Voltage-Sensitive Dye Imaging in Mouse Brain Slices.

Riichi Kajiwara, Yoko Tominaga, and Takashi Tominaga

Front Cell Neurosci. 2019; 13: 20.
Slice
(rhinal cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Postnatal Development of Functional Projections from Parasubiculum and Presubiculum to Medial Entorhinal Cortex in the Rat.

Cathrin B. Canto, Noriko Koganezawa, Mariá José Lagartos-Donate, Kally C. O'Reilly, Huibert D. Mansvelder, and Menno P. Witter

J Neurosci. 2019 Oct 30;39(44):8645-8663.
Slice
(medial entorhinal cortex)
VSD
(RH-795)
MiCAM ULTIMA
Large Scale Calcium Imaging of the Cerebellar Vermis During Sensory Stimulus Unravels Two Responsefs Components That Differ in Their Spatiotemporal Properties.

Hananel Byk, Guo-Jen Huang, Yoichiro Iwakura, Yosef Yarom

Front Syst Neurosci. 2019; 13: 18.
In Vivo
(cerebellar cortex)
CaSD
(Oregon Green 488 Bapta-1)
MiCAM ULTIMA
Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits.

Morgane Sonia Thion, Coralie-Anne Mosser, Isabelle Férézou, Pauline Grisel, Sofia Baptista, Donovan Low, Florent Ginhoux, Sonia Garel, Etienne Audinat

Cell Rep. 2019 Jul 30; 28(5): 1119?1126.e4.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Overall Assay of Neuronal Signal Propagation Pattern With Long-Term Potentiation (LTP) in Hippocampal Slices From the CA1 Area With Fast Voltage-Sensitive Dye Imaging.

Yoko Tominaga, Makiko Taketoshi, and Takashi Tominaga

Front Cell Neurosci. 2018; 12: 389.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA or
MiCAM02
Organization of auditory areas in the superior temporal gyrus of marmoset monkeys revealed by real-time optical imaging.

Masataka Nishimura, Makoto Takemoto and Wen-Jie Song

Brain Struct Funct. 2018 May;223(4):1599-1614.
In Vivo
(auditory cortex)
VSD
(RH-795)
MiCAM ULTIMA
Dynamic Patterns of Spontaneous Ongoing Activity in the Visual Cortex of Anesthetized and Awake Monkeys are Different.

David B Omer, Tomer Fekete, Yigal Ulchin, Rina Hildesheim and Amiram Grinvald

Cereb Cortex. 2018 Apr 27.
In Vivo
(visual cortex)
VSD
(RH-1916)
MiCAM ULTIMA
Critical dynamics, anesthesia and information integration: Lessons from multi-scale criticality analysis of voltage imaging data.

Tomer Fekete, David B.Omer, Kazunori O'Hashi, Amiram Grinvald, Ceesvan Leeuwen and Oren Shriki

Neuroimage. 2018 Aug 16;183:919-933.
In Vivo
(cortex)
VSD
(RH-237, RH-2015, RH-1916)
MiCAM ULTIMA
Experimental tooth movement temporally changes neural excitation and topographical map in rat somatosensory cortex.

Mari Kaneko, Satoshi Fujita, Noriyoshi Shimizu, Mitsuru Motoyoshi and Masayuki Kobayashi

Brain Res. 2018 Nov 1;1698:62-69.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
Pain-Relieving Effects of mTOR Inhibitor in the Anterior Cingulate Cortex of Neuropathic Rats.

Sun Woo Um, Min Jee Kim, Joong Woo Leem, Sun Joon Bai and Bae Hwan Lee

Mol Neurobiol. 2018 Jul 22.
In Vivo
(cortex)
VSD
(Di-2-ANEPEQ)
MiCAM02
Involvement of thromboxane A2 in interleukin-31-induced itch-associated response in mice.

Tsugunobu Andoh, Sikai Li and Daisuke Uta

Pharmacol Rep. 2018 Apr;70(2):251-257.
Cell culture
(keratinocyte)
CaSD
(Fluo-3)
MiCAM02
Inhibitory effects of eugenol on putative nociceptive response in spinal cord preparation isolated from neonatal rats.

Saki Yagura, Hiroshi Onimaru, Koji Kanzaki and Masahiko Izumizaki

Exp Brain Res. 2018 Jun;236(6):1767-1774.
Spinal cordVSD
(Di-2-ANEPEQ)
MiCAM02
Confocal calcium imaging analysis of respiratory-related burst activity in the parafacial region.

Hiroshi Onimaru, Shiro Nakamura, Keiko Ikeda, Kiyoshi Kawakami and Tomio Inoue

Brain Res Bull. 2018 May;139:16-20.
Brainstem-spinal cordCaSD
(Fluo-8)
MiCAM02
Somatotopic Organization and Temporal Characteristics of Cerebrocortical Excitation in Response to Nasal Mucosa Stimulation With and Without an Odor in the Rat: An Optical Imaging Study.

Manabu Zama, Yaeko Hara, Satoshi Fujita, Tadayoshi Kaneko and Masayuki Kobayashi

Neuroscience. 2018 May 1;377:77-86.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
DCC Is Required for the Development of Nociceptive Topognosis in Mice and Humans.

Ronan V. da Silva, Helge C. Johannssen, Matthias T. Wyss, R. Brian Roome, Farin B. Bourojeni, Nicolas Stifani, Ashley P.L. Marsh, Monique M. Ryan, Paul J. Lockhart, Richard J. Leventer, Linda J. Richards, Bernard Rosenblatt, Myriam Srour, Bruno Weber, Hanns Ulrich Zeilhofer and Artur Kania

Cell Rep. 2018 Jan 30;22(5):1105-1114.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex.

María Eugenia Vilarchao, Luc Estebanez, Daniel E. Shulz and Isabelle Férézou

Cell Rep. 2018 Mar 27;22(13):3534-3547.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Opposing and Complementary Topographic Connectivity Gradients Revealed by Quantitative Analysis of Canonical and Noncanonical Hippocampal CA1 Inputs.

Yanjun Sun, Douglas A. Nitz, Todd C. Holmes, and Xiangmin Xu

eNeuro. 2018 Jan 30;5(1).
Slice
(hippocampus)
VSD
(NK3630/RH-482)
MiCAM02
Focal brain lesions induced with ultraviolet irradiation.

Mariko Nakata, Kazuaki Nagasaka, Masayuki Shimoda, Ichiro Takashima and Shinya Yamamoto

Scientific Reportsvolume 8, Article number: 7968 (2018)
In Vivo
(cortex)
VSD
(RH-795)
MiCAM01
Fast Voltage-Sensitive Dye Imaging of Excitatory and Inhibitory Synaptic Transmission in the Rat Granular Retrosplenial Cortex.

Ken'ichi Nixima, Kazuo Okanoya, Noritaka Ichinohe and Tohru Kurotani

J Neurophysiol. 2017 Jul 12:jn.00734.2016.
Slice
(cortex)
VSD
(Di-4-ANEPPS)
MiCAM02
Activation of the CREB/c-Fos Pathway during Long-Term Synaptic Plasticity in the Cerebellum Granular Layer.

Daniela Gandolfi, Silvia Cerri, Jonathan Mapelli, Mariarosa Polimeni, Simona Tritto, Marie-Therese Fuzzati-Armentero, Albertino Bigiani, Fabio Blandini, Lisa Mapelli, and Egidio DfAngelo

Front Cell Neurosci. 2017; 11: 184.
Slice
(cerebellum)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

Petr Unichenko, Jenq-Wei Yang, Sergei Kirischuk, Sergei Kolbaev, Werner Kilb, Matthieu Hammer, Dilja Krueger-Burg, Nils Brose, and Heiko J. Luhmann

Cerebral Cortex, 2017; 1?14
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Topographical projections from the nucleus basalis magnocellularis (Meynert) to the frontal cortex: A voltage-sensitive dye imaging study in rats.

Kazuaki Nagasaka, Yumiko Watanabe, and Ichiro Takashima

Brain Stimul. 2017 Jul 3. pii: S1935-861X(17)30840-9. doi: 10.1016/j.brs.2017.06.008. [Epub ahead of print]
In Vivo
(frontal cortex)
VSD
(RH-795)
MiCAM01
Behavioral consequences of a bifacial map in the mouse somatosensory cortex.

Vassiliy Tsytsarev, Hiroyuki Arakawa, Shuxin Zhao, Alain Chédotal and Reha S. Erzurumlu

Journal of Neuroscience 29 June 2017, 0598-17
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM02
Effects of experimental traumatic brain injury and impaired glutamate transport on cortical spreading depression.

Mahshid Sadat Hosseini-Zare, Feng Gu, Ahmad Abdulla, Simon Powell, and Jokūbas Žiburkus

Exp Neurol. 2017 Sep;295:155-161. doi: 10.1016/j.expneurol.2017.05.002. Epub 2017 May 4.
Slice
(visual cortex)
VSD
(Di-4-ANEPPS)
MiCAM02
Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury.

Minjee Kwon, Jeongsoo Han, Un Jeng Kim, Myeounghoon Cha, Sun Woo Um, Sun Joon Bai, Seong-Karp Hong, and Bae Hwan Lee

Front Mol Neurosci. 2017; 10: 79. Published online 2017 Mar 21. doi: 10.3389/fnmol.2017.00079
In Vivo
(cortex)
VSD
(Di-2 ANEPEQ)
MiCAM02
Spatiotemporal changes of optical signals in the somatosensory cortex of neuropathic rats after electroacupuncture stimulation.

Myeounghoon Cha, Younbyoung Chae, Sun Joon Bai, and Bae Hwan Lee

BMC Complement Altern Med. 2017; 17: 33. Published online 2017 Jan 10. doi: 10.1186/s12906-016-1510-5
In Vivo
(somatosensory cortex)
VSD
(Di-2 ANEPEQ)
MiCAM02
Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus.

Vincenzo Micale, Jens Stepan, Angela Jurik, Fabricio A. Pamplona, Rudolph Marsch, Filippo Drago, Matthias Eder and Carsten T. Wotjak

J Psychiatr Res. 2017 Jul;90:46-59. doi: 10.1016/j.jpsychires.2017.02.002. Epub 2017 Feb 3.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Intracortical signal processing of periodontal ligament sensations in rat.

Aoi Minoda, Naoko Mizoguchi, Masayuki Kobayashi, Naoto Suda, Kazuyo Muramoto

Neuroscience. 2017 Jul 4;355:212-224. doi: 10.1016/j.neuroscience.2017.04.045. Epub 2017 May 10.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM02
Optical Imaging of the Motor Cortex Following Antidromic Activation of the Corticospinal Tract after Spinal Cord Injury.

Kyung H. Lee, Un J. Kim, Se W. Park, Yong G. Park, and Bae H. Lee

Front Neurosci. 2017; 11: 166.
In Vivo
(motor cortex)
VSD
(Di-2 ANEPEQ)
MiCAM02
Novel trigeminal slice preparation method for studying mechanisms of nociception transmission.

Mikiko Hirahara, Naoshi Fujiwara, Kenji Seo

J Neurosci Methods. 2017 Jul 15;286:6-15. doi: 10.1016/j.jneumeth.2017.05.019. Epub 2017 May 15.
Slice
(brainstem)
CaSD
(Rhod-2)
MiCAM02
Local and Long-Range Circuit Connections to Hilar Mossy Cells in the Dentate Gyrus.

Yanjun Sun, Steven F. Grieco, Todd C. Holmes and Xiangmin Xu

eNeuro. 2017 Apr 19;4(2). pii: ENEURO.0097-17.2017. doi: 10.1523/ENEURO.0097-17.2017. eCollection 2017 Mar-Apr.
Slice
(hippocampus)
VSD
(NK3630/RH-482)
MiCAM02
Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (AƒÀ) in murine models of Alzheimer's disease (AD).

Gerhard Rammes, Corinna Mattusch, Matthias Wulff, Franziska Seeser, Matthias Kreuzer, Kaichuan Zhu, Jan M. Deussing, Jochen Herms, Chris G. Parsons

Neuropharmacology. 2017 Feb 4;123:100-115. doi: 10.1016/j.neuropharm.2017.02.003. [Epub ahead of print]
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Spatiotemporal Profiles of Proprioception Processed by the Masseter Muscle Spindles in Rat Cerebral Cortex: An Optical Imaging Study.

Satoshi Fujita, Mari Kaneko, Hiroko Nakamura, and Masayuki Kobayashi

Front Neural Circuits. 2017; 11: 4.
In Vivo
(insular cortex)
VSD
(RH-1691)
MiCAM02
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain.

Kassandra Kisler, Amy R Nelson, Sanket V Rege, Anita Ramanathan, Yaoming Wang, Ashim Ahuja, Divna Lazic, Philbert S Tsai, Zhen Zhao, Yi Zhou, David A Boas, Sava Sakadžić & Berislav V Zlokovic

Nat Neurosci. 2017 Jan 30. doi: 10.1038/nn.4489.
In Vivo
(somatosensory cortex)
VSD
(RH-1692)
MiCAM02
Effects of a TRPV1 agonist capsaicin on respiratory rhythm generation in brainstem-spinal cord preparation from newborn rats.

Mariho Tani, Sayumi Kotani, Chikara Hayakawa, Shih-Tien Lin, Saki Irie, Keiko Ikeda, Kiyoshi Kawakami and Hiroshi Onimaru

Pflugers Arch. 2017 Feb;469(2):327-338. doi: 10.1007/s00424-016-1912-8. Epub 2016 Nov 29.
Brainstem-spinal cordVSD
(Di-2-ANEPEQ)
MiCAM02
Interaction between novel oscillation within the ventromedial hypothalamus and the sympathetic nervous system.

Kamon Iigaya, Shuntaro Okazaki, Yoshino Minoura and Hiroshi Onimaru

Neuroscience. 2017 Feb 20;343:213-221. doi: 10.1016/j.neuroscience.2016.11.048. Epub 2016 Dec 10.
Slice
(hippothalamus)
VSD
(Di-2-ANEPEQ)
MiCAM02
Paired Burst Stimulation Causes GABAA Receptor-Dependent Spike Firing Facilitation in CA1 of Rat Hippocampal Slices.

Takashi Tominaga and Yoko Tominaga

Front Cell Neurosci. 2016 Jan 29;10:9. doi: 10.3389/fncel.2016.00009. eCollection 2016.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01 and
MiCAM ULTIMA
Voltage-sensitive dye imaging of mouse neocortex during a whisker detection task.

Alexandros Kyriakatos, Vijay Sadashivaiah, Yifei Zhang, Alessandro Motta, Matthieu Auffret and Carl C. H. Petersen

Neurophotonics. 2016 Jul;4(3):031204. Epub 2016 Nov 23.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Parallel pathways from whisker and visual sensory cortices to distinct frontal regions of mouse neocortex.

Varun Sreenivasan, Alexandros Kyriakatos, Celine Mateo, Dieter Jaeger and Carl C.H. Petersen.

Neurophotonics. 2016 Jul;4(3):031203. Epub 2016 Nov 23.
In Vivo
(sensorimotor cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Review of imaging network activities in developing rodent cerebral cortex in vivo.

Luhmann HJ

Neurophotonics. 2017 Jul;4(3):031202. Epub 2016 Nov 23.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Population Response Propagation to Extrastriate Areas Evoked by Intracortical Electrical Stimulation in V1.

Tamás D. Fehérvári and Tetsuya Yagi

CFront Neural Circuits. 2016 Feb 12;10:6. doi: 10.3389/fncir.2016.00006. eCollection 2016.
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Uncovering the Spatial Profile of Contour Integration from Fixational Saccades: Evidence for Widespread Processing in V1.

Ariel Gilad, Roy Oz and Hamutal Slovin

Cereb. Cortex (2016) doi: 10.1093/cercor/bhw305 First published online: October 6, 2016
In Vivo
(visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Pathophysiological implication of CaV3.1 T-type Ca2+ channels in trigeminal neuropathic pain

Soonwook Choi, Eunah Yu, Eunjin Hwang, and Rodolfo R. Llinás

Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2270?2275. Published online 2016 Feb 8. doi: 10.1073/pnas.1600418113
In Vivo
(somatosensory cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
The decline in synaptic GluN2B and rise in inhibitory neurotransmission determine the end of a critical period.

Noriko Isoo, Takae Ohno, Mutsumi Isowaki, Satoshi Fukuda, Naoyuki Murabe, Hiroaki Mizukami, Keiya Ozawa, Masayoshi Mishina, and Masaki Sakurai

Sci Rep. 2016; 6: 34196. Published online 2016 Sep 28. doi: 10.1038/srep34196
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM02
In vivo voltage-sensitive dye imaging of the insular cortex in nerve-injured rats.

Jeongsoo Han, Myeounghoon Cha, Minjee Kwon, Seong-Karp Hong, Sun Joon Bai, Bae Hwan Lee

Neurosci Lett. 2016 Nov 10;634:146-152. doi: 10.1016/j.neulet.2016.10.015. Epub 2016 Oct 11.
In Vivo
(insular cortex)
VSD
(Di-2-ANEPEQ)
MiCAM02
A role of CB1R in inducing θ-rhythm coordination between the gustatory and gastrointestinal insula

Youngnam Kang, Hajime Sato, Mitsuru Saito, Dong Xu Yin, Sook Kyung Park, Seog Bae Oh, Yong Chul Bae, and Hiroki Toyoda

Sci Rep. 2016 Sep 1;6:32529. doi: 10.1038/srep32529.
Slice
(insular cortex)
VSD
(RH-414)
MiCAM02
3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice.

Yaoming Wang, Zhen Zhao, Sanket V Rege, Min Wang, Gabriel Si, Yi Zhou, Su Wang, John H Griffin, Steven A Goldman and Berislav V Zlokovic

Nat Med. 2016 Sep;22(9):1050-5. doi: 10.1038/nm.4154. Epub 2016 Aug 22.
In Vivo
(cortex)
VSD
(RH-1692)
MiCAM02
Layer-specific potentiation of network GABAergic inhibition in the CA1 area of the hippocampus.

Michelangelo Colavita, Geoffrey Terral, Clement E. Lemercier, Filippo Drago, Giovanni Marsicano, and Federico Massa

Sci Rep. 2016 Jun 27;6:28454. doi: 10.1038/srep28454.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
The Site of Spontaneous Ectopic Spike Initiation Facilitates Signal Integration in a Sensory Neuron.

Carola Städele and Wolfgang Stein

J Neurosci. 2016 Jun 22;36(25):6718-31. doi: 10.1523/JNEUROSCI.2753-15.2016.
Stomatogastric ganglionVSD
(Di-4-ANEPPS or Di-4-ANNEPDHQ)
MiCAM02
In Vivo Mesoscopic Voltage-Sensitive Dye Imaging of Brain Activation.

Qinggong Tang, Vassiliy Tsytsarev, Aaron Frank, Yalun Wu, Chao-wei Chen, Reha S. Erzurumlu, and Yu Chen

Sci Rep. 2016; 6: 25269. Published online 2016 Apr 29. doi: 10.1038/srep25269
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM02
An analysis of nonlinear dynamics underlying neural activity related to auditory induction in the rat auditory cortex.

M. Noto, J. Nishikawa and T. Tateno

Neuroscience. 2016 Mar 24;318:58-83. doi: 10.1016/j.neuroscience.2015.12.060. Epub 2016 Jan 7.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
Response reliability observed with voltage-sensitive dye imaging of cortical layer 2/3: The Probability of Activation Hypothesis.

Clare A. Gollnick, Daniel C Millard, Alexander D Ortiz, Ravi V Bellamkonda and Garrett B. Stanley

J Neurophysiol. 2016 Feb 10:jn.00547.2015. doi: 10.1152/jn.00547.2015. [Epub ahead of print]
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
Propagation of spontaneous slow-wave activity across columns and layers of the adult rat barrel cortex in vivo.

Vicente Reyes-Puerta, Jenq-Wei Yang, Magdalena E. Siwek, Werner Kilb, Jyh-Jang Sun and Heiko J. Luhmann

Brain Struct Funct. 2016 Jan 11. [Epub ahead of print]
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Corticospinal axons make direct synaptic connections with spinal motoneurons innervating forearm muscles early during postnatal development in the rat.

Hitoshi Maeda, Satoshi Fukuda, Hiroshi Kameda, Naoyuki Murabe, Noriko Isoo, Hiroaki Mizukami, Keiya Ozawa and Masaki Sakurai

J Physiol. 2016 Jan 1;594(1):189-205. doi: 10.1113/JP270885. Epub 2015 Dec 13.
Slice
(spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM02
Electrographic Waveform Structure Predicts Laminar Focus Location in a Model of Temporal Lobe Seizures In Vitro.

Christopher Adams, Natalie E. Adams, Roger D. Traub, and Miles A. Whittington

PLoS One. 2015; 10(3): e0121676.
Slice
(hippocampus)
VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Midline section of the medulla abolishes inspiratory activity and desynchronizes pre-inspiratory neuron rhythm on both sides of the medulla in newborn rats.

Hiroshi Onimaru, Kayo Tsuzawa, Yoshimi Nakazono and Wiktor A. Janczewski

J Neurophysiol. 2015 Apr; 113(7): 2871?2878.
Brain stem-spinal cordVSD
(Di-2-ANEPEQ)
MiCAM01
Prolonged Intracellular Na+ Dynamics Govern Electrical Activity in Accessory Olfactory Bulb Mitral Cells.

Asaph Zylbertal, Anat Kahan, Yoram Ben-Shaul, Yosef Yarom, and Shlomo Wagner

PLoS Biol. 2015 Dec; 13(12): e1002319. Published online 2015 Dec 16. doi: 10.1371/journal.pbio.1002319
Slice
(olfactory bulb)
CaSD
(Oregon Green BAPTA-1)
MiCAM ULTIMA
In Vivo Voltage-Sensitive Dye Imaging of Subcortical Brain Function.

Qinggong Tang, Vassiliy Tsytsarev, Chia-Pin Liang, Fatih Akkentli, Reha S. Erzurumlu and Yu Chen

Sci Rep. 2015 Nov 27;5:17325. doi: 10.1038/srep17325.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
Long-Term Spatiotemporal Reconfiguration of Neuronal Activity Revealed by Voltage-Sensitive Dye Imaging in the Cerebellar Granular Layer.

Daniela Gandolfi, Jonathan Mapelli and Egidio D' Angelo

Neural Plasticity Volume 2015 (2015), Article ID 284986, 13 pages
Slice
(cerebellum)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
In Vivo Voltage-Sensitive Dye Study of Lateral Spreading of Cortical Activity in Mouse Primary Visual Cortex Induced by a Current Impulse.

Tamás Dávid Fehérvári, Yuka Okazaki, Hajime Sawai, Tetsuya Yagi

PLoS One. 2015 Jul 31;10(7):e0133853. doi: 10.1371/journal.pone.0133853. eCollection 2015.
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Effect of carbamazepine and gabapentin on excitability in the trigeminal subnucleus caudalis of neonatal rats using a voltage-sensitive dye imaging technique.

Akiko Matsumoto, Hirofumi Arisaka, Yuki Hosokawa, Shigeki Sakuraba, Takeo Sugita, Nobuo Umezawa, Yuki Kaku, Kazu-ichi Yoshida and Shun-ichi Kuwana

Biol Res. 2015 Jul 21;48:36. doi: 10.1186/s40659-015-0027-6.
Slice
(brainstem)
VSD
(Di-4-ANEPPS)
MiCAM02
A transparent epidural electrode array for use in conjunction with optical imaging.

Nobuo Kunori and Ichiro Takashima

J Neurosci Methods. 2015 Aug 15;251:130-7. doi: 10.1016/j.jneumeth.2015.05.018. Epub 2015 Jun 4.
In Vivo
(cortex)
VSD
(RH-795)
MiCAM01
Early exposure to urethane anesthesia: Effects on neuronal activity in the piriform cortex of the developing brain.

Riichi Kajiwara and Ichiro Takashima

Neurosci Lett. 2015 Jul 23;600:121-6. doi: 10.1016/j.neulet.2015.06.012. Epub 2015 Jun 9.
Isolated whole brainVSD
(Di-4-ANEPPS)
MiCAM02
Functional optical probing of the hippocampal trisynaptic circuit in vitro: network dynamics, filter properties, and polysynaptic induction of CA1 LTP.

Jens Stepan, Julien Dine and Matthias Eder

Front Neurosci. 2015 May 6;9:160. doi: 10.3389/fnins.2015.00160. eCollection 2015.
Slice
(hippocampus)
VSD
(?)
MiCAM02
An inhibitory pathway controlling the gating mechanism of the mouse lateral amygdala revealed by voltage-sensitive dye imaging.

Tomomi Fujieda, Noriko Koganezawa, Yoshinori Ide, Tomoaki Shirao and Yuko Sekino

Neurosci Lett. 2015 Mar 17;590:126-31. doi: 10.1016/j.neulet.2015.01.079. Epub 2015 Jan 31.
Slice
(amygdala)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
All-optical mapping of barrel cortex circuits based on simultaneous voltage-sensitive dye imaging and channelrhodopsin-mediated photostimulation.

Shun Qiang Lo, Dawn X. P. Koh, Judy C. G. Sng and George J. Augustine

Neurophoton. 2(2), 021013 (Mar 31, 2015). doi:10.1117/1.NPh.2.2.021013.
Slice
(barrel cortex)
VSD
(Di-2-ANBDQPQ)
MiCAM02
Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice.

Yu Zhang, Audrey Bonnan, Guillaume Bony, Isabelle Ferezou, Susanna Pietropaolo, Melanie Ginger, Nathalie Sans, Jean Rossier, Ben Oostra, Gwen LeMasson and Andreas Frick

Nat Neurosci. 2014 Dec;17(12):1701-9. doi: 10.1038/nn.3864. Epub 2014 Nov 10.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome.

Feng Gu, Anupam Hazra, Ahmad Aulakh and Jokūbas Žiburkus

Epilepsia. 2014 Feb;55(2):245-55. doi: 10.1111/epi.12487. Epub 2014 Jan 13.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Optical imaging of neuronal activity and visualization of fine neural structures in non-desheathed nervous systems.

Christopher John Goldsmith, Carola Städele and Wolfgang Stein

PLoS One. 2014 Jul 25;9(7):e103459. doi: 10.1371/journal.pone.0103459. eCollection 2014.
Stomatogastric ganglionVSD
(RH-795)
MiCAM02
Thalamic NMDA Receptor Function Is Necessary for Patterning of the Thalamocortical Somatosensory Map and for Sensorimotor Behaviors.

Hiroyuki Arakawa, Ayumi Suzuki, Shuxin Zhao, Vassiliy Tsytsarev, Fu-Sun Lo, Yu Hayashi, Shigeyoshi Itohara, Takuji Iwasato and Reha S. Erzurumlu

J Neurosci. 2014 Sep 3;34(36):12001-14. doi: 10.1523/JNEUROSCI.1663-14.2014.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM02
Wide-field in vivo neocortical calcium dye imaging using a convection-enhanced loading technique combined with simultaneous multiwavelength imaging of voltage-sensitive dyes and hemodynamic signals.

Hongtao Ma, Samuel Harris, Redi Rahmani, Clay O. Lacefield, Mingrui Zhao, Andy G. S. Daniel, Zhiping Zhou, Randy M. Bruno, Jason Berwick and Theodore H. Schwartz

Neurophoton. 1(1), 015003 (Jul 24, 2014). doi:10.1117/1.NPh.1.1.015003.
In Vivo
(cortex)
VSD
(RH-1691)

CaSD
(OGB-1)
MiCAM ULTIMA
Voltage-sensitive dye imaging of primary motor cortex activity produced by ventral tegmental area stimulation.

Nobuo Kunori, Riichi Kajiwara and Ichiro Takashima

J Neurosci. 2014 Jun 25;34(26):8894-903. doi: 10.1523/JNEUROSCI.5286-13.2014.
In Vivo
(primary motor cortex)
VSD
(RH-795)
MiCAM01
Greenwood frequency-position relationship in the primary auditory cortex in guinea pigs.

Masataka Nishimura and Wen-Jie Song

Neuroimage. 2014 Apr 1;89:181-91. doi: 10.1016/j.neuroimage.2013.12.014. Epub 2013 Dec 14.
In Vivo
(auditory cortex)
VSD
(RH-795)
MiCAM ULTIMA
Anatomical and functional pathways of rhythmogenic inspiratory premotor information flow originating in the pre-Bötzinger complex in the rat medulla.

Naohiro Koshiya, Yoshitaka Oku, Shigefumi Yokota, Yoshitaka Oyamada, Yukihiko Yasui and Yasumasa Okada

Neuroscience. 2014 May 30;268:194-211. doi: 10.1016/j.neuroscience.2014.03.002. Epub 2014 Mar 18.
Slice
(medulla)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Figure-Ground Processing during Fixational Saccades in V1: Indication for Higher-Order Stability.

Ariel Gilad, Yair Pesoa, Inbal Ayzenshtat and Hamutal Slovin

J Neurosci. 2014 Feb 26;34(9):3247-52. doi: 10.1523/JNEUROSCI.4375-13.2014.
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM ULTIMA
High-resolution spatio-temporal bioactivity of a novel peptide revealed by optical imaging in rat orbitofrontal cortex in vitro: Possible implications for neurodegenerative diseases.

Antoine-Scott Badin, John Eraifej and Susan Greenfield

Neuropharmacology. 2013 Oct;73:10-8. doi: 10.1016/j.neuropharm.2013.05.019. Epub 2013 May 24.
Slice
(cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Probing the function of neuronal populations: Combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging.

Sachiko Tsuda, Michelle Z.L. Kee, Catarina Cunha, Jinsook Kim, Ping Yan, Leslie M. Loew and George J. Augustine

Neurosci Res. 2013 Jan;75(1):76-81. doi: 10.1016/j.neures.2012.11.006. Epub 2012 Dec 17.
Slice
(cerebellar cortex)
VSD
(Di-2-ANBDQPQ)
MiCAM02
Functional significance of cortical NMDA receptors in somatosensory information processing.

Fu-Sun Lo, Fatih Akkentli, Vassiliy Tsytsarev and Reha S Erzurumlu

J Neurophysiol. 2013 Dec;110(11):2627-36. doi: 10.1152/jn.00052.2013. Epub 2013 Sep 18.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM02
Comparison of two voltage-sensitive dyes and their suitability for long-term imaging of neuronal activity.

Stephanie Preuss and Wolfgang Stein

PLoS One. 2013 Oct 4;8(10):e75678. doi: 10.1371/journal.pone.0075678.
Stomatogastric ganglionVSD
(Di-4-ANEPPS or Rh-795)
MiCAM02
Gating of long-term potentiation by nicotinic acetylcholine receptors at the cerebellum input stage.

Francesca Prestori, Claudia Bonardi, Lisa Mapelli, Paola Lombardo, Rianne Goselink, Maria Egle De Stefano, Daniela Gandolfi, Jonathan Mapelli, Daniel Bertrand, Martijn Schonewille, Chris De Zeeuw and Egidio D’Angelo

PLoS One. 2013 May 31;8(5):e64828. doi: 10.1371/journal.pone.0064828. Print 2013.
Slice
(cerebellum)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
In vivo minimally invasive interstitial multi-functional microendoscopy.

Asaf Shahmoon, Shiran Aharon, Oded Kruchik, Martin Hohmann, Hamutal Slovin, Alexandre Douplik and Zeev Zalevsky

Sci Rep. 2013; 3: 1805.Published online 2013 May 28. doi: 10.1038/srep01805
In Vivo
(barrel cortex)
MiCAM ULTIMA
Inhibitory neuron and hippocampal circuit dysfunction in an aged mouse model of Alzheimer's disease.

Anupam Hazra, Feng Gu, Ahmad Aulakh, Casey Berridge, Jason L. Eriksen and Jokūbas Žiburkus

PLoS One. 2013 May 17;8(5):e64318. doi: 10.1371/journal.pone.0064318. Print 2013.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Temporally-structured acquisition of multidimensional optical imaging data facilitates visualization of elusive cortical representations in the behaving monkey.

David B. Omer, Rina Hildesheim and Amiram Grinvald

Neuroimage. 2013 Nov 15;82:237-51. doi: 10.1016/j.neuroimage.2013.05.045. Epub 2013 May 18.
In Vivo
(cortex)
VSD
(RH-1916)
MiCAM ULTIMA
In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe.

Vassiliy Tsytsarev, Hiroyuki Arakawa, Sergei Borisov, Elena Pumbo, Reha S. Erzurumlu and Dmitri B. Papkovsky

J Neurosci Methods. 2013 Jun 15;216(2):146-51. doi: 10.1016/j.jneumeth.2013.04.005. Epub 2013 Apr 25.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM02
Theta-frequency resonance at the cerebellum input stage improves spike timing on the millisecond time-scale.

Daniela Gandolfi, Paola Lombardo, Jonathan Mapelli, Sergio Solinas and Egidio D'Angelo

Front Neural Circuits. 2013 Apr 10;7:64. doi: 10.3389/fncir.2013.00064. Print 2013.
Slice
(cerebellum)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Spatiotemporal coordination of slow-wave ongoing activity across auditory cortical areas.

Brandon J. Farley and Arnaud J. Noreña

J Neurosci. 2013 Feb 20;33(8):3299-310. doi: 10.1523/JNEUROSCI.5079-12.2013.
In Vivo
(auditory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Identification of a role for the ventral hippocampus in neuropeptide s-elicited anxiolysis.

Julien Dine, Irina A. Ionescu, Jens Stepan, Yi-Chun Yen, Florian Holsboer, Rainer Landgraf and Matthias Eder and Ulrike Schmidt

PLoS One. 2013;8(3):e60219. doi: 10.1371/journal.pone.0060219. Epub 2013 Mar 28.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Cell-type specific inactivation of hippocampal CA1 disrupts location-dependent object recognition in the mouse.

Jakob Haettig, Yanjun Sun, Marcelo A. Wood and Xiangmin Xu

Learn Mem. 2013 Feb 15;20(3):139-46. doi: 10.1101/lm.027847.112.
Slice
(hippocampus)
VSD
(NK3630/RH-482)
MiCAM02
Somatotopic astrocytic activity in the somatosensory cortex.

Ghosh Arko, Wyss Matthias T and Weber Bruno

Glia. 2013 Apr;61(4):601-10. doi: 10.1002/glia.22458. Epub 2013 Jan 22.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Anatomical and electrophysiological mechanisms for asymmetrical excitatory propagation in the rat insular cortex: In vivo optical imaging and whole-cell patch-clamp studies.

Kazunori Adachi, Satoshi Fujita, Atsushi Yoshida, Hiroshi Sakagami, Noriaki Koshikawa and Masayuki Kobayashi

J Comp Neurol. 2013 May 1;521(7):1598-613. doi: 10.1002/cne.23246.
In Vivo
(insular cortex)
VSD
(RH-1691)
MiCAM02
Optical stimulation and imaging of functional brain circuitry in a segmented laminar flow chamber.

Siavash Ahrar, Transon V. Nguyen, Yulin Shi, Taruna Ikrar, Xiangmin Xu and Elliot E. Hui

Lab Chip. 2013 Feb 21;13(4):536-41. doi: 10.1039/c2lc40689f.
Slice
(hippocampus)
VSD
(NK3630/RH-482)
MiCAM02
An evaluation of in vivo voltage-sensitive dyes: pharmacological side effects and signal-to-noise ratios after effective removal of brain-pulsation artifacts.

Thomas H. Grandy, Susan A. Greenfield and Ian M. Devonshire

J Neurophysiol. 2012 Dec;108(11):2931-45. doi: 10.1152/jn.00512.2011. Epub 2012 Sep 12.
In Vivo
(cortex)
VSD
(RH-1691 and Di-4-ANEPPS)
MiCAM ULTIMA
Long-range parallel processing and local recurrent activity in the visual cortex of the mouse.

Pierre-Olivier Polack and Diego Contreras

J Neurosci. 2012 Aug 8;32(32):11120-31. doi: 10.1523/JNEUROSCI.6304-11.2012.
In Vivo
(visual cortex)
VSD
(RH-1838)
MiCAM02
NMDA receptor regulation prevents regression of visual cortical function in the absence of Mecp2.

Severine Durand, Annarita Patrizi, Kathleen B. Quast, Lea Hachigian, Roman Pavlyuk, Alka Saxena, Piero Carninci, Takao K. Hensch and Michela Fagiolini

Neuron. 2012 Dec 20;76(6):1078-90. doi: 10.1016/j.neuron.2012.12.004.
Slice
(visual cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Laminar circuit organization and response modulation in mouse visual cortex.

Nicholas D. Olivas, Victor Quintanar-Zilinskas, Zoran Nenadic and Xiangmin Xu

Front Neural Circuits. 2012;6:70. doi: 10.3389/fncir.2012.00070. Epub 2012 Oct 5.
Slice
(visual cortex)
VSD
(NK3630/RH-482)
MiCAM02
Priming with real motion biases visual cortical response to bistable apparent motion.

Qing-fang Zhanga, Yunqing Wena, Deng Zhanga, Liang Shea, Jian-young Wub, Yang Dan and Mu-ming Poo

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20691-6. doi: 10.1073/pnas.1218654109. Epub 2012 Nov 27.
In Vivo
(visual cortex)
VSD
(RH-1691)
MiCAM ULTIMA
All layers of medial entorhinal cortex receive presubicular and parasubicular inputs.

Cathrin B. Canto, Noriko Koganezawa, Prateep Beed, Edvard I. Moser, and Menno P. Witter

J Neurosci. 2012 Dec 5;32(49):17620-31. doi: 10.1523/JNEUROSCI.3526-12.2012.
Slice
(hippocampus)
VSD
(RH-795)
MiCAM ULTIMA
Collinear Stimuli Induce Local and Cross-Areal Coherence in the Visual Cortex of Behaving Monkeys.

Ariel Gilad, Elhanan Meirovithz, Amir Leshem, Amos Arieli and Hamutal Slovin

PLoS One. 2012;7(11):e49391. doi: 10.1371/journal.pone.0049391. Epub 2012 Nov 19.
In Vivo
(visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses.

James P. Clement, Massimiliano Aceti, Thomas K. Creson, Emin D. Ozkan, Yulin Shi, Nicholas J. Reish, Antoine G. Almonte, Brooke H. Miller, Brian J. Wiltgen, Courtney A. Miller, Xiangmin Xu and Gavin Rumbaugh

Cell. 2012 Nov 9;151(4):709-23. doi: 10.1016/j.cell.2012.08.045.
Slice
(hippocampus)
VSD
(?)
MiCAM02
Population Response to Natural Images in the Primary Visual Cortex Encodes Local Stimulus Attributes and Perceptual Processing.

Inbal Ayzenshtat, Ariel Gilad, Guy Zurawel and Hamutal Slovin

J Neurosci. 2012 Oct 3;32(40):13971-86. doi: 10.1523/JNEUROSCI.1596-12.2012.
In Vivo
(visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Capsaicin induces theta-band synchronization between gustatory and autonomic insular cortices.

Mitsuru Saito, Hiroki Toyoda, Shinpei Kawakami, Hajime Sato, Yong Chul Bae and Youngnam Kang

J Neurosci. 2012 Sep 26;32(39):13470-87.
Slice
(insular cortex)
VSD
(RH-414)
MiCAM02
Entorhinal theta-frequency input to the dentate gyrus trisynaptically evokes hippocampal CA1 LTP.

Jens Stepan, Julien Dine, Thomas Fenzl, Stephanie A. Polta, Gregor von Wolff, Carsten T. Wotjak and Matthias Eder

Front Neural Circuits. 2012; 6: 64.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Rapid Whisker Movements in Sleeping Newborn Rats.

Alexandre Tiriac, Brandt D. Uitermarkt, Alexander S. Fanning, Greta Sokoloff and Mark S. Blumberg

Curr Biol. 2012 Nov 6;22(21):2075-80. doi: 10.1016/j.cub.2012.09.009. Epub 2012 Oct 18.
In Vivo
(barrel cortex)
VSD
(RH-1838)
MiCAM ULTIMA
Stroke induces long-lasting deficits in the temporal fidelity of sensory processing in the somatosensory cortex.

Danielle A Sweetnam and Craig E Brown

J Cereb Blood Flow Metab. 2012 Sep 19. doi: 10.1038/jcbfm.2012.135. [Epub ahead of print]
In Vivo
(somatosensory cortex)
VSD
(RH-1692)
MiCAM02
Imaging the Spatio-Temporal Dynamics of Supragranular Activity in the Rat Somatosensory Cortex in Response to Stimulation of the Paws.

M. L. Morales-Botello, J. Aguilar, G. Foffani

PLoS ONE 7(7): e40174. doi:10.1371/journal.pone.0040174
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Long-Term Potentiation in the Neonatal Rat Barrel Cortex In Vivo.

Shuming An, Jenq-Wei Yang, Haiyan Sun, Werner Kilb and Heiko J. Luhmann

J Neurosci. 2012 Jul 11;32(28):9511-6.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Cell-type specific regulation of cortical excitability through the allatostatin receptor system.

Taruna Ikrar, Yulin Shi, Tomoko Velasquez, Martyn Goulding and Xiangmin Xu

Front Neural Circuits. 2012;6:2. Epub 2012 Jan 20.
Slice
(cortex)
VSD
(NK3630/RH-482)
MiCAM02
Diabetes impairs cortical plasticity and functional recovery following ischemic stroke.

Danielle Sweetnam, Andrew Holmes, Kelly A. Tennant, Akram Zamani, Mark Walle, Paul Jones, Charles Wong and Craig E. Brown

J Neurosci. 2012 Apr 11;32(15):5132-43.
In Vivo
(somatosensory cortex)
VSD
(RH-1692)
MiCAM02
α4* Nicotinic acetylcholine receptors modulate experience-based cortical depression in the adult mouse somatosensory cortex.

Craig E. Brown, Danielle Sweetnam, Maddie Beange, Patrick C. Nahirney and Raad Nashmi

J Neurosci. 2012 Jan 25;32(4):1207-19.
In Vivo
(somatosensory cortex)
VSD
(RH-1692)
MiCAM02
Spatiotemporal profiles of transcallosal connections in rat insular cortex revealed by in vivo optical imaging.

S. Fujita, T. Kitayama, N. Mizoguchi, Y. Oi, N. Koshikawa, M. Kobayashi

Neuroscience. 2012 Mar 29;206:201-11. Epub 2012 Jan 18.
In Vivo
(insular cortex)
VSD
(RH-1691)
MiCAM02
Thalamic Network Oscillations Synchronize Ontogenetic Columns in the Newborn Rat Barrel Cortex.

Jenq-Wei Yang, Shuming An, Jyh-Jang Sun, Vicente Reyes-Puerta, Jennifer Kindler, Thomas Berger, Werner Kilb and Heiko J. Luhmann

Cereb Cortex. 2012 May 16. [Epub ahead of print]
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex.

Nicolas Narboux-Nême, Alexis Evrard, Isabelle Ferezou, Reha S. Erzurumlu, Pascal S. Kaeser, Jeanne Lainé, Jean Rossier, Nicole Ropert, Thomas C. Südhof and Patricia Gaspar

J Neurosci. 2012 May 2;32(18):6183-96.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Detection of Tactile Inputs in the Rat Vibrissa Pathway.

Douglas R. Ollerenshaw, Bilal A. Bari, Daniel C. Millard, Lauren E. Orr, Qi Wang and Garrett B. Stanley

J Neurophysiol. 2012 Apr 18. [Epub ahead of print]
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM02
Beta adrenergic modulation of spontaneous spatiotemporal activity patterns and synchrony in hyper-excitable hippocampal circuits.

Anupam Hazra, Robert Rosenbaum, Bernhard Bodmann, Siyuan Cao, Kresimir Josic and Jokubas Ziburkus

J Neurophysiol. 2012 Apr 11. [Epub ahead of print]
Slice
(hippocampus)
VSD
(Di-4-ANEPPS and Di-8-ANEPPS)
MiCAM ULTIMA
Dynamic Neurovascular Coupling and Uncoupling during Ictal Onset, Propagation, and Termination Revealed by Simultaneous In Vivo Optical Imaging of Neural Activity and Local Blood Volume.

Hongtao Ma, Mingrui Zhao and Theodore H. Schwartz

Cereb Cortex. 2012 Apr 11. [Epub ahead of print]
In Vivo
(cortex)
VSD
(RH-1691 or RH-1692)
MiCAM ULTIMA
Endogenously released ACh and exogenous nicotine differentially facilitate long-term potentiation induction in the hippocampal CA1 region of mice.

Sakura Nakauchi and Katumi Sumikawa

Eur J Neurosci. 2012 May;35(9):1381-95. doi: 10.1111/j.1460-9568.2012.08056.x. Epub 2012 Mar 30.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Voltage-sensitive dye imaging reveals improved topographic activation of cortex in response to manipulation of thalamic microstimulation parameters.

Qi Wang, Daniel C Millard, He J V Zheng and Garrett B Stanley

J Neural Eng. 2012 Feb 13;9(2):026008. [Epub ahead of print]
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM02
Cell-type specific regulation of cortical excitability through the allatostatin receptor system.

Taruna Ikrar, Yulin Shi, Tomoko Velasquez, Martyn Goulding and Xiangmin Xu

Front Neural Circuits. 2012;6:2. Epub 2012 Jan 20.
Slice
(cortex)
VSD
(NK3630/RH-482)
MiCAM02
Visual experience modulates spatio-temporal dynamics of circuit activation.

Lang Wang, Alfredo Fontanini and Arianna Maffei

Front Cell Neurosci. 2011;5:12. Epub 2011 Jun 28.
Slice
(visual cortex)
VSD
(Di-4-ANEPPS)
MiCAM02
Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus.

Kyung-Seok Han, Guido Mannaioni, Cecily E Hamill, Jaekwang Lee, Candice E Junge, C Justin Lee and Stephen F Traynelis

Mol Brain. 2011 Aug 10;4:32.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Identification and characterization of an insular auditory field in mice.

Hiroyuki Sawatari, Yoshihide Tanaka, Makoto Takemoto, Masataka Nishimura, Kayoko Hasegawa, Kazuya Saitoh and Wen-Jie Song

Eur J Neurosci. 2011 Dec;34(12):1944-52. doi: 10.1111/j.1460-9568.2011.07926.x. Epub 2011 Nov 25.
In Vivo
(cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Entorhinal cortex layer III input to the hippocampus is crucial for temporal association memory.
Junghyup Suh, Alexander J. Rivest, Toshiaki Nakashiba, Takashi Tominaga and Susumu Tonegawa

Science. 2011 Dec 9;334(6061):1415-20. Epub 2011 Nov 3.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Simultaneous measurement of membrane potential changes in multiple pattern generating neurons using voltage sensitive dye imaging.

Carola Städele, Peter Andras and Wolfgang Stein

J Neurosci Methods. 2012 Jan 15;203(1):78-88. Epub 2011 Sep 22.
Crab stomatogastric ganglionVSD
(Di-4-ANEPPS)
MiCAM02
Spatiotemporal Effects of Microsaccades on Population Activity in the Visual Cortex of Monkeys during Fixation.

Elhanan Meirovithz, Inbal Ayzenshtat, Uri Werner-Reiss, Itay Shamir and Hamutal Slovin

Cereb Cortex. 2011 Jun 7. [Epub ahead of print]
In Vivo
(monkey visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Spatiotemporal dynamics of long-term potentiation in rat insular cortex revealed by optical imaging.

Naoko Mizoguchi, Satoshi Fujita, Noriaki Koshikawa and Masayuki Kobayashi

Neurobiol Learn Mem. 2011 Oct;96(3):468-78. Epub 2011 Aug 9.
In Vivo
(insular cortex)
VSD
(RH-1691)
MiCAM02
Spatiotemporal and anatomical analyses of P2X receptor-mediated neuronal and glial processing of sensory signals in the rat dorsal horn.

Ryoma Aoyama, Yasumasa Okada, Shigefumi Yokota, Yutaka Yasui, Kentaro Fukuda, Yoshio Shinozaki, Hideaki Yoshida, Masaya Nakamura, Kazuhiro Chiba, Yukihiko Yasui, Fusao Kato and Yoshiaki Toyama

Pain. 2011 Sep;152(9):2085-97. Epub 2011 Jun 12.
Slice
(spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM01
Associative Properties of the Perirhinal Network.

Gunes Unal, John Apergis-Schoute and Denis Paré

Cereb Cortex. 2011 Aug 12. [Epub ahead of print]
Isolated whole brainVSD
(Di-2-ANEPEQ)
MiCAM02
In vivo evidence for lactate as a neuronal energy source.

Matthias T. Wyss, Renaud Jolivet, Alfred Buck, Pierre J. Magistretti and Bruno Weber

J Neurosci. 2011 May 18;31(20):7477-85.
In Vivo
(somatosensory cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Oligodendrocytes as Regulators of Neuronal Networks during Early Postnatal Development.

Sandrine Doretto, Monica Malerba, Maria Ramos, Taruna Ikrar, Chisato Kinoshita, Claudia De Mei, Emanuele Tirotta, Xiangmin Xu and Emiliana Borrelli

PLoS One. 2011 May 12;6(5):e19849.
Slice
(cerebellar cortex)
VSD
(NK3630/RH-482)
MiCAM02
Stimulus-dependent changes in optical responses of the dorsal cochlear nucleus using voltage-sensitive dye.

Frank G Licari, Mahdi Shkoukani and James A Kaltenbach

J Neurophysiol. 2011 May 4. [Epub ahead of print]
In Vivo
(hamster dorsal cochlear nucleus)
VSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
The membrane chamber: a new type of in vitro recording chamber.

Hill MR and Greenfield SA

J Neurosci Methods. 2011 Jan 30;195(1):15-23. Epub 2010 Nov 12.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Optical Imaging of Somatosensory Evoked Potentials in the Rat Cerebral Cortex after Spinal Cord Injury.

Kyung Hee Lee, Un Jeng Kim, Yong Gou Park, Ran Won, Hyejung Lee and Bae Hwan Lee

J Neurotrauma. 2011 Apr 12. [Epub ahead of print]
In Vivo
(Somatosensory cortex)
VSD
(Di-2-ANEPEQ)
MiCAM02
Linking topography to tonotopy in the mouse auditory thalamocortical circuit.

Troy A. Hackett, Tania Rinaldi Barkat, Barbara MJ. O’Brien, Takao K. Hensch and Daniel B. Polley

J Neurosci. 2011 Feb 23;31(8):2983-95.
Slice
(auditory thalamocortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optical imaging of propofol-induced central respiratory depression in medulla-spinal cord preparations from newborn rats.

Masanori Kashiwagi, Yoshimune Osaka, Hiroshi Onimaru and Junzo Takeda

Clin Exp Pharmacol Physiol. 2011 Jan 19. doi: 10.1111/j.1440-1681.2011.05480.x. [Epub ahead of print]
Medulla?spinal cord preparationVSD
(Di-2-ANEPEQ)
MiCAM01
Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes (Video Article).

Wolfgang Stein, Carola Städele and Peter Andras

doi: 10.3791/2567. J Vis Exp. 49 (2011)
Crab stomatogastric ganglionVSD
(Di-8-ANEPPQ)
MiCAM02
Detection and visualization method of dynamic state transition for biological spatio-temporal imaging data.

Fumikazu Miwakeichi, Yoshitaka Oku, Yasumasa Okada, Shigeharu Kawai, Yoshiyasu Tamura and Makio Ishiguro

IEEE Trans Med Imaging. 2011 Mar;30(3):859-66. Epub 2011 Jan 10.
Isolated brainstemVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Single-sweep voltage-sensitive dye imaging of interacting identified neurons.

Wolfgang Stein, Carola Städele and Peter Andras

J Neurosci Methods. 2011 Jan 15;194(2):224-34. Epub 2010 Oct 20.
Crab stomatogastric ganglionVSD
(Di-8-ANEPPQ)
MiCAM02
Environmental enrichment differentially modifies specific components of sensory-evoked activity in rat barrel cortex as revealed by simultaneous electrophysiological recordings and optical imaging in vivo.

Ian M. Devonshire, Eleanor J. Dommett, Thomas H. Grandy, Amy C Halliday and Susan A. Greenfield

Neuroscience. 2010 Oct 13;170(2):662-9. Epub 2010 Jul 21.
In Vivo
(barrel cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Effects of urethane anaesthesia on sensory processing in the rat barrel cortex revealed by combined optical imaging and electrophysiology.

Ian M. Devonshire, Thomas H. Grandy, Eleanor J. Dommett and Susan A. Greenfield

Eur J Neurosci. 2010 Sep;32(5):786-97. doi: 10.1111/j.1460-9568.2010.07322.x. Epub 2010 Jul 14.
In Vivo
(barrel cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
TRP channels are involved in mediating hypercapnic Ca(2+) responses in rat glia-rich medullary cultures independent of extracellular pH.

Yutaka Hirata and Yoshitaka Oku

Cell Calcium. 2010 Aug-Sep;48(2-3):124-32. Epub 2010 Aug 21.
Cell culture
(medullary cells)
CaSD
(Fluo-4)
MiCAM ULTIMA
Astrocytes control breathing through pH-dependent release of ATP.

Alexander V. Gourine, Vitaliy Kasymov, Nephtali Marina, Feige Tang, Melina F. Figueiredo, Samantha Lane, Anja G. Teschemacher, K. Michael Spyer, Karl Deisseroth and Sergey Kasparov

Science. 2010 Jul 30;329(5991):571-5. Epub 2010 Jul 15.
In Vivo
(brainstem)
GECI
(Case12)
MiCAM02
Precise spatiotemporal patterns among visual cortical areas and their relation to visual stimulus processing.

Inbal Ayzenshtat, Elhanan Meirovithz, Hadar Edelman, Uri Werner-Reiss, Elie Bienenstock, Moshe Abeles and Hamutal Slovin

J Neurosci. 2010 Aug 18;30(33):11232-45.
In Vivo
(monkey visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

Takae Ohno, Hitoshi Maeda, Naoyuki Murabe, Tsutomu Kamiyama, Noboru Yoshioka, Masayoshi Mishina and Masaki Sakurai

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15252-7. Epub 2010 Aug 9.
Slice
(spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM02
Spatiotemporal patterns of neural activity in response to electroacupuncture stimulation in the rodent primary somatosensory cortex.

Younbyoung Chae, Hi-Joon Park, Dae-Hyun Hahm, Bae-Hwan Lee, Hun-Kuk Park and Hyejung Lee

Neurol Res. 2010 Feb;32 Suppl 1:64-8.
In Vivo
(somatosensory cortex)
VSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation.

Gregor von Wolff, Charilaos Avrabos, Jens Stepan, Wolfgang Wurst, Jan M. Deussing, Florian Holsboer and Matthias Eder

J Psychiatr Res. 2010 Jul 7. [Epub ahead of print]
Slice
(hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
High-Pass Filtering and Dynamic Gain Regulation Enhance Vertical Bursts Transmission along the Mossy Fiber Pathway of Cerebellum.

Jonathan Mapelli, Daniela Gandolfi, and Egidio D'Angelo

Front Cell Neurosci. 2010 May 28;4:14.
Slice
(cerebellar cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Light-induced effects of a fluorescent voltage-sensitive dye on neuronal activity in the crab stomatogastric ganglion.

Wolfgang Stein and Peter Andras

J Neurosci Methods. 2010 May 15;188(2):290-4.
Stomatogastric nervous system
(crab)
VSD
(Di-4-ANEPPS)
MiCAM02
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures.

Feng Zhang, Viviana Gradinaru, Antoine R Adamantidis, Remy Durand, Raag D Airan, Luis de Lecea and Karl Deisseroth

Nat Protoc. 2010 Mar;5(3):439-56. Epub 2010 Feb 18.
In Vivo
(cortex)
VSD
(RH-155)
MiCAM02
Functional interactions within the parahippocampal region revealed by voltage-sensitive dye imaging in the isolated guinea pig brain.

Gerardo Biella, Paolo Spaiardi, Mauro Toselli, Marco de Curtis and Vadym Gnatkovsky

J Neurophysiol. 2010 Feb;103(2):725-32. Epub 2009 Nov 25.
Isolated guinea pig brainVSD
(Di-2-ANEPEQ)
MiCAM02
High precision and fast functional mapping of cortical circuitry through a combination of voltage sensitive dye imaging and laser scanning photostimulation.

Xiangmin Xu, Nicholas D. Olivas, Rafael Levi, Taruna Ikrar and Zoran Nenadic

J Neurophysiol. 2010 Feb 3. [Epub ahead of print]
Slice
(visual cortex)
VSD
(RH-482)
MiCAM02
Properties of synaptic transmission from the reticular formation dorsal to the facial nucleus to trigeminal motoneurons during early postnatal development in rats.

Gemba-Nishimura A, Inoue T, Nakamura S, Nakayama K, Mochizuki A, Shintani S, Yoshimura S.

Neuroscience. 2010 Jan 6. [Epub ahead of print]
Slice
(brainstem)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Combinatorial responses controlled by synaptic inhibition in the cerebellum granular layer.

Jonathan Mapelli, Daniela Gandolfi and Egidio D'Angelo

J Neurophysiol. 2010 Jan;103(1):250-61.
Slice
(cerebellar cortex)
VSD
(Di-4-ANEPPS)
MiCAM01
Rewiring of hindlimb corticospinal neurons after spinal cord injury.

Arko Ghosh, Florent Haiss, Esther Sydekum, Regula Schneider, Miriam Gullo, Matthias T Wyss, Thomas Mueggler, Christof Baltes, Markus Rudin, Bruno Weber and Martin E Schwab

Nat Neurosci. 2010 Jan;13(1):97-104.
In Vivo
(sensorimotor cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Spatiotemporal dynamics of excitation in rat insular cortex: intrinsic corticocortical circuit regulates caudal-rostro excitatory propagation from the insular to frontal cortex.

Satoshi Fujita, Kazunori Adachi, Noriaki Koshikawa and Masayuki Kobayashi

Neuroscience. 2010 Jan 13;165(1):278-92. Epub 2009 Oct 1.
In Vivo
(rat insular cortex)
VSD
(Di-4-ANEPPS)
MiCAM02
Functional mapping of gustatory neurons in the insular cortex revealed by pERK-immunohistochemistry and in vivo optical imaging.

Masayuki Kobayashi, Satoshi Fujita, Hiroki Takei, Liqui Song, Shaoyun Chen, Ikuko Suzuki, Atsushi Yoshida, Koichi Iwata and Noriaki Koshikawa

Synapse. 2010 Apr;64(4):323-34.
In Vivo
(rat insular cortex)
VSD
(RH-1691)
MiCAM02
Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish Cellular organization and neurotransmitters.

Takanori Ikenaga, Tatsuya Ogura and Thomas E. Finger

J Comp Neurol. 2009 Sep 20;516(3):213-25.
Slice
(vagal lobe)
CaSD
(Calcium Green-1 Dextran)
MiCAM02
Upregulation of casein kinase 1epsilon in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain.

Eri Sakurai, Takashi Kurihara, Kasumi Kouchi, Hironao Saegusa, Shuqin Zong and Tsutomu Tanabe

Mol Pain. 2009 Dec 18;5:74.
Slice
(spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM02
State-dependence of climbing fiber-driven calcium transients in Purkinje cells.

Dan Rokni and Yosef Yarom

Neuroscience. 2009 Sep 1;162(3):694-701.
Single Cell
(purkinje cell)
CaSD
(Oregon Green 488 BAPTA-1)
MiCAM ULTIMA
Pilocarpine-induced status epilepticus causes acute interneuron loss and hyper-excitatory propagation in rat insular cortex.

Shaoyun Chen, Satoshi Fujita, Noriaki Koshikawa and Masayuki Kobayashi

Neuroscience. 2009 Dec 16. [Epub ahead of print]
In Vivo
(rat insular cortex)
VSD
(RH-1691)
MiCAM02
Characterization of a nicotine-sensitive neuronal population in rat entorhinal cortex.

Tu B, Gu Z, Shen JX, Lamb PW and Yakel JL

J Neurosci. 2009 Aug 19;29(33):10436-48.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Functional and anatomical reorganization of the sensory-motor cortex after incomplete spinal cord injury in adult rats.

Arko Ghosh, Esther Sydekum, Florent Haiss, Stefano Peduzzi, Björn Zörner, Regula Schneider, Christof Baltes, Markus Rudin, Bruno Weber and Martin E. Schwab

J Neurosci. 2009 Sep 30;29(39):12210-9.
In Vivo
(sensory-motor cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Population Response to Contextual Influences in the Primary Visual Cortex.

Elhanan Meirovithz, Inbal Ayzenshtat, Yoram S. Bonneh, Royi Itzhack, Uri Werner-Reiss and Hamutal Slovin

Cereb Cortex. 2009 Sep 16. [Epub ahead of print]
In Vivo
(monkey visual cortex)
VSD
(RH-1691 or RH-1838)
MiCAM ULTIMA
Opioids prolong and anoxia shortens delay between onset of preinspiratory (pFRG) and inspiratory (preBötC) network bursting in newborn rat brainstems.

Ballanyi K, Ruangkittisakul A and Onimaru H.

Pflugers Arch. 2009 Jul;458(3):571-87. Epub 2009 Mar 4.
Brainstem?spinal cord preparationVSD
(Di-2-ANEPEQ)
MiCAM01
Modification of cortical excitability in neuropathic rats: a voltage-sensitive dye study.

Myeoung Hoon Cha, Dae Shik Kim, Zang-Hee Cho, Jin-Hun Sohn, Myung-Ae Chung, Hye-Jung Lee, Taick Sang Nam and Bae Hwan Lee

Neurosci Lett. 2009 Oct 23;464(2):117-21.
In Vivo
(cerebral cortex)
VSD
(Di-2-ANEPEQ)
MiCAM02
A novel statistical analysis of voltage-imaging data by structural time series modeling and its application to the respiratory neuronal network.

Shigeharu Kawai, Yoshitaka Oku, Yasumasa Okada, Fumikazu Miwakeichi, Yoshiyasu Tamura and Makio Ishiguro

Neurosci Res. 2009 Mar;63(3):165-71.
Brainstem?spinal cord preparationVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Fluorescence imaging of active respiratory networks.

Araya Ruangkittisakul, Yasumasa Okada, Yoshitaka Oku, Naohiro Koshiya and Klaus Ballanyi

Respir Physiol Neurobiol. 2009 Aug 31;168(1-2):26-38.
Brainstem?spinal cord preparation

Brainstem slice
VSD
(Di-4-ANEPPS and Di-2-ANEPEQ)
MiCAM ULTIMA
Membrane potential response profiles of CA1 pyramidal cells probed with voltage-sensitive dye optical imaging in rat hippocampal slices reveal the impact of GABA(A)-mediated feed-forward inhibition in signal propagation.

Yoko Tominaga, Michinori Ichikawa and Takashi Tominaga

Neurosci Res. 2009 Jun;64(2):152-61.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA and MiCAM01
Genetic manipulation, whole-cell recordings and functional imaging of the sensorimotor cortex of behaving mice.

Carl C.H. Petersen

Acta Physiol (Oxf). 2009 Jan;195(1):91-9.
In Vivo
(sensorimotor cortex)
VSD
(RH-1691)
MiCAM ULTIMA
DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death.

Kenji Amano, Morimitsu Fujii, Satoru Arata, Takuro Tojima, Masaharu Ogawa, Noriyuki Morita, Atsushi Shimohata, Teiichi Furuichi, Shigeyoshi Itohara, Hiroyuki Kamiguchi, Julie R. Korenberg, Akiko Arata and Kazuhiro Yamakawa

J Neurosci. 2009 Mar 4;29(9)
Medulla?spinal cordVSD
(Di-2-ANEPEQ)
MiCAM02
Optical imaging of interaural time difference representation in rat auditory cortex.

Vassiliy Tsytsarev, Hidenao Fukuyama, Daniel Pope, Elena Pumbo and Minoru Kimura

Front. Neuroeng. (2009) 2:2.
In Vivo
(rat auditory cortex)
VSD
(RH-795)
MiCAM01
Chemosensitive neuronal network organization in the ventral medulla analyzed by dynamic voltage-imaging.

Yasumasa Okada, Shun-ichi Kuwana, Haruko Masumiya, Naofumi Kimura, Zibin Chen and Yoshitaka Oku

Adv Exp Med Biol. 2008;605:353-7.
Slice
Isolated brainstem?spinal cord
VSD
(Di-4-ANEPPS and Di-2-ANEPEQ)
MiCAM01 or
MiCAM ULTIMA
Synaptic transmission from the supratrigeminal region to jaw-closing and jaw-opening motoneurons in developing rats.

Shiro Nakamura, Tomio Inoue, Kan Nakajima, Masayuki Moritani, Kiyomi Nakayama, Kenichi Tokita, Atsushi Yoshida and Kohtaro Maki

J Neurophysiol. 2008 Oct;100(4):1885-96.
Slice
(brainstem)
VSD
(Di-4-ANEPPS)
MiCAM01 or
MiCAM ULTIMA
Significance of the deep layers of entorhinal cortex for transfer of both perirhinal and amygdala inputs to the hippocampus.

Noriko Koganezawa, Ayaka Taguchi, Takashi Tominaga, Shinya Ohara, Ken-Ichiro Tsutsui, Menno P. Witter and Toshio Iijima

Neurosci Res. 2008 Jun;61(2):172-81.
SliceVSD
(RH-795)
MiCAM ULTIMA
Spatiotemporal organization of frog respiratory neurons visualized on the ventral medullary surface.

Yoshitaka Oku, Naofumi Kimura, Haruko Masumiya and Yasumasa Okada

Respir Physiol Neurobiol. 2008 May 31;161(3):281-90.
Brainstem?spinal cordVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Imaging activity of neuronal populations with new long-wavelength voltage-sensitive dyes.

Michelle Z. L. Kee, Joseph P. Wuskell, Leslie M. Loew, George J. Augustine and Yuko Sekino

Brain Cell Biol. 2008 Dec;36(5-6):157-72.
Slice
(hippocampus)
VSD
(long-wavelengths)
MiCAM02
Reverberation of recent visual experience in spontaneous cortical waves.

Feng Han, Natalia Caporale and Yang Dan

Neuron. 2008 Oct 23;60(2):321-7.
In Vivo
(visual cortex)
VSD
(RH-1838 or RH-1691)
MiCAM ULTIMA
Respiratory neuron group in the high cervical spinal cord discovered by optical imaging.

Yoshitaka Oku, Akihito Okabe, Tetsu Hayakawa and Yasumasa Okada

Neuroreport. 2008 Nov 19;19(17):1739-43.
Brainstem?spinal cordVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Distribution of the olfactory fibre input into the olfactory tubercle of the in vitro isolated guinea pig brain.

Giovanni Carriero, Laura Uva, Vadym Gnatkovsky, and Marco de Curtis

J Neurophysiol. 2008 Oct 15.
Isolated whole-brainVSD
(Di-2-ANEPEQ)
MiCAM02
Imaging of Molecular Dynamics Regulated by Electrical Activities in Neural Circuits and in Synapses.

Ritsuko Fujii, Michinori Ichikawa and Miwako Ozaki

Neurosignals. 2008 Jul 18;16(4):260-277.
Slice
(hippocampus)
VSD
(Di-4-ANEPPS and Di-2-ANEPEQ)
MiCAM ULTIMA
Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning.

Makoto Nishiyama, Melanie J von Schimmelmann, Kazunobu Togashi, William M Findley and Kyonsoo Hong

Nat Neurosci. 2008 Jul;11(7):762-71.
Xenopus spinal neuronsVSD
(Di-2-ANEPEQ)
MiCAM02
(dual camera)
Time-frequency feature extraction from frequency-modulated sounds in a population of auditory cortical neurons.

Shunji Sugimoto, Yuta Suzuki, Hiroyuki Tanaka, Michinori Kubota and Junsei Horikawa

Vol. 29 (2008) , No. 1 Special Issue on the ASA-ASJ joint meeting pp.36-40
In Vivo
(guinea pig auditory cortex)
VSD
(RH-795)
MiCAM ULTIMA
Olfactory information converges in the amygdaloid cortex via the piriform and entorhinal cortices: observations in the guinea pig isolated whole-brain preparation.

Riichi Kajiwara, Takashi Tominaga and Ichiro Takashima

Eur J Neurosci. 2007 Jun;25(12):3648-58.
Isolated whole-brainVSD
(Di-4-ANEPPS)
MiCAM01
Integration of light-controlled neuronal firing and fast circuit imaging.

Raag D Airan, Elbert S Hu, Ragu Vijaykumar, Madhuri Roy, Leslie A Meltzer and Karl Deisseroth

Curr Opin Neurobiol. 2007 Oct;17(5):587-92.
Slice
(mouse hippocampus)
VSD
(RH-155)
MiCAM02
Differential dynamics of transient neuronal assemblies in visual compared to auditory cortex.

Subhojit Chakraborty, Anders Sandberg and Susan A. Greenfield

Exp Brain Res. 2007 Oct;182(4):491-8.
Slice
(rat cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice.

Isabelle Ferezou, Florent Haiss, Luc J. Gentet, Rachel Aronoff, Bruno Weber and Carl C.H. Petersen

Neuron. 2007 Dec 6;56(5):907-23. (Supplemental Data)
In Vivo
(Sensorimotor cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Optical and electrophysiological recordings of corticospinal synaptic activity and its developmental change in in vitro rat slice co-cultures.

Hitoshi Maeda, Takae Ohno and Masaki Sakurai

Neuroscience. 2007 Dec 19;150(4):829-40.
Slice
(rat spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM02
Gamma-band deficiency and abnormal thalamocortical activity in P/Q-type channel mutant mice.

Rodolfo R. Llinás, Soonwook Choi, Francisco J. Urbano and Hee-Sup Shin

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17819-24.
Slice
(mouse cortex)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Respiratory and metabolic acidosis differentially affect the respiratory neuronal network in the ventral medulla of neonatal rats.

Yasumasa Okada, Haruko Masumiya, Yoshiyasu Tamura and Yoshitaka Oku

Eur J Neurosci. 2007 Nov;26(10):2834-43.
Brainstem?spinal cordVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
Postnatal developmental changes in activation profiles of the respiratory neuronal network in the rat ventral medulla.

Yoshitaka Oku, Haruko Masumiya and Yasumasa Okada

J Physiol. 2007 Nov 15;585(Pt 1):175-86.
Brainstem?spinal cordVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
High-speed imaging reveals neurophysiological links to behavior in an animal model of depression.

Raag D. Airan, Leslie A. Meltzer, Madhuri Roy, Yuqing Gong, Han Chen and Karl Deisseroth

Science. 2007 Aug 10;317(5839):819-23.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Modafinil enhances thalamocortical activity by increasing neuronal electrotonic coupling.

Francisco J. Urbano, Elena Leznik and Rodolfo R. Llinas

Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12554-9.
Slice
(cortex)
VSD
(RH 414 or Di-4-ANEPPS)
MiCAM ULTIMA
Dynamics of neuronal assemblies are modulated by anaesthetics but not analgesics.

Collins TF, Mann EO, Hill MR, Dommett EJ, Greenfield SA.

Eur J Anaesthesiol. 2007 Jul;24(7):609-14.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors.

Sakura Nakauchi, Robert J. Brennan, Jim Boulter and Katsumi Sumikawa

Eur J Neurosci. 2007 May;25(9):2666-81.
Slice
(mouse hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM02
Combined voltage and calcium epifluorescence imaging in vitro and in vivo reveals subthreshold and suprathreshold dynamics of mouse barrel cortex.

Thomas Berger, Aren Borgdorff, Sylvain Crochet, Florian B. Neubauer, Sandrine Lefort, Bruno Fauvet, Isabelle Ferezou, Alan Carleton, Hans-Rudolf Lüscher and Carl C. H. Petersen

J Neurophysiol. 2007 Mar 14;
Xenopus oocytes

Slice (somatosensory cortex)

In Vivo (somatosensory cortex)
VSD
(RH-1691, Di-2-ANEPEQ)

CaSD
(OGB-1 AM)
MiCAM ULTIMA
GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.

Michiko Nakamura, Yuko Sekino and Toshiya Manabe

J Neurosci. 2007 Feb 7;27(6):1365-73.
Slice
(mouse hippocampus)
VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Wavelet-based multi-resolution statistics for optical imaging signals: Application to automated detection of odour activated glomeruli in the mouse olfactory bulb.

Brice Bathellier, Dimitri Van De Ville, Thierry Blu, Michael Unser and Alan Carleton

Neuroimage. 2007 Feb 1;34(3):1020-35. Epub 2006 Dec 19.
In Vivo
(mouse olfactory bulb)
Intrinsic signal
MiCAM ULTIMA
New field with tonotopic organization in Guinea pig auditory cortex.

Masataka Nishimura, Hiroshi Shirasawa, Hiroyuki Kaizo and Wen-Jie Song

J Neurophysiol. 2007 Jan;97(1):927-32. Epub 2006 Oct 18.
In Vivo
(Guinea pig auditory cortex)
VSD
(RH-795)
MiCAM ULTIMA
Imaging synaptosomal calcium concentration microdomains and vesicle fusion by using total internal reflection fluorescent microscopy.

Yafell Serulle, Mutsuyuki Sugimori and Rodolfo R. Llinas

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1697-702.
Squid optic lobe
Rat cerebellum
CaSD
(Calcium green-1)
MiCAM ULTIMA
Novel Axonal Projection from the Caudal End of the Ventrolateral Medulla to the Intermediolateral Cell Column.

Kamon Iigaya, Hiroo Kumagai, Hiroshi Onimaru, Akira Kawai, Naoki Oshima, Toshiko Onami, Chie Takimoto, Tadashi Kamayachi, Koichi Hayashi, Takao Saruta and Hiroshi Itoh

Am J Physiol Regul Integr Comp Physiol. 2006 Nov 2.
Brainstem-spinal cordVSD
(Di-2-ANEPEQ)
MiCAM01
Spontaneous oscillatory burst activity in the piriform-amygdala region and its relation to in vitro respiratory activity in newborn rats.

Hiroshi Onimaru and Ikuo Homma

Neuroscience. 2006 Oct 27.
Limbic?brainstem?spinal cord VSD
(Di-4-ANEPPS)
MiCAM01
Somatomotor and oculomotor inferior olivary neurons have distinct electrophysiological phenotypes.

Francisco J. Urbano, John I. Simpson and Rodolfo R. Llinas

Proc Natl Acad Sci U S A. 2006 Oct 18.
SliceVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
High pressure effects in anaesthesia and narcosis.

Agnieszka Wlodarczyk, Paul F. McMillan and Susan A. Greenfield

Chem. Soc. Rev., 2006, 35, 890-898.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Cortical intrinsic circuits can support activity propagation through an isofrequency strip of the guinea pig primary auditory cortex.

Wen-Jie Song, Hideo Kawaguchi, Shinichiro Totoki, Yuji Inoue, Takusige Katura, Shinichi Maeda, Shinji Inagaki, Hiroshi Shirasawa and Masataka Nishimura

Cereb Cortex. 2006 May;16(5):718-29.
Slice
(cortex)
VSD
(RH-795)
MiCAM ULTIMA
Ischemia-induced disturbance of neuronal network function in the rat spinal cord analyzed by voltage-imaging.

Kentaro Fukuda, Yasumasa Okada, Hideaki Yoshida, Ryoma Aoyama, Masaya Nakamura, Kazuhiro Chiba and Yoshiaki Toyama

Neuroscience. 2006 Jul 18;140(4):1453-65.
Slice
(spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM01
Layer-specific short-term dynamics in network activity in the cerebral cortex.

Michinori Kubota, Yutaka Hosokawa and Junsei Horikawa

Neuroreport. 2006 Jul 31;17(11):1107-1110.
Slice
(auditory cortex)
VSD
(Di-4-ANEPPS)
MiCAM01
Integration of evoked responses in supragranular cortex studied with optical recordings in vivo.

Eugene F. Civillico and Diego Contreras

J Neurophysiol. 2006 Jul;96(1):336-51. Epub 2006 Mar 29.
In Vivo
(cortex)
VSD
(RH-1691 and RH-795)
MiCAM01
Optical imaging of medullary ventral respiratory network during eupnea and gasping In situ.

Jeffrey T. Potts and Julian F. R. Paton

Eur J Neurosci. 2006 June;23(11):3025
In situ arterially perfused rat
(ventrolateral medulla)
VSD
(Di-2-ANEPEQ)
MiCAM02
Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice.

Isabelle Ferezou, Sonia Bolea and Carl C.H. Petersen

Neuron. 2006 May 18;50(4):617-29.
In Vivo
(barrel cortex)
VSD
(RH-1691)
MiCAM ULTIMA
Dopamine desynchronizes the pace-making neuronal activity of rat respiratory rhythm generation.

Morimitsu Fujii, Kazuo Umezawa and Akiko Arata

Eur J Neurosci. 2006 Feb;23(4):1015-27.
Medulla-spinal cord blockVSD
(Di-2-ANEPEQ)
MiCAM02
Hippocampus-mediated activation of superficial and deep layer neurons in the medial entorhinal cortex of the isolated guinea pig brain.

Vadym Gnatkovsky and Marco de Curtis

J Neurosci. 2006 Jan 18;26(3):873-81.
Isolated guinea pig brainVSD
(Di-2-ANEPEQ)
MiCAM01
A light-emitting diode light source for imaging of neural activities with voltage-sensitive dyes.

Masataka Nishimura, Hiroshi Shirasawa and Wen-Jie Song

Neuroscience Research. 2006 Jan 6
In VIvo
(auditory cortex)
VSD
(RH-795)
MiCAM ULTIMA
Comparison of responses to electrical stimulation and whisker deflection using two different voltage-sensitive dyes in mouse barrel cortex in vivo.

Civillico EF and Contreras D.

J Membr Biol. 2005 Nov;208(2):171-82.
In Vivo
(mouse barrel cortex)
VSD
(RH-1691)
MiCAM01
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.

Taisuke Mori, Tohru Kiyono, Hideaki Imabayashi, Yukiji Takeda, Kohei Tsuchiya, Shunichirou Miyoshi, Hatsune Makino, Kenji Matsumoto, Hirohisa Saito, Satoshi Ogawa, Michiie Sakamoto, Jun-Ichi Hata and Akihiro Umezawa

Molecular and Cellular Biology. 2005 Jun;25(12):5183-95.
Bone marrow stromal cellCaSD
(Fluo-3 AM)
MiCAM01
Optical imaging of respiratory neuron activity from the dorsal view of the lower brainstem.

Hiroshi Onimaru and Ikuo Homma

Clinical and Experimental Pharmacology and Physiology Apr;32(4):297-301.
Isolated brainstem-spinal cordVSD
(Di-4-ANEPPS or Di-2-ANEPEQ)
MiCAM01
Cholinergic modulation of the spatiotemporal pattern of hippocampal activity in vitro.

Edward O. Mann, Takashi Tominaga, Michinori Ichikawa and Susan A. Greenfield

Neuropharmacology. 2005 Jan;48(1):118-33.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Developmental changes in the spatio-temporal pattern of respiratory neuron activity in the medulla of late fetal rat.

Hiroshi Onimaru and Ikuo Homma

Neuroscience. 2005;131(4):969-77.
Isolated brainstem-spinal cordVSD
(Di-4-ANEPPS or Di-2-ANEPEQ)
MiCAM01
Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro.

Edward O. Mann, Jillian M. Suckling, Norbert Hajos, Susan A. Greenfield and Ole Paulsen

Neuron. 2005 Jan 6;45(1):105-117.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.

Fubito Nakatsu, Motohiro Okada, Fumiaki Mori, Noriko Kumazawa, Hiroto Iwasa, Gang Zhu, Yasufumi Kasagi, Haruyuki Kamiya, Akihiro Harada, Kazuhiro Nishimura, Arata Takeuchi, Taisuke Miyazaki, Masahiko Watanabe, Shigeki Yuasa, Toshiya Manabe, Koichi Wakabayashi, Sunao Kaneko, Takashi Saito and Hiroshi Ohno

J Cell Biol. 2004 Oct 25;167(2):293-302. Epub 2004 Oct 18.
Slice
(mouse hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
In vitro visualization of respiratory neuron activity in the newborn mouse ventral medulla.

Hiroshi Onimaru, Akiko Arata, Satoru Arata, Senji Shirasawa and Michael L. Cleary

Brain Res Dev Brain Res. 2004 Nov 25;153(2):275-9.
Isolated brainstem-spinal cordVSD
(Di-2-ANEPEQ)
MiCAM01
Optical recording of oscillatory neural activities in the molluscan brain.

Satoshi Watanabe, Satoshi Shimozono and Yutaka Kirino

Neurosci Lett. 2004 Apr 15;359(3):147-50.
Procerebrum
(slug)
VSD
(Di-4-ANEPPS)
MiCAM01
In vivo optical imaging of tone-evoked activity in the dorsal cochlear nucleus with a voltage sensitive dye.

James A Kaltenbach and Jinsheng Zhang

Journal of Neuroscience Research 2004 Volume 78, Issue 6, 908-917.
In Vivo
(hamster dorsal cochlear nucleus)
VSD
(Di-2-ANEPEQ)
MiCAM01
Purkinje cell functions in the in vitro cerebellum isolated from neonatal rats in a block with the pons and medulla.

Akiko Arata and Masao Ito.

Neuroscience Research 2004 Nov;50(3):361-367.
Cerebellum?pons?medulla block VSD
(Di-2-ANEPEQ)
MiCAM01
Optical mapping of pontine chemosensitive regions of neonatal rat.

Yoko Ito, Yoshitaka Oyamada, Yasumasa Okada, Haruhiko Hakuno, Ryoma Aoyama and Kazuhiro Yamaguchi

Neurosci Lett. 2004 Aug 5;366(1):103-6.
Isolated brainstem-spinal cordVSD
(Di-4-ANEPPS)
MiCAM01
In vivo fluorescence microscopy of neuronal activity in three dimension by use of voltage-sensitive dyes.

Jonathan AN Fisher, Eugene F Civillico, Diego Contreras and Arjun G Yodh.

Junuary 1, 2004/Vol.29(71-73), No.1/OPTICS LETTERS
In Vivo
(mouse barrel cortex)
VSD
(RH-795)
MiCAM01
Regulation of oxygen transport during brain activation: stimulus-induced hemodynamic responses inhuman and animal.

Akitoshi Seiyama, Junji Seki, Hiroki C Tanabe, Yasuhiro Ooi, Yasuhiko Satomura, Hisao Fujisaki and Toshio Yanagida.

Dyn Med. 2003 Dec 20;2(1):6.
In Vivo
(rat somatosensory cortex)
VSD
(Di-2-ANEPEQ)
MiCAM01
Synaptic Blockade Plays a Major Role in the Neural Disturbance of Experimental Spinal Cord Compression.

Hideaki Yoshida, Yasumasa Okada, Hirofumi Maruiwa, Kentaro Fukuda, Masaya Nakamura, Kazuhiro Chiba and Yoshiaki Toyama

J. Neurotrauma, Vol 20 (12), pp (2003)
Slice
(rat spinal cord)
VSD
(Di-4-ANEPPS)
MiCAM01
Activity-Dependent Depression of Excitability and Calcium Transients in the Neurohypophysis Suggests a Model of "Stuttering Conduction

Martin Muschol, Paul Kosterin, Michinori Ichikawa and B.M. Salzberg.

J. Neurosci. 2003 23: 11352-11362
NeurohypophysisVSD
(Di-2-ANEPEQ)
MiCAM ULTIMA
A Novel Functional Neuron Group for Respiratory Rhythm Generation in the Ventral Medulla.

Hiroshi Onimaru and Ikuo Homma.

J. Neurosci. 2003 23: 1478-1486
Isolated brainstem-spinal cordVSD
(Di-4-ANEPPS or Di-2-ANEPEQ)
MiCAM01
Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau.

Kentaro Tanemura, Miyuki Murayama, Takumi Akagi, Tsutomu Hashikawa, Takashi Tominaga, Michinori Ichikawa, Haruyasu Yamaguchi and Akihiko Takashima

J Neurosci. 2002 Jan 1;22(1):133-41.
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Optical Imaging of Long-Lasting Depolarization on Burst Stimulation in Area CA1 of Rat Hippocampal Slices.

Takashi Tominaga, Yoko Tominaga and Michinori Ichikawa

Journal of Neurophsiology (2002) 88:1523-1532
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Simulataneous multi-site recordings of neural activity with an inline multi-electrode array and optical measurement in rat hippocampal slices.

Yoko Tominaga, Michinori Ichikawa and Takashi Tominaga.

Europian Jounal of Physiolosy (2001) 443, 317-322
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01
Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex.

Takuji Iwasato, Akash Datwani, Alexander M. Wol3, Hiroshi Nishiyama, Yusuke Taguchi, Susumu Tonegawa, Thomas Knöpfel, Reha S. Erzurumlu and Shigeyoshi Itohara

Nature, 406, 726-731 (2000)
Slice
(mouse cortex)
VSD
(Di-4-ANEPPS)
MiCAM01
Quantification of optical signals with electorophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices.

Takashi Tominaga, Yoko Tominaga, Hitoshi Yamada, Gen Matsumoto and Michinori Ichikawa

Journal of Neuroscience Methods 102,11-23 (2000)
Slice
(rat hippocampus)
VSD
(Di-4-ANEPPS)
MiCAM01

単離心臓論文 

合計:244

論文名サンプル色素イメージングシステム
Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes.

Duanyang Xie, Ke Xiong, Xuling Su, Guanghua Wang, Qiang Ji, Qicheng Zou, Lingling Wang, Yi Liu, Dandan Liang, Jinfeng Xue, Luxin Wang, Xueting Gao, Xingdong Gu, Hongyu Liu, Xiaoyu He, Li Li, Jian Yang, Youming Lu, Luying Peng & Yi-Han Chen

Cell Research volume 31, pages951?964 (2021)
Isolated heartVSD
(RH-237)
MiCAM ULTIMA
α1-adrenergic stimulation increases ventricular action potential duration in the intact mouse heart.

William Joyce, Koen T. Scholman, Bjarke Jensen, Tobias Wang, and Bastiaan J. Boukens

FACETS. 6(): 823-836.
Isolated heartVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Proinflammatory Cytokine Modulates Intracellular Calcium Handling and Enhances Ventricular Arrhythmia Susceptibility.

Yung-Nan Tsai, Ya-Wen Hsiao, Shien-Fong Lin, Yi-Hsin Chan, Yu-Cheng Hsieh, Wei-Hua Tang, An-Sheng Lee, Yu-Ting Huang, Hsing-Yuan Li, Tze-Fan Chao, Satoshi Higa, Tsu-Juey Wu, Shih-Lin Chang, Shih-Ann Chen

Front Cardiovasc Med. 2021 Mar 16;8:623510.
Isolated heartVSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM02
(dual camera)
Adult zebrafish ventricular electrical gradients as tissue mechanisms of ECG patterns under baseline vs. oxidative stress.

Yali Zhao, Nicholas A James, Ashraf R Beshay, Eileen E Chang, Andrew Lin, Faiza Bashar, Abram Wassily, Binh Nguyen, Thao P Nguyen

Cardiovasc Res. 2021 Jul 7;117(8):1891-1907.
Isolated heart
(zebrafish)
VSD
(Di-4-ANEPPS)
MiCAM03
Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models.

Fumin Fu, Michael Pietropaolo, Lei Cui, Shilpa Pandit, Weiyan Li, Oleg Tarnavski, Suraj S. Shetty, Jing Liu, Jennifer M. Lussier, Yutaka Murakami, Prabhjit K. Grewal, Galina Deyneko, Gordon M. Turner, Andrew K.P. Taggart, M. Gerard Waters, Shaun Coughlin, Yuichiro Adachi

bioRxiv 2021.08.17.456655;
Isolated heartVSD
(Di-4-ANEPPS)
MiCAM03
High Level of Real Urban Air Pollution Promotes Cardiac Arrhythmia in Healthy Mice.

Hyewon Park, Sangchul Lim, Seunghoon Lee, Dasom Mun, JiYoung Kang, Hyoeun Kim, Hyelim Park, Changsoo Kim, Sunho Park, Yeong Min Lim, Boyoung Joung

Korean Circ J. 2021 Feb;51(2):157-170.
Isolated heartVSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Adherens junction engagement regulates functional patterning of the cardiac pacemaker cell lineage.

Kandace Thomas, Trevor Henley, Simone Rossi, M Joseph Costello, William Polacheck, Boyce E Griffith, Michael Bressan

Dev Cell. 2021 May 17;56(10):1498-1511.e7.
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)

CaSD
(Cal-520)
MiCAM ULTIMA
Theoretical Models and Computational Analysis of Action Potential Dispersion for Cardiac Arrhythmia Risk Stratification.

Uma Mahesh R. Avula, Lea Melki, Jared S. Kushner, Stephanie Liang, and Elaine Y. Wan

Front Cardiovasc Med. 2021; 8: 649489.
Isolated heartVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart.

Lianguo Wang, Rachel C. Myles, I-Ju Lee, Donald M. Bers, and Crystal M. Ripplinger

Front Physiol. 2021; 12: 656516.
Isolated heartVSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.

Yeon Sik Choi, Rose T Yin, Anna Pfenniger, Jahyun Koo, Raudel Avila, K Benjamin Lee, Sheena W Chen, Geumbee Lee, Gang Li, Yun Qiao, Alejandro Murillo-Berlioz, Alexi Kiss, Shuling Han, Seung Min Lee, Chenhang Li, Zhaoqian Xie, Yu-Yu Chen, Amy Burrell, Beth Geist, Hyoyoung Jeong, Joohee Kim, Hong-Joon Yoon, Anthony Banks, Seung-Kyun Kang, Zheng Jenny Zhang, Chad R Haney, Alan Varteres Sahakian, David Johnson, Tatiana Efimova, Yonggang Huang, Gregory D Trachiotis, Bradley P Knight, Rishi K Arora, Igor R Efimov, John A Rogers

Nat Biotechnol. 2021 Jun 28.
Isolated heartVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Flexible and Transparent Metal Nanowire Microelectrode Arrays and Interconnects for Electrophysiology, Optogenetics, and Optical Mapping.

Zhiyuan Chen, Nicolas Boyajian, Zexu Lin, Rose T. Yin, Sofian N. Obaid, Jinbi Tian, Jaclyn A. Brennan, Sheena W. Chen, Alana N. Miniovich, Leqi Lin, Yarong Qi, Xitong Liu, Igor R. Efimov, Luyao Lu

Adv. Mater. Technol. 2021, 6, 2100225.
Isolated heartVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia.

Ge Zhan, Fang Wang, Yun-qi Ding, Xiang-hua Li, Yue-xin Li, Zheng-rong Zhao, Jia-xin Li, Yan Liu, Xin Zhao, Cai-chuan Yan, Bao-xin Li

J Cell Mol Med. 2021;00:1?12.
Isolated heartVSD
(RH-237)
MiCAM05
Knockout of interleukin-17A diminishes ventricular arrhythmia susceptibility in diabetic mice via inhibiting NF-κB-mediated electrical remodeling.

De-sheng Li, Gen-long Xue, Ji-ming Yang, Chang-zhu Li, Rui-xin Zhang, Tao Tian, Zheng Li, Ke-wei Shen, Yang Guo, Xue-ning Liu, Jin Wang, Yan-jie Lu & Zhen-wei Pan

Acta Pharmacologica Sinica (2021)
Isolated heartVSD
(RH-237)
MiCAM05
Anti-arrhythmic and inotropic effects of empagliflozin following myocardial ischemia.

Mohammed Ali Azam, Praloy Chakraborty, Daoyuan Si, BeiBei Du, Stéphane Massé, Patrick F H Lai, Andrew C T Ha, Kumaraswamy Nanthakumar

Life Sci. 2021 Jul 1;276:119440.
Isolated heartCaSD
(Rhod-2 AM)
MiCAM ULTIMA
NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias.

Larry Scott Jr, Anke C Fender, Arnela Saljic, Luge Li, Xiaohui Chen, Xiaolei Wang, Dominik Linz, Jilu Lang, Mathias Hohl, Darragh Twomey, Thuy T Pham, Rodrigo Diaz-Lankenau, Mihail G Chelu, Markus Kamler, Mark L Entman, George E Taffet, Prashanthan Sanders, Dobromir Dobrev, Na Li

Cardiovasc Res. 2021 Jun 16;117(7):1746-1759.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Minimally invasive system to reliably characterize ventricular electrophysiology from living donors.

Aida Oliván-Viguera, María Pérez-Zabalza, Laura García-Mendívil, Konstantinos A. Mountris, Sofía Orós-Rodrigo, Estel Ramos-Marquès, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Fernando Sorribas-Berjón, Javier André Bellido-Morales, Francisco Javier Mancebón-Sierra, Alexánder Sebastián Vaca-Núñez, Carlos Ballester-Cuenca, Miguel Ángel Marigil, Cristina Pastor, Laura Ordovás, Ralf Köhler, Emiliano Diez & Esther Pueyo

Scientific Reports volume 10, Article number: 19941 (2020).
Tissue slice
(human)
VSD
(RH-237)
MiCAM05
Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation.

Yan Liu, Xueqi Xu, Yuhao Zhang, Mingzhu Li, Jiamengyi Guo, Caichuan Yan, Fang Wang, Yuexin Li, Yunqi Ding, Baoxin Li, and Pan Fan

Oxidative Medicine and Cellular Longevity, vol. 2020, Article ID 3690123, 17 pages, 2020.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Identification of transmembrane protein 168 mutation in familial Brugada syndrome.

Akio Shimizu, Dimitar P Zankov, Akira Sato, Masahiro Komeno, Futoshi Toyoda, Satoru Yamazaki, Toshinori Makita, Taichi Noda, Masahito Ikawa, Yoshihiro Asano, Yohei Miyashita, Seiji Takashima, Hiroshi Morita, Taisuke Ishikawa, Naomasa Makita, Masahito Hitosugi, Hiroshi Matsuura, Seiko Ohno, Minoru Horie, Hisakazu Ogita

FASEB J. 2020 May;34(5):6399-6417.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM03
Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas.

Peter Hanna, Michael J. Dacey, Jaclyn Brennan, Alison Moss, Shaina Robbins, Sirisha Achanta, Natalia P. Biscola, Mohammed A. Swid, Pradeep S. Rajendran, Shumpei Mori, Joseph E. Hadaya, Elizabeth H. Smith, Stanley G. Peirce, Jin Chen, Leif A. Havton, Zixi (Jack) Cheng, Rajanikanth Vadigepalli, James Schwaber, Robert L. Lux, Igor Efimov, John D. Tompkins, Donald B. Hoover, Jeffrey L. Ardell, Kalyanam Shivkumar

bioRxiv 2020.10.28.359109.
SAN/atria preparation
(human)
VSD
(Di-4-ANEPPS)
MiCAM05
Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding?deficient channels.

Jeffrey Abrams, Daniel Roybal, Nourdine Chakouri, Alexander N. Katchman, Richard Weinberg, Lin Yang, Bi-xing Chen, Sergey I. Zakharov, Jessica A. Hennessey, Uma Mahesh R. Avula, Johanna Diaz, Chaojian Wang, Elaine Y. Wan, Geoffrey S. Pitt, Manu Ben-Johny, and Steven O. Marx

JCI Insight. 2020 Oct 2; 5(19): e141736.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells.

Stefanie Fenske, Konstantin Hennis, René D. Rötzer, Verena F. Brox, Elvir Becirovic, Andreas Scharr, Christian Gruner, Tilman Ziegler, Verena Mehlfeld, Jaclyn Brennan, Igor R. Efimov, Audrys G. Pauža, Markus Moser, Carsten T. Wotjak, Christian Kupatt, Rasmus Gönner, Rai Zhang, Henggui Zhang, Xiangang Zong, Martin Biel and Christian Wahl-Schott

Nat Commun. 2020; 11: 5555.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM05
The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unresponsive to standard heart failure therapy.

Tim R. Eijgenraam, Bastiaan J. Boukens, Cornelis J. Boogerd, E. Marloes Schouten, Cees W. A. van de Kolk, Nienke M. Stege, Wouter P. te Rijdt, Edgar T. Hoorntje, Paul A. van der Zwaag, Eva van Rooij, J. Peter van Tintelen, Maarten P. van den Berg, Peter van der Meer, Jolanda van der Velden, Herman H. W. Silljé & Rudolf A. de Boer

Scientific Reports volume 10, Article number: 9819 (2020)
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM05
Anti-Inflammatory and Antiarrhythmic Effects of Beta Blocker in a Rat Model of Rheumatoid Arthritis.

Ting-Tse Lin, Yen-Ling Sung, Jhen-Yang Syu, Kia-Yuan Lin, Hung-Jui Hsu, Min-Tsun Liao, Yen-Bin Liu, Shien-Fong Lin

J Am Heart Assoc. 2020 Sep 15;9(18):e016084.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats.

Beibei Du, Praloy Chakraborty, Mohammed Ali Azam, Stéphane Massé, Patrick F.H. Lai, Ahmed Niri BEng, Daoyuan Si, Paaladinesh Thavendiranathan, Husam Abdel-Qadir, Filio Billia, Kumaraswamy Nanthakumar

JACC: CardioOncology Volume 2, Issue 4, November 2020, Pages 614-629
Isolated heart
(rat)
VSD
RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Reverse electromechanical modelling of diastolic dysfunction in spontaneous hypertensive rat after sacubitril/valsartan therapy.

Yen]Ling Sung, Ting]Tse Lin, Jhen]Yang Syu, Hung]Jui Hsu, Kai]Yuan Lin, Yen]Bin Liu, Shien]Fong Lin

ESC Heart Failure 2020; 7: 4040?4050
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix.

Jiyoung Lee, Akito Sutani, Rin Kaneko, Jun Takeuchi, Tetsuo Sasano, Takashi Kohda, Kensuke Ihara, Kentaro Takahashi, Masahiro Yamazoe, Tomohiro Morio , Tetsushi Furukawa, Fumitoshi Ishino

Nat Commun. 2020 Sep 3;11(1):4283.
OrganoidVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
The sodium channel NaV1.5 impacts on early murine embryonic cardiac development, structure and function in a non]electrogenic manner.

Gerard A. Marchal, Arie O. Verkerk, Rajiv A. Mohan, Rianne Wolswinkel, Bastiaan J. D. Boukens, and Carol Ann Remme

Acta Physiol (Oxf). 2020 Oct; 230(2): e13493.
Isolated heart
(mouse embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Sacubitril/Valsartan Therapy Ameliorates Ventricular Tachyarrhythmia Inducibility in a Rabbit Myocardial Infarction Model.

Po-Cheng Chang, Hung-Ta Wo, Hui-Ling Lee, Shien-Fong Lin, Yen Chu, Ming-Shien Wen, Chung-Chuan Chou

J Card Fail. 2020 Jun;26(6):527-537.
Isolated heart
(rabbit)
VSD
RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Single Bolus Rosuvastatin Accelerates Calcium Uptake and Attenuates Conduction Inhomogeneity in Failing Rabbit Hearts With Regional Ischemia-Reperfusion Injury.

Chung-Chuan Chou, Hui-Ling Lee, Yu-Chang Huang, Hung-Ta Wo, Ming-Shien Wen, Yen Chu, Po-Cheng Chang

J Cardiovasc Pharmacol. 2020 Jan;75(1):64-74.
Isolated heart
(rabbit)
VSD
RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity.

Matthias Baudot, Eleonora Torre, Isabelle Bidaud, Julien Louradour, Angelo G. Torrente, Lucile Fossier, Leïla Talssi, Joël Nargeot, Stéphanie Barrère-Lemaire, Pietro Mesirca, and Matteo E. Mangoni

Sci Rep. 2020; 10: 18906.
SAN/atria preparation
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Mechanisms of ranolazine pretreatment in preventing ventricular tachyarrhythmias in diabetic db/db mice with acute regional ischemia-reperfusion injury.

Chung-Chuan Chou, Hui-Ling Lee, Gwo-Jyh Chang, Hung-Ta Wo, Tzung-Hai Yen, Ming-Shien Wen, Yen Chu, Hao-Tien Liu, Po-Cheng Chang

Sci Rep. 2020 Nov 18;10(1):20032.
Isolated heart
(mouse)
VSD
RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Preclinical Cardiac Electrophysiology Assessment by Dual Voltage and Calcium Optical Mapping of Human Organotypic Cardiac Slices.

Sharon A George, Jaclyn A Brennan, Igor R Efimov

J Vis Exp. 2020 Jun 16;(160). doi: 10.3791/60781.
Tissue slice
(human)
VSD
RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Stretchable Conductive Fabric for Cardiac Electrophysiology Applications.

Angel Moreno, Richard D. Walton, and Jason D. Bayer

ACS Appl. Bio Mater. 2020, 3, 5, 3114?3122
Isolated heart
(rig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation.

Young M Kim, Robert Lakin, Hao Zhang, Jack Liu, Ayaaz Sachedina, Maneesh Singh, Emily Wilson, Marco Perez, Subodh Verma, Thomas Quertermous, Jeffrey Olgin, Peter H Backx, Euan A Ashley

JCI Insight. 2020 Sep 3;5(17):e126525.
Isolated atria
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Mechanical stimulation of endocardial Purkinje fibres can trigger ventricular arrhythmias.

Ed White, Richard Walton, Sarbjot Kaur, Amelia Power, Michel Haïssaguerre, Olivier Bernus, Marie-Louise Ward

bioRxiv 2020.08.10.234195
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Attenuating loss of cardiac conduction during no-flow ischemia through changes in perfusate sodium and calcium.

Gregory S Hoeker, Carissa C James, Allison N Tegge, Robert G Gourdie, James W Smyth, Steven Poelzing

Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H396-H409.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.

Wenli Dai, Rangarajan D. Nadadur, Jaclyn A. Brennan, Heather L. Smith, Kaitlyn M. Shen, Margaret Gadek, Brigitte Laforest, Mingyi Wang, Joanna Gemel, Ye Li, Jing Zhang, Bruce D. Ziman, Jiajie Yan, Xun Ai, Eric C. Beyer, Edward G. Lakata, Narayanan Kasthuri, Igor R. Efimov, Michael T. Broman, Ivan P. Moskowitz, Le Shen, Christopher R. Weber

Circulation Research. 2020;127:e28?e43
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Effects of high-frequency biphasic shocks on ventricular vulnerability and defibrillation outcomes through synchronized virtual electrode responses.

Yu-An Chiou, Li-Kuan Cheng, Shien-Fong Lin

PLoS One. 2020; 15(5): e0232529.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Connexin43 expression in bone marrow derived cells contributes to the electrophysiological properties of cardiac scar tissue.

Carolina Vasquez, Valeria Mezzano, Newman Kessler, Freja Swardh, Desiree Ernestad, Vanessa M. Mahoney, John Hanna & Gregory E. Morley

Scientific Reports volume 10, Article number: 2617 (2020)
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling.

Louisa Mezache, Heather L. Struckman, Amara Greer-Short, Stephen Baine, Sándor Györke, Przemysław B. Radwański, Thomas J. Hund and Rengasayee Veeraraghavan

Sci Rep. 2020; 10: 20463.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss.

Srinivas Tapa, Lianguo Wang, Samantha D. Francis Stuart, Zhen Wang, Yanyan Jiang, Beth A. Habecker & Crystal M. Ripplinger

Scientific Reports volume 10, Article number: 18801 (2020)
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Aging Disrupts Normal Time-of-Day Variation in Cardiac Electrophysiology.

Zhen Wang, Srinivas Tapa, Samantha D Francis Stuart, Lianguo Wang, Julie Bossuyt, Brian P Delisle, Crystal M Ripplinger

Circ Arrhythm Electrophysiol. 2020 Sep;13(9):e008093.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Optical Mapping-Validated Machine Learning Improves Atrial Fibrillation Driver Detection by Multi-Electrode Mapping.

Alexander M Zolotarev, Brian J Hansen, Ekaterina A Ivanova, Katelynn M Helfrich, Ning Li, Paul M L Janssen, Peter J Mohler, Nahush A Mokadam, Bryan A Whitson, Maxim V Fedorov, John D Hummel, Dmitry V Dylov, Vadim V Fedorov

Circ Arrhythm Electrophysiol. 2020 Oct;13(10):e008249.
Isolated atria
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels.

Duanyang Xie, Li Geng, Shuo Wang, Ke Xiong, Tingting Zhao, Guanghua Wang, Zhiqiang Feng, Fei Lv, Cheng Wang, Dandan Liang, Dan ShiMD, Xiue MaMD, Yi Liu, Jian Yang, Chao Zhang, Yi-Han Chen

Heart Rhythm Volume 17, Issue 6, June 2020, Pages 998-1008
Isolated heart
(rat)
VSD
(RH-237)
MiCAM ULTIMA
What Is the Optimal Light Source for Optical Mapping Using Voltage- and Calcium-Sensitive Dyes?

V Olejnickova, D Sedmera

Physiol Res. 2020 Aug 31;69(4):599-607
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction.

Lianguo Wang, Antoinette Olivas, Samantha D Francis Stuart, Srinivas Tapa, Matthew R Blake, William R Woodward, Beth A Habecker, Crystal M Ripplinger

Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H558-H565.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Evidence of Superior and Inferior Sinoatrial Nodes in the Mammalian Heart.

Jaclyn A. Brennan, Qing Chen, Anna Gams, Jhansi Dyavanapalli, David Mendelowitz, Weiqun Peng, Igor R.Efimov

JACC Clin Electrophysiol. 2020 Dec;6(14):1827-1840.
Isolated atrium
(human)
VSD
(Di-4-ANEPPS)
MiCAM05
Sudden Heart Rate Reduction Upon Optogenetic Release of Acetylcholine From Cardiac Parasympathetic Neurons in Perfused Hearts.

Angel Moreno, Kendal Endicott, Matthew Skancke, Mary Kate Dwyer, Jaclyn Brennan, Igor R. Efimov, Gregory Trachiotis, David Mendelowitz, and Matthew W. Kay

Front Physiol. 2019 Sep 4;10:1105.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation.

Jason D. Bayer, Bastiaan J. Boukens, Sébastien P. J. Krul, Caroline H. Roney, Antoine H. G. Driessen, Wouter R. Berger, Nicoline W. E. van den Berg, Arie O. Verkerk, Edward J. Vigmond, Ruben Coronel, and Joris R. de Groot

Front Physiol. 2019 Sep 4;10:1105.
Atrial appendage preparation
(human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Caveolae]Mediated Activation of Mechanosensitive Chloride Channels in Pulmonary Veins Triggers Atrial Arrhythmogenesis.

Yuriy V. Egorov, Di Lang, Leonid Tyan, Daniel Turner, Evi Lim, Zachary D. Piro, Jonathan J. Hernandez, Rylie Lodin, Rose Wang, Eric G. Schmuck, Amish N. Raval, Carter J. Ralphe, Timothy J. Kamp, Leonid V. Rosenshtraukh, and Alexey V. Glukhov

Sci Rep. 2019; 9: 7502.
Pulmonary vein preparation
(rat)
VSD
(RH-237)
MiCAM ULTIMA
Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12.

Zhenwei Pan, Tomohiko Ai, Po-Cheng Chang, Ying Liu, Jijia Liu, Mitsunori Maruyama, Mohamed Homsi, Michael C. Fishbein, Michael Rubart, Shien-Fong Lin, Deyong Xiao, Hanying Chen, Peng-Sheng Chen, Weinian Shou and Bai-Yan Li

Am J Physiol Heart Circ Physiol. 2019 Feb 1; 316(2): H371?H379.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Inhibition of PI3Kinase-α is pro-arrhythmic and associated with enhanced late Na+ current, contractility, and Ca2+ release in murine hearts.

Pavel Zhabyeyev, Brent McLean, Xueyi Chen, Bart Vanhaesebroeck, Gavin Y. Oudit

Theranostics. 2019; 9(24): 7222?7238.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice.

Satsuki Sato, Jinya Suzuki, Masamichi Hirose, Mika Yamada, Yasuo Zenimaru, Takahiro Nakaya, Mai Ichikawa, Michiko Imagawa, Sadao Takahashi, Shoichiro Ikuyama, Tadashi Konoshita, Fredric B Kraemer, Tamotsu Ishizuka

Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E1193-E1204.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM02
Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model.

Tae Yun Kim, Paul Jeng, JungMin Hwang, Zachary Pfeiffer, Divyang Patel, Leroy L Cooper, Konstantinos Kossidas, Jason Centracchio, Xuwen Peng, Gideon Koren, Zhilin Qu, Bum-Rak Choi

Sci Rep. 2019 Oct 16;9(1):14849.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts.

Shanna Hamilton, Iuliia Polina, Radmila Terentyeva, Peter Bronk, Tae Yun Kim, Karim Roder, Richard T Clements, Gideon Koren, Bum-Rak Choi, Dmitry Terentyev

J Physiol. 2020 Jul;598(14):2847-2873.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function.

Joshua W Vincentz, Beth A Firulli, Kevin P Toolan, Dan E Arking, Nona Sotoodehnia, Juyi Wan, Peng-Sheng Chen, Corrie de Gier-de Vries, Vincent M Christoffels, Michael Rubart-von der Lohe, Anthony B Firulli

Circ Res. 2019 Aug 30;125(6):575-589.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Absence of natriuretic peptide clearance receptor attenuates TGF-β1-induced selective atrial fibrosis and atrial fibrillation.

Dolkun Rahmutula, Hao Zhang, Emily E Wilson, Jeffrey E Olgin

Cardiovasc Res. 2019 Feb 1;115(2):357-372.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling.

Brian Martin, Beth Gabris, Amr F. Barakat, Brian L. Henry, Marianna Giannini, Rajiv P. Reddy, Xuewen Wang, Guillermo Romero & Guy Salama

Scientific Reports volume 9, Article number: 18545 (2019)
Isolated heart
(rat)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Heterogeneity of the action potential duration is required for sustained atrial fibrillation.

Uma Mahesh R. Avula, Jeffrey Abrams, Alexander Katchman, Sergey Zakharov, Sergey Mironov, Joseph Bayne, Daniel Roybal, Anirudh Gorti, Lin Yang, Vivek Iyer, Marc Waase, Deepak Saluja, Edward J. Ciaccio, Hasan Garan, Andrew R. Marks, Steven O. Marx, and Elaine Y. Wan

JCI Insight. 2019 Apr 25;5(11):e128765.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice.

Simona Casini, Maxime Albesa, Zizun Wang, Vincent Portero, Daniela Ross-Kaschitza, Jean-Sébastien Rougier, Gerard A. Marchal, Wendy K. Chung, Connie R. Bezzina, Hugues Abriel, and Carol Ann Remme

Int J Mol Sci. 2019 Oct; 20(20): 5033.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Wide-area low-energy surface stimulation of large mammalian ventricular tissue.

Angel Moreno, Richard D Walton, Marion Constantin, Olivier Bernus, Edward J Vigmond, Jason D Bayer

Front Physiol. 2019 Feb 26;10:146.
Ventricular wedge preparation
(pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optical Imaging of Ventricular Action Potentials in a Torso Tank: A New Platform for Non-Invasive Electrocardiographic Imaging Validation.

Laura R Bear, Richard D Walton, Emma Abell, Yves Coudière, Michel Haissaguerre, Olivier Bernus, Rémi Dubois

Front Physiol. 2019 Feb 26;10:146.
Isolated heart
(pig)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models.

Philipp Gutruf, Rose T Yin, K Benjamin Lee, Jokubas Ausra, Jaclyn A Brennan, Yun Qiao, Zhaoqian Xie, Roberto Peralta, Olivia Talarico, Alejandro Murillo, Sheena W Chen, John P Leshock, Chad R Haney, Emily A Waters, Changxing Zhang, Haiwen Luan, Yonggang Huang, Gregory Trachiotis, Igor R Efimov, John A Rogers

Nat Commun. 2019 Dec 17;10(1):5742.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Simplified platform for mosaic in vivo analysis of cellular maturation in the developing heart.

Julie Goudy, Trevor Henley, Hernán G. Méndez and Michael Bressan

Scientific Reports volume 9, Article number: 10716 (2019)
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Inhibition of soluble TNFα prevents adverse atrial remodeling and atrial arrhythmia susceptibility induced in mice by endurance exercise.

Robert Lakin, Nazari Polidovitch, Sibao Yang, Camilo Guzman, Xiaodong Gao, Marianne Wauchop, Jacob Burns, Farzad Izaddoustdar, Peter H Backx

J Mol Cell Cardiol. 2019 Apr;129:165-173.
Isolated atria
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts.

Lianguo Wang, Stefano Morotti, Srinivas Tapa, Samantha D Francis Stuart, Yanyan Jiang, Zhen Wang, Rachel C Myles, Kieran E Brack, G André Ng, Donald M Bers, Eleonora Grandi, Crystal M Ripplinger

J Physiol. 2019 Aug;597(15):3867-3883.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo.

Tanner O Monroe, Matthew C Hill, Yuka Morikawa, John P Leach, Todd Heallen, Shuyi Cao, Peter H L Krijger, Wouter de Laat, Xander H T Wehrens, George G Rodney, James F Martin

Dev Cell. 2019 Mar 25;48(6):765-779.e7.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model.

Zhen Wang, Lianguo Wang, Srinivas Tapa, Kent E. Pinkerton, Chao-Yin Chen and Crystal M. Ripplinger

Environmental Health Perspectives. 126(12) December 2018
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Ventricular Endocardial Tissue Geometry Affects Stimulus Threshold and Effective Refractory Period.

Adam Connolly, Allen Kelly, Fernando O. Campos, Rachel Myles, Godfrey Smith and Martin J. Bishop

Biophys J. 2018 Dec 18;115(12):2486-2498.
Ventricular wedge preparation
(rabbit)
VSD
(RH-237)
MiCAM ULTIMA
Critical Volume of Human Myocardium Necessary to Maintain Ventricular Fibrillation.

Kedar K. Aras, Ndeye Rokhaya Faye, Brianna Cathey and Igor R. Efimov

Circ Arrhythm Electrophysiol. 2018 Nov;11(11):e006692.
Ventricular wedge preparation
(human)
VSD
(Di-4-ANBDQBS)
MiCAM05
(quad camera)
Arrhythmogenic Remodeling of the Left Ventricle in a Porcine Model of Repaired Tetralogy of Fallot.

Virginie Dubes, David Benoist, François Roubertie, Stephen H. Gilbert, Marion Constantin, Sabine Charron, Delphine Elbes, Delphine Vieillot, Bruno Quesson, Hubert Cochet, Michel Haïssaguerre, Caroline Rooryck, Pierre Bordachar, Jean-Benoit Thambo, and Olivier Bernus

Circ Arrhythm Electrophysiol. 2018;11:e006059.
Ventricular wedge preparation
(pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling.

Yong Zhang, Lihua Sun, Lina Xuan, Zhenwei Pan, Xueling Hu, Hongyu Liu, Yunlong Bai, Lei Jiao, Zhange Li, Lina Cui, Xiaoxue Wang, Siqi Wang, Tingting Yu, Bingbing Feng, Ying Guo, Zonghong Liu, Weixin Meng, Hequn Ren, Jiyuan Zhu, Xuyun Zhao, Chao Yang, Ying Zhang, Chaoqian Xu, Zhiguo Wang, Yanjie Lu, Hongli Shan, and Baofeng Yang

Nat Commun. 2018 Oct 9;9(1):4176.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM05
CRISPR]Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.

Paul D. Pang, Katherina M. Alsina, Shuyi Cao, Amrita B. Koushik, Xander H.T. Wehrens and Thomas A. Cooper

J Am Heart Assoc. 2018;7:e010393.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, and Samuel C. Dudley Jr.

Heart Rhythm. 2018 Jul;15(7):1072-1080.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium.

Marine E. Martinez, Richard D. Walton, Jason D. Bayer, Michel Haïssaguerre, Edward J. Vigmond, Mélèze Hocini and Olivier Bernus

Front Physiol. 2018 Jun 14;9:718.
Ventricular wedge preparation
(sheep)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Small-conductance Ca2+-activated K+ channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy.

Taro Tenma, Hirofumi Mitsuyama, Masaya Watanabe, Naoya Kakutani, Yutaro Otsuka, Kazuya Mizukami, Rui Kamada, Masayuki Takahashi, Shingo Takada, Hisataka Sabe, Hiroyuki Tsutsui, and Hisashi Yokoshiki

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H262-H272.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM02
Absence of NPR-C Attenuates TGF-s1 Induced Selective Atrial Fibrosis and Atrial Fibrillation.

Dolkun Rahmutula, Hao Zhang, Emily E Wilson and Jeffrey E Olgin

Cardiovasc Res. 2018 Sep 18.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Essential Role of RyR2 Phosphorylation in the Effect of Azumolene on Ventricular Arrhythmia Vulnerability in a Rabbit Heart Model.

Daoyuan Si, Mohammed Ali Azam, Patrick F.H. Lai, Nima Zamiri, Galina Kichigina, John Asta, Stéphane Massé, Mahmoud M. Bokhari, Andreu Porta]Sánchez, Christopher Labos, Huan Sun, Ping Yang and Kaumaraswamy Nanthakumar

J Cardiovasc Electrophysiol. 2018 Sep 11.
Isolated heart
(rabbit)
CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Apoptosis and epicardial contributions act as complementary factors in remodeling of the atrioventricular canal myocardium and atrioventricular conduction patterns in the embryonic chick heart.

Rebecca Vicente Steijn, David Sedmera, Nico A. Blom, Monique Jongbloed, Alena Kvasilova, and Ondrej Nanka

Dev Dyn. 2018 Sep;247(9):1033-1042.
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Effects of long-term exercise on arrhythmogenesis in aged hypertensive rats.

Yen-Ling Sung, Chih-En Wu, Jhen-Yang Syu,Terry B.J.Kuo, Jai-YiLi, Chieh-Wen Chen, Ching-Hui Weng, Wei-Hsuan Hsu, Shih-Ann Chen, Yu-Feng Hu and Shien-Fong Lin

Comput Biol Med. 2018 Aug 16. pii: S0010-4825(18)30236-1.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Compartmentalized Structure of the Moderator Band Provides a Unique Substrate for Macroreentrant Ventricular Tachycardia.

Richard D. Walton, Ali Pashaei, Marine E. Martinez, Marion Constantin, Josselin Duchateau, Laura Bear, Caroline Cros, Caroline Pascarel-Auclerc, Yunbo Guo, David Benoist, Virginie Dubes, Ndeye Rokhaya Faye, Sebastien Chaigne, Sebastien Dupuis, Dominique Détaille, Line Pourtau, Philippe Pasdois, Fabien Brette, Julien Rogier, Louis Labrousse, Mélèze Hocini, Edward J. Vigmond, Michel Haïssaguerre and Olivier Bernus

Circulation: Arrhythmia and Electrophysiology. 2018;11:e005913
Ventricular wedge preparation
(sheep, human)
VSD
(Di]4]ANBDQBS)
MiCAM ULTIMA
CaMKII-dependent late Na+ current increases electrical dispersion and arrhythmia in ischemia-reperfusion.

Taylor Howard, Amara Greer-Short, Tony Satroplus, Nehal Patel, Drew Nassal, Peter J. Mohler, and Thomas J. Hund

Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H794-H801.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM05
LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction.

Ying Zhang, Lei Jiao, Lihua Sun, Yanru Li, Yuqiu Gao, Chaoqian Xu, Yingchun Shao, Mengmeng Li, Chunyan Li, Yanjie Lu, Zhenwei Pan, Lina Xuan, Yiyuan Zhang, Qingqi Li, Rui Yang, Yuting Zhuang, Yong Zhang and Baofeng Yang

Circ Res. 2018 May 11; 122(10): 1354?1368.
Isolated heart
(mouse)
CaSD
(Rhod-2 AM)
MiCAM05
Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.

Samantha D. Francis Stuart, Lianguo Wang, William R. Woodard, G. Andre Ng, Beth A. Habecker and Crystal M. Ripplinger

J Physiol. 2018 Jun 25.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility.

Diana C. Parrish, Samantha D. Francis Stuart, Antoinette Olivas, Lianguo Wang, Anders Nykjaer, Crystal M. Ripplinger, and Beth A. Habecker

Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H415-H423.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, Samuel C. Dudley Jr.

Heart Rhythm. 2018 Feb 16.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy.

Qiongling Wang, Ann P. Quick, Shuyi Cao, Julia Reynolds, David Y. Chiang, David Beavers, Na Li, Guoliang Wang, George G. Rodney, Mark E. Anderson, Xander H.T. Wehrens.

Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005682.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Ondansetron Blocks Wildtype and p.F503L Variant Small Conductance Calcium Activated Potassium Channels.

Jum-Suk Ko, Shuai Guo, Jonathan Hassel, Patricia Celestino-Soper, Ty C Lynnes, James E Tisdale, James J Zheng, Stanley E Taylor, Tatiana Foroud, Michael D Murray, Richard J Kovacs, Xiaochun Li, Shien-Fong Lin, Zhenhui Chen, Matteo Vatta, Peng-Sheng Chen, and Michael Rubart

Am J Physiol Heart Circ Physiol. 2018 Apr 20.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling.

Wilhelm Roell, Alexandra M. Klein, Martin Breitbach, Torsten S. Becker, Ashish Parikh, Jane Lee, Katrin Zimmermann, Shaun Reining, Beth Gabris, Annika Ottersbach, Robert Doran, Britta Engelbrecht, Miriam Schiffer, Kenichi Kimura, Patricia Freitag, Esther Carls, Caroline Geisen, Georg D. Duerr, Philipp Sasse, Armin Welz, Alexander Pfeifer, Guy Salama, Michael Kotlikoff & Bernd K. Fleischmann

Sci Rep. 2018 May 8;8(1):7145.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts.

Gregory S. Hoeker, Mark A. Skarsfeldt, Thomas Jespersen, and Steven Poelzing

Physiol Rep. 2017 Jan;5(1). pii: e13120. doi: 10.14814/phy2.13120. Epub 2017 Jan 13.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure.

Ning Li, Brian J. Hansen, Thomas A. Csepe, Jichao Zhao, Anthony J. Ignozzi, Lidiya V. Sul, Stanislav O. Zakharkin, Anuradha Kalyanasundaram, Jonathan P. Davis, Brandon J. Biesiadecki, Ahmet Kilic, Paul M. L. Janssen, Peter J. Mohler, Raul Weiss, John D. Hummel and Vadim V. Fedorov

Sci Transl Med. 2017 Jul 26;9(400).
SAN preparation
(human)
VSD
(Di]4]ANBDQBS)
MiCAM ULTIMA
(dual or quad camera)
Three-dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural "Fingerprints" of Heart-Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo.

Jichao Zhao, Brian J. Hansen, Yufeng Wang, Thomas A. Csepe, Lidiya V. Sul, Alan Tang, Yiming Yuan, Ning Li, Anna Bratasz, Kimerly A. Powell, Ahmet Kilic, Peter J. Mohler, Paul M. L. Janssen, Raul Weiss, Orlando P. Simonetti, John D. Hummel, and Vadim V. Fedorov

J Am Heart Assoc. 2017 Aug 22;6(8).
Atrial tissue
(human)
VSD
(Di]4]ANBDQBS)
MiCAM ULTIMA
Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation.

Padmini Sirish, Ning Li, Valeriy Timofeyev, Xiao-Dong Zhang, Lianguo Wang, Jun Yang, Kin Sing S. Lee, Ahmed Bettaieb, Sin Mei Ma, Jeong Han Lee, Demetria Su, Victor C. Lau, Richard E. Myers, Deborah K. Lieu, Javier E. López, J. Nilas Young, Ebenezer N. Yamoah, Fawaz Haj, Crystal M. Ripplinger, Bruce D. Hammock, and Nipavan Chiamvimonvat

Circ Arrhythm Electrophysiol. 2016 May; 9(5)
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Anti-arrhythmic effects of interleukin-1 inhibition following myocardial infarction.

Nicole M. De Jesus, Lianguo Wang, Johnny Lai, Robert R. Rigor, Samantha D. Francis Stuart, Donald M. Bers, Merry L. Lindsey, and Crystal M. Ripplinger

Heart Rhythm. 2017 May; 14(5): 727?736.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
β-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia.

Shannon R. Murphy, Lianguo Wang, Zhen Wang, Philip Domondon, Di Lang,1 Beth A. Habecker, Rachel C. Myles, and Crystal M. Ripplinger

Front Physiol. 2017 Aug 28;8:630.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Fluo-5N AM)
MiCAM ULTIMA
(dual camera)
β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle.

C. Kang, A. Badiceanu, J. A. Brennan, C. Gloschat, Y. Qiao, N. A. Trayanova, and I. R. Efimov

Sci Rep. 2017 Nov 21;7(1):15922.
Ventricular wedge preparation
(human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials.

C. Kang, Y. Qiao, G. Li, K. Baechle, P. Camelliti, S. Rentschler, and I. R. Efimov

Sci Rep. 2016; 6: 28798.
Ventricular slice
(human)
VSD
(Di-4-ANEPPS and RH-237)

CaSD
(Rhod-2)
MiCAM ULTIMA
Connexin43 contributes to electrotonic conduction across scar tissue in the intact heart.

Vanessa M. Mahoney, Valeria Mezzano, Gary R. Mirams, Karen Maass, Zhen Li, Marina Cerrone, Carolina Vasquez, Aneesh Bapat, Mario Delmar, and Gregory E. Morley

Sci Rep. 2016 May 31;6:26744. doi: 10.1038/srep26744.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management.

Emile C.A. Nyns, Annemarie Kip, Cindy I. Bart, Jaap J. Plomp; Katja Zeppenfeld, Martin J. Schalij, Antoine A.F. de Vries, Daniël A. Pijnappels

Eur Heart J. 2016 Dec 23. pii: ehw574. doi: 10.1093/eurheartj/ehw574. [Epub ahead of print]
Isolated heart
(rat)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Resolving Myocardial Activation With Novel Omnipolar Electrograms.

Stéphane Massé, Karl Magtibay, Nicholas Jackson, John Asta, Marjan Kusha, Boyang Zhang, Ram Balachandran, Milica Radisic, D. Curtis Deno, and Kumaraswamy Nanthakumar

Circ Arrhythm Electrophysiol. 2016 Jul;9(7):e004107. doi: 10.1161/CIRCEP.116.004107.
Isolated heart
(rabbit)
VSD
(Di-4-ANBDQPQ)
MiCAM ULTIMA
Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.

Elaine Wan, Jeffrey Abrams, Richard L. Weinberg, Alexander N. Katchman, Joseph Bayne, Sergey I. Zakharov, Lin Yang, John P. Morrow, Hasan Garan, and Steven O. Marx

J Clin Invest. 2016 Jan;126(1):112-22. doi: 10.1172/JCI84669. Epub 2015 Nov 23.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.

Elaine Wan, Jeffrey Abrams, Richard L. Weinberg, Alexander N. Katchman, Joseph Bayne, Sergey I. Zakharov, Lin Yang, John P. Morrow, Hasan Garan, and Steven O. Marx

J Clin Invest. 2016 Jan;126(1):112-22. doi: 10.1172/JCI84669. Epub 2015 Nov 23.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Extracellular sodium dependence of the conduction velocity-calcium relationship: evidence of ephaptic self-attenuation.

Sharon A. George, Mohammad Bonakdar, Michael Zeitz, Rafael V. Davalos, James W. Smyth, Steven Poelzing

Am J Physiol Heart Circ Physiol. 2016 May 1;310(9):H1129-39. doi: 10.1152/ajpheart.00857.2015. Epub 2016 Mar 4.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Heart Rate and Extracellular Sodium and Potassium Modulation of Gap Junction Mediated Conduction in Guinea Pigs.

Michael Entz, II, Sharon A. George, Michael J. Zeitz, Tristan Raisch, James W. Smyth, and Steven Poelzing

Front Physiol. 2016 Feb 2;7:16. doi: 10.3389/fphys.2016.00016. eCollection 2016.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart.

Ning Li, Thomas A. Csepe, Brian J. Hansen, Lidiya V. Sul, Anuradha Kalyanasundaram, Stanislav O. Zakharkin, Jichao Zhao, Avirup Guha, David R. Van Wagoner, Ahmet Kilic, Peter J. Mohler, Paul M. L. Janssen, Brandon J. Biesiadecki, John D. Hummel, Raul Weiss and Vadim V. Fedorov

Circulation. 2016 Aug 9;134(6):486-98. doi: 10.1161/CIRCULATIONAHA.115.021165. Epub 2016 Jul 26.
Atria tissue
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
(dual or quad camera)
Spontaneous initiation of premature ventricular complexes and arrhythmias in type 2 long QT syndrome.

Xiaodong Huang, Tae Yun Kim, Gideon Koren, Bum-Rak Choi and Zhilin Qu

Am J Physiol Heart Circ Physiol. 2016 Oct 7:ajpheart.00500.2016. doi: 10.1152/ajpheart.00500.2016. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure.

David S. Park, Akshay Shekhar, Christopher Marra, Xianming Lin, Carolina Vasquez, Sergio Solinas, Kevin Kelley, Gregory Morley, Mitchell Goldfarb, and Glenn I. Fishman

Nat Commun. 2016 Oct 4;7:12966. doi: 10.1038/ncomms12966.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Potassium channels in the Cx43 gap junction perinexus modulate ephaptic coupling: an experimental and modeling study.

Rengasayee Veeraraghavan, Joyce Lin, James P. Keener, Robert Gourdie and Steven Poelzing

Pflugers Arch. 2016 Oct;468(10):1651-61. doi: 10.1007/s00424-016-1861-2. Epub 2016 Aug 11.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
Acute temperature effects on function of the chick embryonic heart.

Vostarek F, Svatunkova J, Sedmera D

Acta Physiol (Oxf). 2016 Aug;217(4):276-86. doi: 10.1111/apha.12691. Epub 2016 May 12.
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)

CaSD
(Rhod-2)
MiCAM ULTIMA
Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension.

Thao P. Nguyen, Ali A. Sovari, Arash Pezhouman, Shankar Iyer, Hong Cao, Christopher Y. Ko, Aneesh Bapat, Nooshin Vahdani, Mostafa Ghanim, Michael C. Fishbein, and Hrayr S. Karagueuzian

J Physiol. 2016 Mar 15;594(6):1689-707. doi: 10.1113/JP271318. Epub 2016 Jan 18.
Isolated heart
(rat)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation.

Arash Pezhouman, Neha Singh, Zhen Song, Michael Nivala, Anahita Eskandari, Hong Cao, Aneesh Bapat, Christopher Y. Ko, Thao Nguyen, Zhilin Qu, Hrayr S. Karagueuzian and James N. Weiss

Circulation. 2015 Oct 20;132(16):1528-37. doi: 10.1161/CIRCULATIONAHA.115.016217. Epub 2015 Aug 12.
Isolated heart
(rabbit)
VSD
(RH-237)
MiCAM ULTIMA
Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130.

Antoinette Olivas, Ryan T. Gardner, Lianguo Wang, Crystal M. Ripplinger, William R. Woodward and Beth A. Habecker

J Neurosci. 2016 Jan 13;36(2):479-88. doi: 10.1523/JNEUROSCI.3556-15.2016.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Deletion of the Serotonin Receptor Type 3A in Mice Leads to Sudden Cardiac Death During Pregnancy.

Hyewon Park, Chang-Myung Oh, Junbeom Park, Hyelim Park, Shanyu Cui, Hyung Suk Kim, Jun Namkung, Sang-kyu Park, Hui-Nam Pak, Moon-Hyoung Lee, Hail Kim, and Boyoung Joung

Circ J. 2015;79(8):1807-15. doi: 10.1253/circj.CJ-14-1074. Epub 2015 May 15.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene.

Sharon A George, Katherine J. Sciuto, Joyce Lin, Mohamed E Salama, James P Keener, Robert G Gourdie, and Steven Poelzing

Pflugers Arch. 2015 Nov;467(11):2287-97. doi: 10.1007/s00424-015-1698-0. Epub 2015 Mar 14.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Human sinoatrial node structure: 3D microanatomy of sinoatrial conduction pathways.

Thomas A. Csepe, Jichao Zhao, Brian J. Hansen, Ning Li, Lidiya V. Sul, Praise Lim, Yufeng Wang, Orlando P. Simonetti, Ahmet Kilic, Peter J. Mohler, Paul M.L. Janssen, Vadim V. Fedorov

Prog Biophys Mol Biol. 2015 Dec 30. pii: S0079-6107(15)00260-6. doi: 10.1016/j.pbiomolbio.2015.12.011. [Epub ahead of print]
SAN tissueVSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Integration of High-Resolution Optical Mapping and 3-Dimensional Micro-Computed Tomographic Imaging to Resolve the Structural Basis of Atrial Conduction in the Human Heart.

Jichao Zhao, Brian J. Hansen, Thomas A. Csepe, Praise Lim, Yufeng Wang, Michelle Williams, Peter J. Mohler, Paul M.L. Janssen, Raul Weiss, John D. Hummel, and Vadim V. Fedorov

Circ Arrhythm Electrophysiol. 2015 Dec;8(6):1514-7. doi: 10.1161/CIRCEP.115.003064.
Isolated atria
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model.

Shuenn]Nan Chiu, Chia]Ti Tsai, Lian]Yu Lin, Shu]Chien Huang, Yih]Sharng Chen, Jou]Kou Wang, Mei]Hwan Wu, Ling]Ping Lai and Jiunn]Lee Lin

J Am Heart Assoc. 2015 Dec 11;4(12). pii: e002173. doi: 10.1161/JAHA.115.002173.
Ventricle wedge preparation
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.

Elaine Wan, Jeffrey Abrams, Richard L. Weinberg, Alexander N. Katchman, Joseph Bayne, Sergey I. Zakharov, Lin Yang, John P. Morrow, Hasan Garan and Steven O. Marx

J Clin Invest. 2016 Jan 4;126(1):112-22. doi: 10.1172/JCI84669. Epub 2015 Nov 23.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart.

Di Lang, Katherine Holzem, Chaoyi Kang, Mengqian Xiao, Hye Jin Hwang, Gregory A. Ewald, Kathryn A. Yamada, and Igor R. Efimov

Circ Arrhythm Electrophysiol. 2015 Apr;8(2):409-19. doi: 10.1161/CIRCEP.114.002065. Epub 2015 Feb 11.
Ventricle wedge preparation
(human)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.

Hengtao Zhang, Albert Y. Sun, Jong J. Kim, Victoria Graham, Elizabeth A. Finch, Igor Nepliouev, Guiling Zhao, Tianyu Li, W. J. Lederer, Jonathan A. Stiber, Geoffrey S. Pitt, Nenad Bursac and Paul B. Rosenberg

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5618-27. doi: 10.1073/pnas.1503847112. Epub 2015 Sep 30.
SAN tissueCaSD
(Rhod-2 AM)
MiCAM ULTIMA
Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload.

Katherine M. Holzem, Joseph T. Marmerstein, Eli J. Madden and Igor R. Efimov

Physiol Rep. 2015 Aug;3(8). pii: e12489. doi: 10.14814/phy2.12489.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.

Brian J. Hansen, Jichao Zhao, Thomas A. Csepe, Brandon T. Moore, Ning Li, Laura A. Jayne, Anuradha Kalyanasundaram, Praise Lim, Anna Bratasz, Kimerly A. Powell, Orlando P. Simonetti, Robert S.D. Higgins, Ahmet Kilic, Peter J. Mohler, Paul M.L. Janssen, Raul Weiss, John D. Hummel and Vadim V. Fedorov

Eur Heart J. 2015 Jun 8. pii: ehv233. [Epub ahead of print].
Isolated heart
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
(dual camera)
Burst pacemaker activity of the sinoatrial node in sodium-calcium exchanger knockout mice.

Angelo G. Torrente, Rui Zhang, Audrey Zaini, Jorge F. Giani, Jeanney Kang, Scott T. Lamp, Kenneth D. Philipson and Joshua I. Goldhaber

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9769-74. doi: 10.1073/pnas.1505670112. Epub 2015 Jul 20.
SAN/atria tissueVSD
(RH-237)
MiCAM ULTIMA
Engineered heart slices for electrophysiological and contractile studies.

Adriana Blazeski, Geran M. Kostecki and Leslie Tung

Biomaterials. 2015 Jul;55:119-28. doi: 10.1016/j.biomaterials.2015.03.026. Epub 2015 Apr 17.
Heart sliceVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model.

Milan Gautam, Daiki Fujita, Kazuhiro Kimura, Hinako Ichikawa, Atsushi Izawa, Masamichi Hirose, Toshihide Kashihara, Mitsuhiko Yamada, Masafumi Takahashi, Uichi Ikeda and Yuji Shiba

J Mol Cell Cardiol. 2015 Apr;81:139-49. doi: 10.1016/j.yjmcc.2015.02.012. Epub 2015 Feb 24.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM02
Quantification of the Transmural Dynamics of Atrial Fibrillation by Simultaneous Endocardial and Epicardial Optical Mapping in an Acute Sheep Model.

Sarah R. Gutbrod, Richard Walton, Stephen Gilbert, Valentin Meillet, Pierre Jaïs, Mélèze Hocini, Michel Haïssaguerre, Rémi Dubois, Olivier Bernus and Igor Efimov

Circ Arrhythm Electrophysiol. 2015 Feb 24. pii: CIRCEP.114.002545. [Epub ahead of print]
Isolated atria
(sheep)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
(dual camera)
Targeting protein tyrosine phosphatase σ after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias.

R. T. Gardner, L. Wang, B. T. Lang, J. M. Cregg, C. L. Dunbar, W. R. Woodward, J. Silver, C. M. Ripplinger and B. A. Habecker

Nat Commun. 2015 Feb 2;6:6235. doi: 10.1038/ncomms7235.
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study.

Rengasayee Veeraraghavan, Joyce Lin, Gregory S. Hoeker, James P. Keener, Robert G. Gourdie and Steven Poelzing

Pflugers Arch. 2015 Jan 13. [Epub ahead of print]
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
Atherosclerosis exacerbates arrhythmia following myocardial infarction: Role of myocardial inflammation.

Nicole M. De Jesus, Lianguo Wang, Anthony W. Herren, Jingjing Wang, Fatemah Shenasa, Donald M. Bers, Merry L. Lindsey and Crystal M. Ripplinger

Heart Rhythm. 2015 Jan;12(1):169-78. doi: 10.1016/j.hrthm.2014.10.007. Epub 2014 Oct 7.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optical Mapping of Intra-Sarcoplasmic Reticulum Ca2+ and Transmembrane Potential in the Langendorff-perfused Rabbit Heart.

Lianguo Wang, Nicole M. De Jesus, and Crystal M. Ripplinger

J Vis Exp. 2015 Sep 10;(103)
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Fluo-5N AM)
MiCAM ULTIMA
(dual camera)
Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias.

Qing Lou, Andriy E. Belevych, Przemysław B. Radwański, Bin Liu, Anuradha Kalyanasundaram, Bjorn C. Knollmann, Vadim V. Fedorov and Sándor Györke

J Physiol. 2014 Nov 10. [Epub ahead of print]
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Pacing-Induced Non-Uniform Ca2+ Dynamics in Rat Atria Revealed by Rapid-Scanning Confocal Microscopy.

Yan Jiang, Hideo Tanaka, Taka-aki Matsuyama, Yoshihisa Yamaoka and Tetsuro Takamatsu

Acta Histochem Cytochem. May 1, 2014; 47(2): 59-65. Published online Apr 25, 2014. doi: 10.1267/ahc.14014
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM02
Ca2+/calmodulin-dependent protein kinase II increases the susceptibility to the arrhythmogenic action potential alternans in spontaneously hypertensive rats.

Hirofumi Mitsuyama, Hisashi Yokoshiki, Masaya Watanabe, Kazuya Mizukami, Junichi Shimokawa and Hiroyuki Tsutsui

Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H199-206. doi: 10.1152/ajpheart.00387.2012. Epub 2014 May 23.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM02
Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation.

Lianguo Wang, Rachel C. Myles, Nicole M. De Jesus, Alex K.P. Ohlendorf, Donald M. Bers and Crystal M. Ripplinger

Circ Res. 2014 Apr 25;114(9):1410-21. doi: 10.1161/CIRCRESAHA.114.302505. Epub 2014 Feb 25.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Fluo-5N AM)
MiCAM ULTIMA
(dual camera)
Decreased IK1 and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart.

Rachel C. Myles, Lianguo Wang, Donald M. Bers and Crystal M. Ripplinger

J Physiol. 2014 Sep 5. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Mitochondrial depolarization and electrophysiological changes during ischemia in the rabbit and human heart.

Matthew S Sulkin, Bastiaan J Boukens, Megan Tetlow, Sarah R Gutbrod, Fu Siong Ng and Igor R. Efimov
Am J Physiol Heart Circ Physiol. 2014 Aug 15. pii: ajpheart.00437.2014. [Epub ahead of print]
Isolated heart
(mouse)
VSD
(RH-237 and TMRM)
MiCAM ULTIMA
(dual camera)
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.

Qing Lou, Brian J. Hansen, Olga Fedorenko, Thomas A. Csepe, Anuradha Kalyanasundaram, Ning Li, Lori T. Hage, Alexey V. Glukhov, George E. Billman, Raul Weiss, Peter J. Mohler, Sándor Györke, Brandon J. Biesiadecki, Cynthia A. Carnes, PharmD and Vadim V. Fedorov

Circulation. 2014 Jul 22;130(4):315-24. doi: 10.1161/CIRCULATIONAHA.113.007086. Epub 2014 May 16.
Isolated heart
(dog)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
(dual camera)
3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium.

Lizhi Xu, Sarah R. Gutbrod, Andrew P. Bonifas, Yewang Su, Matthew S. Sulkin, Nanshu Lu, Hyun-Joong Chung, Kyung-In Jang, Zhuangjian Liu, Ming Ying, Chi Lu, R. Chad Webb, Jong-Seon Kim, Jacob I. Laughner, Huanyu Cheng, Yuhao Liu, Abid Ameen, Jae-Woong Jeong, Gwang-Tae Kim, Yonggang Huang, Igor R. Efimov and John A. Rogers

Nat Commun. 2014 Feb 25;5:3329. doi: 10.1038/ncomms4329.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS or RH-237)
MiCAM ULTIMA
c-Src Kinase Inhibition Reduces Arrhythmia Inducibility and Connexin43 Dysregulation After Myocardial Infarction.

Cody A. Rutledge, Fu Siong Ng, Matthew S. Sulkin, Ian D. Greener, Artem M. Sergeyenko, Hong Liu, Joanna Gemel, Eric C. Beyer, Ali A. Sovari, Igor R. Efimov and Samuel C. Dudley

J Am Coll Cardiol. 2014 Mar 11;63(9):928-34. doi: 10.1016/j.jacc.2013.10.081. Epub 2014 Jan 8.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts.

Arash Pezhouman, Sepideh Madahian, Hayk Stepanyan, Hayk Ghukasyan, Zhilin Qu, Luiz Belardinelli and Hrayr S. Karagueuzian

Heart Rhythm. 2014 Mar;11(3):492-501. doi: 10.1016/j.hrthm.2013.11.026. Epub 2013 Nov 28.
Isolated heart
(rat)
VSD
(RH-237)
MiCAM ULTIMA
Transmural ultrasound imaging of thermal lesion and action potential changes in perfused canine cardiac wedge preparations by high intensity focused ultrasound ablation.

Ziqi Wu, Madhu S. R. Gudur and Cheri X. Deng

PLoS One. 2013 Dec 12;8(12):e82689. doi: 10.1371/journal.pone.0082689. eCollection 2013.
Isolated heart
(dog)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

Angel J. de la Rosa, Jorge N. Domínguez, David Sedmera, Bara Sankova, Leif Hove-Madsen, Diego Franco and Amelia E. Aránega

Cardiovasc Res. 2013 Jun 1;98(3):504-14. doi: 10.1093/cvr/cvt076. Epub 2013 Mar 29.
Isolated heart
(mouse embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation.

Jeffrey R. Erickson, Laetitia Pereira, Lianguo Wang, Guanghui Han, Amanda Ferguson, Khanha Dao, Ronald J. Copeland, Florin Despa, Gerald W. Hart, Crystal M. Ripplinger and Donald M. Bers

Nature. 2013 Oct 17;502(7471):372-6. doi: 10.1038/nature12537. Epub 2013 Sep 29.
Isolated heart
(rat)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Multi-Stage Electrotherapy Delivered Through Chronically Implanted Leads Terminates Atrial Fibrillation with Lower Energy than a Single Biphasic Shock.

Ajit H. Janardhan, Sarah R. Gutbrod, Wenwen Li, Di Lang, Richard B. Schuessler and Igor R. Efimov

J Am Coll Cardiol. 2013 Sep 26. pii: S0735-1097(13)05356-4. doi: 10.1016/j.jacc.2013.07.098. [Epub ahead of print]
Isolated heart
(dog)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Sinoatrial node reentry in a canine chronic left ventricular infarct model: role of intranodal fibrosis and heterogeneity of refractoriness.

Alexey V. Glukhov, Lori T. Hage, Brian J. Hansen, Adriana Pedraza-Toscano, Pedro Vargas-Pinto, Robert L. Hamlin, Raul Weiss, Cynthia A. Carnes, George E. Billman and Vadim V. Fedorov

Circ Arrhythm Electrophysiol. 2013 Oct 1;6(5):984-94. doi: 10.1161/CIRCEP.113.000404. Epub 2013 Aug 19.
Isolated heart
(dog)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1.

Dolkun Rahmutula, Gregory M. Marcus, Emily E. Wilson, Chun-Hua Ding, Yuanyuan Xiao, Agnes C. Paquet, Rebecca Barbeau, Andrea J. Barczak, David J. Erle and Jeffrey E. Olgin

Cardiovasc Res. 2013 Sep 1;99(4):769-79. doi: 10.1093/cvr/cvt074. Epub 2013 Apr 23.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Functional roles of KATP channel subunits in metabolic inhibition.

Alexey V. Glukhova, Keita Uchida, Igor R. Efimov, Colin G. Nichols

J Mol Cell Cardiol. 2013 Apr 23;62C:90-98. doi: 10.1016/j.yjmcc.2013.04.016. [Epub ahead of print]
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Mesenchymal Stem Cell Transplantation Mitigates Electrophysiological Remodeling in a Rat Model of Myocardial Infarction.

Patrick F.H. Lai, Brian K. Panama, Stéphane Mass&#233, Guangming Li, Yaoguang Zhang, Marjan Kusha, Talha A. Farid, John Asta, Peter H. Backx, Terrence M. Yau and Kumaraswamy Nanthakumar

J Cardiovasc Electrophysiol. 2013 Apr 8. doi: 10.1111/jce.12162. [Epub ahead of print]
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
(dual camera)
Calcium measurements from whole heart using Rhod-2.

Bum-Rak Choi

Methods Mol Biol. 2013;937:217-28.
Isolated heart
(rabbit, guinea pig, mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium.

Grazia Ammirabile, Alessandra Tessari, Viviana Pignataro, Dorota Szumska, Fabio Sutera Sardo, Jiri Benes, Jr, Mariangela Balistreri, Shoumo Bhattacharya, David Sedmera and Marina Campione

Cardiovasc Res. 2012 Feb 1;93(2):291-301. doi: 10.1093/cvr/cvr314. Epub 2011 Nov 23.
Isolated heart
(mouse embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
The effect of connexin40 deficiency on ventricular conduction system function during development.

Barbora Sankova, Jiri Benes Jr, Eliska Krejci, Laurent Dupays, Magali Theveniau-Ruissy, Lucile Miquerol and David Sedmera

Cardiovasc Res. 2012 Sep 1;95(4):469-79. doi: 10.1093/cvr/cvs210. Epub 2012 Jun 27.
Isolated heart
(embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Identification and Functional Characterization of Cardiac Pacemaker Cells in Zebrafish.

Federico Tessadori, Jan Hendrik van Weerd, Silja B. Burkhard, Arie O. Verkerk, Emma de Pater, Bastiaan J. Boukens, Aryan Vink, Vincent M. Christoffels and Jeroen Bakkers

PLoS One. 2012;7(10):e47644. doi: 10.1371/journal.pone.0047644. Epub 2012 Oct 16.
Isolated heart
(zebrafish)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes.

Jacob I Laughner, Fu Siong Ng, Matthew S Sulkin, R Martin Arthur and Igor R Efimov

Am J Physiol Heart Circ Physiol. 2012 Oct;303(7):H753-65. doi: 10.1152/ajpheart.00404.2012. Epub 2012 Jul 20.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Focal but reversible diastolic sheet dysfunction reflects regional calcium mishandling in dystrophic mdx mouse hearts.

Ya-Jian Cheng, Di Lang, Shelton D Caruthers, Igor R Efimov, Junjie Chen and Samuel A Wickline

Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H559-68. doi: 10.1152/ajpheart.00321.2012. Epub 2012 Jul 9.
Isolated heart
(mouse)
CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Oscillation in Cycle Length Induces Transient Discordant and Steady-State Concordant Alternans in the Heart.

Seth H. Weinberg and Leslie Tung

PLoS One. 2012;7(7):e40477. Epub 2012 Jul 5.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Construction of 3D MR image-based computer models of pathologic hearts, augmented with histology and optical fluorescence imaging to characterize action potential propagation.

Mihaela Pop, Maxime Sermesant, Garry Liu, Jatin Relan, Tommaso Mansi, Alan Soong, Jean-Marc Peyrat, Michael V. Truong, Paul Fefer, Elliot R. McVeigh, Herve Delingette, Alexander J. Dick, Nicholas Ayache, Graham A. Wright

Med Image Anal. 2012 Feb;16(2):505-23. Epub 2011 Dec 6.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Conduction and refractory disorders in the diabetic atrium.

Masaya Watanabe, Hisashi Yokoshiki, Hirofumi Mitsuyama, Kazuya Mizukami, Taisuke Ono, and Hiroyuki Tsutsui

Am J Physiol Heart Circ Physiol. 2012 Jul;303(1):H86-95. Epub 2012 May 4.
Isolated heart
(rat)
VSD
(Di-4-ANEPPS)
MiCAM02
Local β-Adrenergic Stimulation Overcomes Source-Sink Mismatch to Generate Focal Arrhythmia.

Rachel C. Myles, Lianguo Wang, Chaoyi Kang, Donald M. Bers and Crystal M. Ripplinger

Circ Res. 2012 May 25;110(11):1454-64. Epub 2012 Apr 26.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias.

Aneesh Bapat, Thao P. Nguyen, Jong-Hwan Lee Ali A. Sovari, Michael C. Fishbein, James N. Weiss and Hrayr S. Karagueuzian

Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2331-40. Epub 2012 Mar 30.
Isolated heart
(rat)
VSD
(RH-237)
MiCAM ULTIMA
A Novel, Minimally Invasive, Segmental Myocardial Infarction with a Clear Healed Infarct Borderzone in Rabbits.

Ohad Ziv, Lorraine Schofield, Emily Lau, Leonard Chaves, Dyviang Patel, Paul Jeng, Xuwen Peng, Bum-Rak Choi and Gideon Koren

Am J Physiol Heart Circ Physiol. 2012 Mar 23. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Conduction remodeling in human end-stage nonischemic left ventricular cardiomyopathy.

Alexey V. Glukhov, Vadim V. Fedorov, Paul W. Kalish, Vinod K. Ravikumar, Qing Lou, Deborah Janks, Richard B. Schuessler, Nader Moazami and Igor R. Efimov

Circulation. 2012 Apr 17;125(15):1835-47. Epub 2012 Mar 12.
Isolated heart
(dog and human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Three Potential Mechanisms for Failure of HIFU Ablation in Cardiac Tissue.

Jacob I. Laughner, Matthew S. Sulkin, Ziqi Wu, Cheri X. Deng and Igor R. Efimov

Circ Arrhythm Electrophysiol. 2012 Feb 9. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Inter-model consistency and complementarity: Learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology.

O. Camara, M. Sermesant, P. Lamata, L. Wang,M. Pop, J. Relan, M. De Craene, H. Delingette, H. Liu, S. Niederer, A. Pashaei, G. Plank, D. Romero R. Sebastian, K.C.L. Wong, H. Zhang, N. Ayache, A.F. Frangi, P. Shi, N.P. Smith G.A. Wright

Prog Biophys Mol Biol. 2011 Oct;107(1):122-33. Epub 2011 Jul 20.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice.

Paulus Kirchhof, Eloi Marijond, Larissa Fabritza, Na Li, Wei Wang, Tiannan Wang, Kirsten Schulte, Juliane Hanstein, Jan S. Schulte, Mathis Vogel, Nathalie Mougenot, Sandra Laakmann, Lisa Fortmueller, Jens Eckstein, Sander Verheule, Sven Kaese, Ariane Staab, Stephanie Grote-Wessels, Ulrich Schotten, Ghassan Moubarak, Xander H.T. Wehrens, Wilhelm Schmitz, Stéphane Hatem, Frank Ulrich Müller.

Int J Cardiol. 2011 Nov 15. [Epub ahead of print]
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.

Stacey Rentschler, Brett S. Harris, Laura Kuznekoff, Rajan Jain, Lauren Manderfield, Min Min Lu, Gregory E. Morley, Vickas V. Patel and Jonathan A. Epstein

J Clin Invest. 2011 Feb;121(2):525-33. doi: 10.1172/JCI44470. Epub 2011 Jan 25.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Transmural Heterogeneity and Remodeling of Ventricular Excitation-Contraction Coupling in Human Heart Failure.

Qing Lou, Vadim V. Fedorov, Alexey V. Glukhov, Nader Moazami, Vladimir G. Fast and Igor R. Efimov

Circulation. 2011 May 3;123(17):1881-90. Epub 2011 Apr 18.
Isolated heart
(human)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Spatiotemporal control of heart rate in a rabbit heart.

Di Lang, Valentin Petrov, Qing Lou, Grigory Osipov and Igor R. Efimov

J Electrocardiol. 2011 Nov-Dec;44(6):626-34. Epub 2011 Sep 19.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias.

Benjamin F. Remo, Jiaxiang Qu, Frank M. Volpicelli, Steven Giovannone, Daniel Shin, Joshua Lader, Fang-yu Liu, Jie Zhang, Danielle S. Lent, Gregory E. Morley and Glenn I. Fishman

Circ Res. 2011 Jun 10;108(12):1459-66. Epub 2011 Apr 28.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts.

Vadim V. Fedorov, Christina M. Ambrosi, Geran Kostecki, William J. Hucker, Alexey V. Glukhov, Joseph P. Wuskell, Leslie M. Loew, Nader Moazami and Igor R. Efimov

Circ Arrhythm Electrophysiol. 2011 Aug 1;4(4):515-25. Epub 2011 Jun 6.
Isolated heart
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
(dual camera)
Role of Pyk2 in cardiac arrhythmogenesis.

Di Lang, Alexey V. Glukhov, Tatiana Efimova and Igor R. Efimov

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H975-83. Epub 2011 Jun 10.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Spatiotemporal electrophysiological changes in a murine ablation model.

Scott A. Bernstein, Srikant Duggirala, Michael Floberg, Pehr Elfvendal, Laura M. Kuznekoff, Joshua M. Lader, Carolina Vasquez and Gregory E. Morley

Europace. 2011 Oct;13(10):1494-500. Epub 2011 Jun 28.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
In-vitro recording of adult zebrafish heart electrocardiogram - a platform for pharmacological testing.

Chia-Ti Tsai, Cho-Kai Wu, Fu-Tien Chiang, Chuen-Den Tseng, Jen-Kuang Lee, Chih-Chieh Yu, Yi-Chih Wang, Ling-Ping Lai, Jiunn-Lee Lin and Juey-Jen Hwang

Clin Chim Acta. 2011 Oct 9;412(21-22):1963-7. Epub 2011 Jul 8.
Isolated heart
(zebrafish)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Remodeling of atrial ATP-sensitive K+ channels in a model of salt-induced elevated blood pressure.

Joshua M. Lader, Carolina Vasquez, Li Bao, Karen Maass, Jiaxiang Qu, Eirini Kefalogianni, Glenn I. Fishman, William A. Coetzee and Gregory E. Morley

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H964-74. Epub 2011 Jul 1.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.

Vadim V. Fedorov, Alexey V. Glukhov, Christina M. Ambrosi, Geran Kostecki, Roger Chang, Deborah Janks, Richard B. Schuessler, Nader Moazami, Colin G. Nichols and Igor R. Efimov

J Mol Cell Cardiol. 2011 Aug;51(2):215-25. Epub 2011 May 7.
Isolated heart
(human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
(dual camera)
Multiparametric Optical Mapping of the Langendorff-perfused Rabbit Heart (Video Article).

Qing Lou, Wenwen Li and Igor R. Efimov

J. Vis. Exp. (55), e3160, DOI: 10.3791/3160 (2011)
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Optical Mapping of Action Potentials and Calcium Transients in the Mouse Heart (Video Article).

Di Lang, Matthew Sulkin, Qing Lou and Igor R. Efimov

J. Vis. Exp. (55), e3275, DOI: 10.3791/3275 (2011)
Isolated heart
(mouse)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles.

Su-Kiat Chua, Po-Cheng Chang, Mitsunori Maruyama, Isik Turker, Tetsuji Shinohara, Mark J. Shen, Zhenhui Chen, Changyu Shen, Michael Rubart-von der Lohe, John C. Lopshire, Masahiro Ogawa, James N. Weiss, Shien-Fong Lin, Tomohiko Ai and Peng-Sheng Chen

Circ Res. 2011 Apr 15;108(8):971-9. Epub 2011 Feb 24.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice.

Mitsunori Maruyama, Bai-Yan Li, Hanying Chen, Xuehong Xu, Long-Sheng Song, Silvia Guatimosim, Wuqiang Zhu, Weidong Yong, Wenjun Zhang, Guixue Bu, Shien-Fong Lin, Michael C. Fishbein, W. Jonathan Lederer, John H. Schild, Loren J. Field, Michael Rubart, Peng-Sheng Chen and Weinian Shou

Circ Res. 2011 Apr 29;108(9):1042-52. Epub 2011 Mar 3.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
(dual camera)
Intracellular calcium and the mechanism of anodal supernormal excitability in langendorff perfused rabbit ventricles.

Boyoung Joung, Hyung-Wook Park, Mitsunori Maruyama, Liang Tang, Juan Song, Seongwook Han, Gianfranco Piccirillo, James N. Weiss, Shien-Fong Lin and Peng-Sheng Chen

Circ J. 2011 Apr;75(4):834-43. Epub 2011 Feb 2.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Delayed afterdepolarization in intact canine sinoatrial node as a novel mechanism for atrial arrhythmia.

Boyoung Joung, Hong Zhang, Tetsuji Shinohara, Mitsunori Maruyama, Seongwook Han, Daehyeok Kim, Eue-Keun Choi, Young-Keun On, Shien-Fong Lin and Peng-Sheng Chen

J Cardiovasc Electrophysiol. 2011 Apr;22(4):448-54. doi: 10.1111/j.1540-8167.2010.01905.x. Epub 2010 Oct 6.
Isolated heart
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome.

Mitsunori Maruyama, Shien-Fong Lin, Yuanfang Xie, Su-Kiat Chua, Boyoung Joung, Seongwook Han, Tetsuji Shinohara, Mark J. Shen, Zhilin Qu, James N. Weiss and Peng-Sheng Chen

Circ Arrhythm Electrophysiol. 2011 Feb;4(1):103-11. Epub 2010 Nov 15.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Personalisation of a Cardiac Electrophysiology Model using Optical Mapping and MRI for Prediction of Changes with Pacing.

Jatin Relan, Mihaela Pop, H Delingette, G Wright, N Ayache and M Sermesant

IEEE Trans Biomed Eng. 2011 Jan 20. [Epub ahead of print]
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
The role of the calcium and the voltage clocks in sinoatrial node dysfunction.

Boyoung Joung, Peng-Sheng Chen and Shien-Fong Lin

Yonsei Med J. 2011 Mar 1;52(2):211-9.
Isolated heart
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Assessment of cardiac conduction: basic principles of optical mapping.

Chunhua Ding and Thomas H. Everett

Methods Mol Biol. 2010;660:239-52.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS or PGH-I)
MiCAM02
PITX2c is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression.

Paulus Kirchhof, Peter C. Kahr, Sven Kaese, Ilaria Piccini, Ismail Vokshi, Hans-Heinrich Scheld, Heinrich Rotering, Lisa Fortmueller, Sandra Laakmann, Sander Verheule, Ulrich Schotten, Larissa Fabritz and Nigel A. Brown

Circ Cardiovasc Genet. 2011 Apr;4(2):123-33. Epub 2011 Jan 31.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Alternans of diastolic intracellular calcium elevation as the mechanism of bidirectional ventricular tachycardia in a rabbit model of Andersen-Tawil syndrome.

Mitsunori Maruyama, Shien-Fong Lin and Peng-Sheng Chen

Heart Rhythm. 2010 Dec 15. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Ca2+ clock malfunction in a canine model of pacing-induced heart failure.

Tetsuji Shinohara, Hyung-Wook Park, Seongwook Han, Mark J. Shen, Mitsunori Maruyama, Daehyeok Kim, Peng-Sheng Chen and Shien-Fong Lin

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1805-11. Epub 2010 Oct 1.
Isolated heart
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Calcium dynamics and the mechanisms of atrioventricular junctional rhythm.

Daehyeok Kim, Tetsuji Shinohara, Boyoung Joung, Mitsunori Maruyama, Eue-Keun Choi, Young Keun On, Seongwook Han, Michael C. Fishbein, Shien-Fong Lin and Peng-Sheng Chen

J Am Coll Cardiol. 2010 Aug 31;56(10):805-12.
Isolated heart
(mongrel dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Tachybradycardia in the isolated canine right atrium induced by chronic sympathetic stimulation and pacemaker current inhibition.

Boyoung Joung, Tetsuji Shinohara, Hong Zhang, Daehyeok Kim, Eue-Keun Choi, Yong-Keun On, Gianfranco Piccirillo, Peng-Sheng Chen and Shien-Fong Lin

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H634-42. Epub 2010 Jul 2.
Isolated heart
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Cytosolic calcium accumulation and delayed repolarization associated with ventricular arrhythmias in a guinea pig model of Andersen-Tawil syndrome.

Przemysław B. Radwański, Rengasayee Veeraraghavan and Steven Poelzing

Heart Rhythm. 2010 Oct;7(10):1428-1435.e1. Epub 2010 Apr 7.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)

CaSD
(Indo-1)
MiCAM02
(dual camera)
Anatomy and electrophysiology of the human AV node.

Thomas Kurian, Christina Ambrosi, William Hucker, Vadim V. Fedorov and Igor R. Efimov

Pacing Clin Electrophysiol. 2010 Jun 1;33(6):754-62. Epub 2010 Feb 18.
Isolated heart
(human)
VSDMiCAM ULTIMA
In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies.

Lior Gepstein, Chunhua Ding, Dolkun Rehemedula, Emily E. Wilson, Lior Yankelson, Oren Caspi, Amira Gepstein, Irit Huber and Jeffery E. Olgin

Stem Cells. 2010 Dec;28(12):2151-61.
Isolated heart
(rat)
VSD
(PGH I)
MiCAM02
(dual camera)
Termination of sustained atrial flutter and fibrillation using low-voltage multiple-shock therapy.

Christina M. Ambrosi, Crystal M. Ripplinger, Igor R. Efimov and Vadim V. Fedorov

Heart Rhythm. 2011 Jan;8(1):109-10.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optical mapping of the isolated coronary-perfused human sinus node.

Vadim V. Fedorov, Alexey V. Glukhov, Roger Chang, Geran Kostecki, Hyuliya Aferol, William J. Hucker, Joe Wuskell, Leslie M. Loew, Richard B. Schuessler, Nader Moazami and Igor R. Efimov

J Am Coll Cardiol. 2010 Oct 19;56(17):1386-94.
Isolated heart
(human)
VSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
ST segment elevation by current-to-load mismatch: an experimental and computational study.

Mark G. Hoogendijk, Mark Potse, Alain Vinet, Jacques M.T. de Bakker and Ruben Coronel

Heart Rhythm. 2011 Jan;8(1):111-8. Epub 2010 Oct 30.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability.

Andreas Blana, Sven Kaese, Lisa Fortmüller, Sandra Laakmann, Dierk Damke, Kelly van Bragt, Jens Eckstein, Ilaria Piccini, Uwe Kirchhefer, Stanley Nattel, Günter Breithardt, Peter Carmeliet, Edward Carmeliet, Ulrich Schotten, Sander Verheule, Paulus Kirchhof and Larissa Fabritz

Heart Rhythm. 2010 Dec;7(12):1862-9. Epub 2010 Aug 19.
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Complex interactions between the sinoatrial node and atrium during reentrant arrhythmias in the canine heart.

Vadim V. Fedorov, Roger Chang, Alexey V. Glukhov, Geran Kostecki, Deborah Janks, Richard B. Schuessler and Igor R. Efimov

Circulation. 2010 Aug 24;122(8):782-9. Epub 2010 Aug 9.
Isolated heart
(mongrel dog)
VSD
(Di-4-ANEPPS or RH-237)
MiCAM ULTIMA
Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice.

Alexey V. Glukhov, Vadim V. Fedorov, Mark E. Anderson, Peter J. Mohler and Igor R. Efimov

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H482-91. Epub 2010 Jun 4.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Differential K(ATP) channel pharmacology in intact mouse heart.

Alexey V. Glukhov, Thomas P. Flagg, Vadim V. Fedorov, Igor R. Efimov and Colin G. Nichols

J Mol Cell Cardiol. 2010 Jan;48(1):152-60. Epub 2009 Sep 8.
Isolated heart
(mouse)
VSD
(RH-237)
MiCAM ULTIMA
Electrophysiological Studies of Transgenic Long QT Type 1 and 2 Rabbits Reveal Genotype-Specific Differences in Ventricular Refractoriness and His Conduction.

Katja E. Odening, Malcolm Kirk, Michael Brunner, Ohad Ziv, Peem Lorvidhaya, Gong Xin Liu, Lorraine Schofield, Leonard Chaves, Xuwen Peng, Manfred Zehender, Bum-Rak Choi and Gideon Koren

Am J Physiol Heart Circ Physiol. 2010 Jun 25. [Epub ahead of print]
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Transmural dispersion of repolarization in failing and nonfailing human ventricle.

Alexey V. Glukhov, Vadim V. Fedorov, Qing Lou, Vinod K. Ravikumar, Paul W. Kalish, Richard B. Schuessler, Nader Moazami and Igor R. Efimov

Circ Res. 2010 Mar 19;106(5):981-91. Epub 2010 Jan 21.
Isolated heart
(human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Electrical Activation of Sinus Venosus Myocardium and Expression Patterns of RhoA and Isl-1 in the Chick Embryo.

Rebecca Vicente-Steijn, Denise P. Kolditz, Edris A.F. Mahtab, Saïd F.A. Askar, Noortje A.M. Bax, Linda M. Van Der Graaf, Lambertus J. Wisse, Robert Passier, Daniël A. Pijnappels, Martin J. Schalij, Robert E. Poelmann, Adriana C. Gittenberger-De Groot and Monique R.M. Jongbloed

J Cardiovasc Electrophysiol. 2010 Apr 29. [Epub ahead of print]
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Pharmacological Activation of IKr Impairs Conduction in Guinea Pig Hearts.

Anders Peter Larsen, Søren-Peter Olesen, Morten Grunnet and Steven Poelzing

J Cardiovasc Electrophysiol. Published Online: Feb 16 2010
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
High-resolution optical mapping of ventricular tachycardia in rats with chronic myocardial infarction.

Chunhua Ding, Lior Gepstein, Duy Thai Nguyen, Emily Wilson, George Hulley, Andrew Beaser, Randall J. Lee and Jeffrey Olgin

Pacing Clin Electrophysiol. 2010 Jun 1;33(6):687-95.
Isolated heart
(rat)
VSD
(PGH I)
MiCAM02
Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias.

Duy T. Nguyen, Chunhua Ding, Emily Wilson, Gregory M. Marcus and Jeffrey E. Olgin

Heart Rhythm. 2010 Apr 27.
Isolated heart
(rat)
VSD
MiCAM ULTIMA
Effects of mechanical loading on early conduction system differentiation in the chick.

Barbora Sankova, Jakub Machalek and David Sedmera

Am J Physiol Heart Circ Physiol. 2010 May;298(5):H1571-6.
Isolated heart
(chick embryo)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Mapping cardiac pacemaker circuits: methodological puzzles of the sinoatrial node optical mapping.

Igor R. Efimov, Vadim V. Fedorov, Boyoung Joung and Shien-Fong Lin

Circ Res. 2010 Feb 5;106(2):255-71.
Isolated heart
(rabbit, dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Transmural Dispersion of Repolarization in Failing and Nonfailing Human Ventricle.

Alexey V. Glukhov, Vadim V. Fedorov, Qing Lou, Vinod K. Ravikumar, Paul W. Kalish, Richard B. Schuessler, Nader Moazami and Igor R. Efimov

Circ Res.2010; 0:
Isolated heart
(human)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Induction of atrial ectopic beats with calcium release inhibition: Local hierarchy of automaticity in the right atrium.

Tetsuji Shinohara, Boyoung Joung, Daehyeok Kim, Mitsunori Maruyama, Hsiang-Ning Luk, Peng-Sheng Chen and Shien-Fong Lin

Heart Rhythm. 2010 Jan;7(1):110-116
Isolated heart
(mongrel dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Origin of complex behaviour of spatially discordant alternans in a transgenic rabbit model of type 2 long QT syndrome.

Ohad Ziv, Eduardo Morales, Yoon-kyu Song, Xuwen Peng, Katja E Odening, Alfred E Buxton, Alain Karma, Gideon Koren and Bum-Rak Choi

J Physiol. 2009 Oct 1;587(Pt 19):4661-80.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Diastolic Intracellular Calcium-Membrane Voltage Coupling Gain and Postshock Arrhythmias. Role of Purkinje Fibers and Triggered Activity.

Mitsunori Maruyama, Boyoung Joung, Liang Tang, Tetsuji Shinohara, Young-Keun On, Seongwook Han, Eue-Keun Choi, Dae-Hyeok Kim, Mark J. Shen, James N. Weiss, Shien-Fong Lin and Peng-Sheng Chen

Circ Res. 2010 Feb 5;106(2):399-408. Epub 2009 Nov 19.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Optical mapping of VF in isolated swine hearts with scars.

Mihaela Pop, Alan Soong, John M. Hudson, Paul Fefer, Alexander Dick and Graham A. Wright

Biophysical Journal, Volume 96, Issue 3, Pages 262a-262a
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
Mechanisms of sinoatrial node dysfunction in a canine model of pacing-induced atrial fibrillation.

Boyoung Joung, Shien-Fong Lin, Zhenhui Chen, Patrick S. Antoun, Mitsunori Maruyama, Seongwook Han, Gianfranco Piccirillo, Marcelle Stucky, Douglas P. Zipes, FHRS, Peng-Sheng Chen and Mithilesh Kumar Das>

Heart Rhythm. 2010 Jan;7(1):88-95. Epub 2009 Sep 16.
Isolated heart
(dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart.

Jiaxiang Qu, Frank M. Volpicelli, Luis I. Garcia, Nefthi Sandeep, Jie Zhang, Lucrecia Márquez-Rosado, Paul D. Lampe and Glenn I. Fishman

Circ Res. 2009 Feb 13;104(3):365-71.

Isolated heart
(mouse)
VSD
MiCAM ULTIMA
Simultaneous optical mapping of intracellular free calcium and action potentials from Langendorff perfused hearts.

Guy Salama and Seong-min Hwang

Curr Protoc Cytom. 2009 Jul;Chapter 12:Unit 12.17.
Isolated heart
(guinea pig)
VSD
(PGH I)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Inhomogeneous distribution of action potential characteristics in the rabbit sino-atrial node revealed by voltage imaging.

Haruko Masumiya, Yoshitaka Oku and Yasumasa Okada

J Physiol Sci. 2009 May;59(3):227-41.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Fusion of optical imaging and MRI for the evaluation and adjustment of macroscopic models of cardiac electrophysiology: a feasibility study.

Mihaela Pop, Maxime Sermesant, Damien Lepiller, Michael V. Truong, Elliot R. McVeigh, Eugene Crystal, Alexander Dick, Herve Delingette, Nicholas Ayache and Graham A. Wright

Med Image Anal. 2009 Apr;13(2):370-80.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation.

Boyoung Joung, Liang Tang, Mitsunori Maruyama, Seongwook Han, Zhenhui Chen, Marcelle Stucky, Larry R. Jones, Michael C. Fishbein, James N. Weiss, Peng-Sheng Chen and Shien-Fong Lin

Circulation. 2009 Feb 17;119(6):788-96.
Isolated heart
(mongrel dog)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Cardioprotective effects of propofol in isolated ischemia-reperfused guinea pig hearts: role of KATP channels and GSK-3beta.

Noriko Kamada, Noriaki Kanaya, Naoyuki Hirata, Saori Kimura and Akiyoshi Namiki

Can J Anaesth. 2008 Sep;55(9):595-605.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
Superiority of biphasic over monophasic defibrillation shocks is attributable to less intracellular calcium transient heterogeneity.

Gyo-Seung Hwang, Liang Tang, Boyoung Joung, Norishige Morita, Hideki Hayashi, Hrayr S. Karagueuzian, James N. Weiss, Shien-Fong Lin and Peng-Sheng Chen

J Am Coll Cardiol. 2008 Sep 2;52(10):828-35.
Isolated heart
(rabbit)
VSD
(RH-237)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
(dual camera)
Abnormal Myocardial and Coronary Vasculature Development in Experimental Pypoxia.

Ondrej Nanka, Petra Krizova, Michal Fikrle, Michal Tuma, Milan Blaha, Milos Grim and David Sedmera

Anat Rec (Hoboken). 2008 Oct;291(10):spc1.
Isolated embryonic heart
(Japanese quail)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Connexin40 Imparts Conduction Heterogeneity to Atrial Tissue.

David E. Leaf, Jonathan E. Feig, Carolina Vasquez, Pamela L. Riva, Cindy Yu, Joshua M. Lader, Andrianos Kontogeorgis, Elvera L. Baron, Nicholas S. Peters, Edward A. Fisher, David E. Gutstein and Gregory E. Morley

Circ Res. 2008 Jul 3. [Epub ahead of print]
Isolated heart
(mouse)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Burst Emergence of Intracellular Ca2+ Waves Evokes Arrhythmogenic Oscillatory Depolarization via the Na+-Ca2+ Exchanger Simultaneous Confocal Recording of Membrane Potential and Intracellular Ca2+ in the Heart

Katsuji Fujiwara, Hideo Tanaka, Hiroki Mani, Takuo Nakagami and Tetsuro Takamatsu

Circ Res. 2008 Aug 29;103(5):509-18. Epub 2008 Jul 17.
Isolated heart
(rat)
VSD
(RH-237)

CaSD
(Fluo-4)
MiCAM02
Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

Michael Brunner, Xuwen Peng, Gong Xin Liu, Xiao-Qin Ren, Ohad Ziv, Bum-Rak Choi, Rajesh Mathur, Mohammed Hajjiri, Katja E. Odening, Eric Steinberg, Eduardo J. Folco, Ekatherini Pringa, Jason Centracchio, Roland R. Macharzina, Tammy Donahay, Lorraine Schofield, Naveed Rana, Malcolm Kirk, Gary F. Mitchell, Athena Poppas, Manfred Zehender and Gideon Koren

J Clin Invest. 2008 June 2; 118(6): 2246?2259.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Mechanisms underlying increased right ventricular conduction sensitivity to flecainide challenge

Rengasayee Veeraraghavan and Steven Poelzing

Cardiovasc Res. 2008 Mar 1;77(4):749-56.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
An Experimental Framework to Validate 3D Models of Cardiac Electrophysiology Via Optical Imaging and MRI

Mihaela Pop, Maxime Sermesant, Desmond Chung, Garry Liu, Elliot R. McVeigh, Eugene Crystal and Graham A. Wright

Lecture Notes in Computer Science Publisher Springer Berlin / Heidelberg Volume 4466/2007; pages 100-109.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Imaging ventricular fibrillation.

Guy Salama and Bum-Rak Choi

J Electrocardiol. 2007 Nov-Dec;40:S56-61.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Spatially discordant voltage alternans cause wavebreaks in ventricular fibrillation.

Bum-Rak Choi, Woncheol Jang and Guy Salama

Heart Rhythm. 2007 August; 4(8): 1057-1068.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia.

Wilhelm Roell, Thorsten Lewalter, Philipp Sasse, Yvonne N. Tallini, Bum-Rak Choi, Martin Breitbach, Robert Doran, Ulrich M. Becher, Seong-Min Hwang, Toktam Bostani, Julia von Maltzahn, Andreas Hofmann, Shaun Reining, Britta Eiberger, Bethann Gabris, Alexander Pfeifer, Armin Welz, Klaus Willecke, Guy Salama, Jan W. Schrickel, Michael I. Kotlikoff and Bernd K. Fleischmann

Nature. 2007 Dec 6;450(7171):819-24.
In VIvo heart
(mouse)
GGCaMP2MiCAM ULTIMA
Optical Mapping of Langendorff Perfused Human Hearts: Establishing a Model for the Study of Ventricular Fibrillation in Humans.

Kumaraswamy Nanthakumar, José Jalife, Stéphane Massé, Eugene Downar, Mihaela Pop, John Asta, Heather Ross, Vivek Rao, Sergey Mironov, Elias Sevaptsidis, Jack Rogers, Graham Wright and Rajesh Dhopeshwarkar

Am J Physiol Heart Circ Physiol. 2007 Mar 16;
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
MiCAM02
Heterogeneous ventricular chamber response to hypokalemia and inward rectifier potassium channel blockade underlies bifurcated T wave in guinea pig.

Steven Poelzing and Rengasayee Veeraraghavan

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3043-51.
Isolated heart
(guinea pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Stereo Reconstruction of the Epicardium for Optical Fluorescence Imaging.

Desmond Chung, Mihaela Pop, Maxime Sermesant and Graham A. Wright

MICCAI 2006 Workshop on Biophotonics Imaging for Diagnostics and Treatment. 2006 October 6; P33-40.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM02
(dual camera)
Pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique functionally integrates with the host heart, in vivo.

Akira Furuta, Shunichiro Miyoshi, Yuji Itabashi, Tatsuya Shimizu, Shinichiro Kira, Keiko Hayakawa, Nobuhiro Nishiyama, Kojiro Tanimoto, Yoko Hagiwara, Toshiaki Satoh, Keiichi Fukuda, Teruo Okano and Satoshi Ogawa

Circ Res. 2006 Mar 17;98(5):705-12.
Isolated heart
Cell sheet
(rat)
VSD
(Di-4-ANEPPS)
MiCAM01
Interactions between paced wavefronts and monomorphic ventricular tachycardia: implications for antitachycardia pacing.

Israel A. Byrd, Matthew W. Kay and Andrew E. Pollard

J Cardiovasc Electrophysiol. 2006 Oct;17(10):1129-39.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM01
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2

Yvonne N. Tallini, Masamichi Ohkura, Bum-Rak Choi, Guangju Ji, Keiji Imoto, Robert Doran, Jane Lee, Patricia Plan, Jason Wilson, Hong-Bo Xin, Atsushi Sanbe, James Gulick, John Mathai, Jeffrey Robbins, Guy Salama, Junichi Nakai and Michael I. Kotlikoff

Proc Natl Acad Sci USA. 2006 Mar 21;103(12):4753-8. Epub 2006 Mar 13.
In VIvo heart
(mouse)
GCaMP2MiCAM ULTIMA
Properties of new, long-wavelength, voltage-sensitive dyes in the heart.

Guy Salama, Bum-Rak Choi, Ghassan Azour, Mitra Lavasani, Vasil Tumbev, Brian M. Salzberg, Michael J. Patrick, Lauren A. Ernst and Alan S. Waggoner

J Membr Biol. 2005 Nov;208(2):125-40.
Isolated heart
(guinea pig, rabbit, mouse)
VSD
(PGH I-VII)
MiCAM ULTIMA
Termination of spiral waves during cardiac fibrillation via shock-induced phase resetting.

Richard A Gray and Nipon Chattipakorn

PNAS. 2005 Mar 29;102(13):4672-7.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM01
Optical Imaging of the Heart.

Igor R. Efimov, Vladimir P. Nikolski and Guy Salama.

Circulation Research 2004 Jul 9;95(1):21-33.
Isolated heart
(guinea pig)
VSDMiCAM ULTIMA
Three-dimensional surface reconstruction and panoramic optical mapping of large hearts.

Matthew W Kay, Philip M Amison and Jack M Rogers

IEEE Transactions on Biomedical Engineering, 2004 Jul;51(7):1219-29
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM01
Effect of shock-induced changes in transmembrane potential on reentrant waves and outcome during cardioversion of isolated rabbit hearts.

Frederick G. Evans, Raymond E. Ideker and Richard A. Gray

J Cardiovasc Electrophysiol. 2002 Nov;13(11):1118-27.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM01
Effect of Action Potential Duration and Conduction Velocity Restitution and Their Spatial Dispersionon Alternans and the Stability of Arrhythmias.

Isabelle Banville and Richard A Gray.

J Cardiovasc Electrophysiol. 2002 Nov;13(11):1141-9.
Isolated heart
(rabbit)
VSD
(Di-4-ANEPPS)
MiCAM01
Anisotropic conduction properties in canine atria analyzed by high-resolution optical mapping: preferential direction of conduction block changes from longitudinal to transverse with increasing age.

Takahiro Koura, Motoki Hara, Susumu Takeuchi, Kenichi Ota, Yasumasa Okada, Shunichiro Miyoshi, Atsushi Watanabe, Kazumi Shiraiwa, Hideo Mitamura, Itsuo Kodama and Satoshi Ogawa

Circulation. 2002;105:2092
Isolated atrial tissueVSD
(Di-4-ANEPPS)
MiCAM01
Mechanism of Ventricular Defibrillation for Near-Defibrillation Threshold Shocks.

Nipon Chattipakorn, Isabelle Banville, Richard A Gray and Raymond E Ideker.

Circulation. 2001;104:1313.
Isolated heart
(pig)
VSD
(Di-4-ANEPPS)
MiCAM01
Spatial and temporal organization during cardiac fibrillation.

Richard A. Gray, Arkady M. Pertsov and Jose Jalife.

Nature, 392, 75-78 (1998)
Isolated heart
(rabbit, sheep)
VSD
(Di-4-ANEPPS)
MiCAM01

培養心筋論文 

合計:75

論文名サンプル色素イメージングシステム
NaV1.5 knockout in iPSCs: a novel approach to study NaV1.5 variants in a human cardiomyocyte environment.

Marion Pierre, Mohammed Djemai, Hugo Poulin, and Mohamed Chahine

Sci Rep. 2021; 11: 17168.
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) VSD
(Di-4-ANEPPS)

CaSD
(Rhod-2 AM)
MiCAM03
High-Throughput Drug Screening System Based on Human Induced Pluripotent Stem Cell-Derived Atrial Myocytes ∼ A Novel Platform to Detect Cardiac Toxicity for Atrial Arrhythmias.

Yayoi Honda, Jun Li, Aya Hino, Shinji Tsujimoto, and Jong-Kook Lee

Front Pharmacol. 2021 Aug 3;12:680618.
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) VSD
(FluoVolt)
MiCAM02
Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC.

Robert N. Hawthorne, Adriana Blazeski, Justin Lowenthal, Suraj Kannan, Roald Teuben, Deborah DiSilvestre, Justin Morrissette-McAlmon, Jeffrey E. Saffitz, Kenneth R. Boheler, Cynthia A. James, Stephen P. Chelko, Gordon Tomaselli and Leslie Tung

J. Clin. Med. 2021, 10(14), 3061;
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) VSD
(Di-4-ANEPPS)

CaSD
(Rhod-2 AM)
MiCAM ULTIMA
A 3-D Human Model of Complex Cardiac Arrhythmias.

Kenneth Williams, Timothy Liang, Stéphane Massé, Safwat Khan, Rupal Hatkar, Gordon Keller, Kumaraswamy Nanthakumar, Sara S. Nunes

Acta Biomaterialia Available online 10 March 2021
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) CaSDMiCAM ULTIMA
Human iPSC engineered cardiac tissue platform faithfully models important cardiac physiology.

Willem J. de Lange, Emily T. Farrell, Caroline R. Kreitzer, Derek R. Jacobs, Di Lang, Alexey V. Glukhov, and J. Carter Ralphe

Am J Physiol Heart Circ Physiol. 2021 Feb 19.
Human induced pluripotent stem cells (hiPSC-CM)CaSDMiCAM ULTIMA
Myocardial repair of bioengineered cardiac patches with decellularized placental scaffold and human-induced pluripotent stem cells in a rat model of myocardial infarction.

Yu Jiang, Si-Jia Sun, Zhe Zhen, Rui Wei, Nannan Zhang, Song-Yan Liao & Hung-Fat Tse

Stem Cell Res Ther 12, 13 (2021).
Bioengineered cardiac patch (human-induced pluripotent stem cell-derived cardiomyocytes: hiPSC-CMs)CaSD
(Fura-2 AM)
MiCAM ULTIMA
iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities.

Hugo Poulin, Aurélie Mercier, Mohammed Djemai, Valérie Pouliot, Isabelle Deschenes, Mohamed Boutjdir, Jack Puymirat & Mohamed Chahine

Scientific Reports volume 11, Article number: 2500 (2021)
Induced pluripotent stem-derived cardiomyocytes (iPSC-CMs)VSD
(Di-4-ANEPPS)
MiCAM03
Scaffold-Mediated Developmental Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Are Preserved After External Support Removal.

Jun Li, Jong-Kook Lee, Keiko Miwa, Yuki Kuramoto, Kiyoshi Masuyama, Hideki Yasutake, Satoki Tomoyama, Hiroyuki Nakanishi, and Yasushi Sakata

Front Cell Dev Biol. 2021; 9: 591754.
Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs)VSD
(FluoVolt)
MiCAM02
Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues.

Andy On-Tik Wong, Bimal Gurung, Wing Sum Wong, Suet Yee Mak, Wan Wai Tse, Chloe M. Li, Deborah K. Lieu, Kevin D. Costa, Ronald A. Li, and Roger J. Hajjar

J Mol Cell Cardiol. 2021 Apr; 153: 106?110.
Human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)?MiCAM03
Local hyperactivation of L-type Ca2+ channels increases spontaneous Ca2+ release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats.

Roman Y. Medvedev, Jose L. Sanchez-Alonso, Catherine A. Mansfield, Aleksandra Judina, Alice J. Francis, Christina Pagiatakis, Natalia Trayanova, Alexey V. Glukhov, Michele Miragoli, Giuseppe Faggian & Julia Gorelik

Scientific Reports volume 11, Article number: 4840 (2021)
Isolated myocytesCaSD
(Fluo-4 AM)
MiCAM ULTIMA
Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium.

Cassady E. Rupert, Tae Yun Kim, Bum-Rak Choi, and Kareen L. K. Coulombe

Stem Cells Int. 2020; 2020: 9363809.
Engineered cardiac tissuesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity.

Jessica M. Miller, Moustafa H. Meki, Qinghui Oua, Sharon A. George, Anna Gams, Riham R.E. Abouleisa, Xian-Liang Tang, Brooke M. Ahern, Guruprasad A. Giridharan, Ayman El-Baz, Bradford G. Hill, Jonathan Satin, Daniel J.Conklin, Javid Moslehi, Roberto Bolli, Alexandre J.S. Ribeiro, Igor R. Efimov, Tamer M.A. Mohamed

Toxicology and Applied Pharmacology, Volume 406, 2020,115213
Cultured heart sliceVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts.

B. N. Napiwocki, D. Lang, A. Stempien, J. Zhang, R. Vaidyanathan, J. C. Makielski, L. L. Eckhardt, A. V. Glukhov, T. J. Kamp, W. C. Crone

Biotechnology and Bioengineering. 2021; 118: 442? 452.
Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs)CaSD
(Rhod-2 AM)
MiCAM ULTIMA
The proarrhythmic features of pathological cardiac hypertrophy in neonatal rat ventricular cardiomyocyte cultures

Zeinab Neshati, Martin J Schalij, Antoine A F de Vries

J Appl Physiol (1985). 2020 Mar 1;128(3):545-553.
Neonatal rat ventricular cardiomyocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Adrenoceptor Responses in Human Embryonic Stem Cell-Derived Cardiomyocytes: a Special Focus on Electrophysiological Property.

Weiwei Jiang, Xingjian Hu, Fei Li, Geng Li, Yin Wang

J Pharmacol Exp Ther. 2020 Jun;373(3):429-437.
Human embryonic stem cell]derived cardiomyocytes (hESC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Single]Cell Transcriptomics of Engineered Cardiac Tissues From Patient]Specific Induced Pluripotent Stem Cell?Derived Cardiomyocytes Reveals Abnormal Developmental Trajectory and Intrinsic Contractile Defects in Hypoplastic Right Heart Syndrome.

Yin]Yu Lam, Wendy Keung, Chun]Ho Chan, Lin Geng, Nicodemus Wong, David Brenière]Letuffe, Ronald A. Li and Yiu]Fai Cheung

J Am Heart Assoc. 2020 Oct 20; 9(20): e016528.
Human cardiac anisotropic sheetVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients.

Andy On-Tik Wong, Nicodemus Wong, Lin Geng, Maggie Zi-ying Chow, Eugene K. Lee, Hongkai Wu, Michelle Khine, Chi-Wing Kong, Kevin D. Costa, Wendy Keung, Yiu-Fai Cheung, and Ronald A. Li

Front Physiol. 2020; 11: 165.
Human ventricular cardiac anisotropic sheet preparations VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Functional Properties of Engineered Heart Slices Incorporating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Adriana Blazeski, Justin Lowenthal, Renjun Zhu, Jourdan Ewoldt, Kenneth R. Boheler, and Leslie Tung

Theranostics. 2019; 9(24): 7222?7238.
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variation.

Sarkawt Hamad, Daniel Derichsweiler, Symeon Papadopoulos, Filomain Nguemo, Tomo Šarić, Agapios Sachinidis, Konrad Brockmeier, Jürgen Hescheler, Bastiaan J Boukens, and Kurt Pfannkuche

Theranostics. 2019; 9(24): 7222?7238.
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes.

Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun Zhu, Sharon Gerecht, Gordon Tomaselli, Leslie Tung

Tissue Eng Part A. 2019 May;25(9-10):725-735.
Engineered heart slicesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Correlation between frataxin expression and contractility revealed by in vitro Friedreich's ataxia cardiac tissue models engineered from human pluripotent stem cells.

Andy On-Tik Wong, Gabriel Wong, Michael Shen, Maggie Zi-Ying Chow, Wan Wai Tse, Bimal Gurung, Suet Yee Mak, Deborah K Lieu, Kevin D Costa, Camie W Chan, Alain Martelli, Joseph F Nabhan, Ronald A Li

Stem Cell Res Ther. 2019 Jul 8;10(1):203.
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Contribution of potassium channels to action potential repolarization of human embryonic stem cell-derived cardiomyocytes.

Yin Wang, Renjun Zhu, Leslie Tung

Br J Pharmacol. 2019 Aug;176(15):2780-2794.
Human embryonic stem cell]derived cardiomyocytes (hESC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Enhancement of human iPSC-derived cardiomyocyte maturation by chemical conditioning in a 3D environment.

Chen Yu Huang, Rebeca Peres Moreno Maia-Joca, Chin Siang Ong, Ijala Wilson, Deborah DiSilvestre, Gordon F Tomaselli, Daniel H Reich

J Mol Cell Cardiol. 2020 Jan;138:1-11.
Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An In vitro Disease Model of Atrial Arrhythmias.

Hiroyuki Nakanishi, Jong-Kook Lee, Keiko Miwa, Kiyoshi Masuyama, Hideki Yasutake, Jun Li, Satoki Tomoyama, Yayoi Honda, Jiro Deguchi, Shinji Tsujimoto, Kyoko Hidaka, Shigeru Miyagawa, Yoshiki Sawa, Issei Komuro, Yasushi Sakata

Front Physiol. 2019 Jun 27;10:818.
Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs)VSD
(FluoVolt)
MiCAM02
Multiparametric slice culture platform for the investigation of human cardiac tissue physiology.

Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, Igor R Efimov

Prog Biophys Mol Biol. 2019 Jul;144:139-150.
Cultured murine atria and human slicesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.

Anna M. D. Végh, A. Dénise Den Haan, Lucía Cócera Ortega, Arie O. Verkerk, Joost P. G. Sluijter, Diane Bakker, Shirley Van Amersfoorth, Toon A. B. Van Veen, Mischa Klerk, Jurgen Seppen, Jacques M. T. De Bakker, Vincent M. Christoffels, Dirk Geerts, Marie José T. H. Goumans, Hanno L. Tan and Gerard J. J. Boink

Molecules. 2019 Jan 5;24(1). pii: E181.
Organ explant culturesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy using Plakophilin-2 Mutant Myocytes.

Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun ZhuProf, Sharon Gerecht, Gordon Tomaselli and Leslie Tung

Tissue Eng Part A. 2018 Dec 6.
Engineered heart slicesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system.

Rupamanjari Majumder, Iolanda Feola, Alexander S Teplenin, Antoine AF de Vries, Alexander V Panfilov and Daniel A Pijnappels

Elife. 2018 Sep 27;7. pii: e41076.
Neonatal rat atrial cardiomyocytesVSD
(Di-4-ANBDQBS)
MiCAM ULTIMA
A tissue-engineered scale model of the heart ventricle.

Luke A. MacQueen, Sean P. Sheehy, Christophe O. Chantre, John F. Zimmerman, Francesco S. Pasqualini, Xujie Liu, Josue A. Goss, Patrick H. Campbell, Grant M. Gonzalez, Sung-Jin Park, Andrew K. Capulli, John P. Ferrier, T. Fettah Kosar, L. Mahadevan, William T. Pu and Kevin Kit Parker

Nature Biomedical Engineering (2018). Published: 23 July 2018
Neonatal rat ventricular myocytesCaSD
(Rhod-2)
MiCAM ULTIMA
Multiparametric slice culture platform for the investigation of human cardiac tissue physiology.

Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T. Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, and Igor R. Efimov

Prog Biophys Mol Biol. 2018 Jun 27. pii: S0079-6107(18)30012-9.
Cultured mouse atrial tissue and human cardiac slicesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Paradoxical Onset of Arrhythmic Waves from Depolarized Areas in Cardiac Tissue Due to Curvature-Dependent Instability.

Alexander S. Teplenin, Hans Dierckx, Antoine A. F. de Vries, Daniël A. Pijnappels, and Alexander V. Panfilov

Phys Rev X. 2018 Jun 26; 8(2): 021077.
Neonatal rat ventricular myocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.

Ronald A.Li, Wendy Keung, Timothy J. Cashman, Peter C. Backeris, Bryce V.Johnson, Evan S.Bardot, Andy O.T. Wong, Patrick K.W. Chan, Camie W.Y. Chan, Kevin D. Costa

Biomaterials. 2018 May;163:116-127
Human ventricle-like cardiac organoid chamberVSD
(Di-8-ANEPPS)

CaSD
(X-rhod-1 AM)
MiCAM ULTIMA
Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue.

Daisuke Sasaki, Katsuhisa Matsuura, Hiroyoshi Seta, Yuji Haraguchi, Teruo Okano, Tatsuya Shimizu

PLoS One. 2018 May 23;13(5):e0198026.
Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs)CaSD
(Fluo-8)
MiCAM ULTIMA
Resolving Myocardial Activation With Novel Omnipolar Electrograms.

Stéphane Massé, Karl Magtibay, Nicholas Jackson, John Asta, Marjan Kusha, Boyang Zhang, Ram Balachandran, Milica Radisic, D. Curtis Deno, and Kumaraswamy Nanthakumar

Circ Arrhythm Electrophysiol. 2016 Jul;9(7):e004107. doi: 10.1161/CIRCEP.116.004107.
MonolayersCaSD
(Fluo-4 AM)
MiCAM ULTIMA
Variability of Action Potentials Within and Among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells.

Renjun Zhu, Michal A. Millrod, Elias T. Zambidis, and Leslie Tung

Sci Rep. 2016 Jan 5;6:18544. doi: 10.1038/srep18544.
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing.

Johan U. Lind, Travis A. Busbee, Alexander D. Valentine, Francesco S. Pasqualini, Hongyan Yuan, Moran Yadid, Sung-Jin Park, Arda Kotikian, Alexander P. Nesmith, Patrick H. Campbell, Joost J. Vlassak, Jennifer A. Lewis and Kevin K. Parker

Nat Mater. 2016 Oct 24. doi: 10.1038/nmat4782. [Epub ahead of print]
Neonatal rat ventricular myocytesVSD
(RH-237)
MiCAM ULTIMA
Optogenetic Engineering of Atrial Cardiomyocytes.

Iolanda Feola, Alexander Teplenin, Antoine A. F. de Vries, Daniël A. Pijnappels

Methods Mol Biol. 2016;1408:319-31. doi: 10.1007/978-1-4939-3512-3_22.
Atrial cardiomyocytes (aCMCs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity.

Angie M. Y. Shum, Hui Che, Andy On-Tik Wong, Chenzi Zhang, Hongkai Wu, Camie W. Y. Chan, Kevin Costa, Michelle Khine, Chi-Wing Kong, Ronald A. Li

Adv Mater. 2016 Nov 2. doi: 10.1002/adma.201602448. [Epub ahead of print]
Human ventricular cardiac anisotropic sheet (hvCAS)VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Islands of spatially discordant APD alternans underlie arrhythmogenesis by promoting electrotonic dyssynchrony in models of fibrotic rat ventricular myocardium

Rupamanjari Majumder, Marc C. Engels, Antoine A. F. de Vries, Alexander V. Panfilov, and Daniël A. Pijnappels

Sci Rep. 2016; 6: 24334. Published online 2016 Apr 13. doi: 10.1038/srep24334
MonolayersVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Electroactive polyurethane/siloxane derived from castor oil as a versatile cardiac patch, Part II: HL-1 cytocompatibility and electrical characterizations.

Nafiseh Baheiraei, Reza Gharibi, Hamid Yeganeh, Michele Miragoli, Nicolò Salvarani, Elisa Di Pasquale and Gianluigi Condorelli

J Biomed Mater Res A. 2016 Jan 28. doi: 10.1002/jbm.a.35669. [Epub ahead of print]
HL-1 monolayersCaSD
(Fluo-4 AM)
MiCAM ULTIMA
The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts.

Francisca Schultz, Alveera Hasan, Anita Alvarez-Laviada, Michele Miragoli, Navneet Bhogal, Sarah Wells, Claire Poulet, Jenny Chambers, Catherine Williamson and Julia Gorelik

Prog Biophys Mol Biol. 2016 Jan 8. pii: S0079-6107(16)00005-5. doi: 10.1016/j.pbiomolbio.2016.01.003. [Epub ahead of print]
Isolated cardiomyocytes CaSD
(Fluo-4 AM)

VSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes.

Michele Miragoli, Jose L. Sanchez-Alonso, Anamika Bhargava, Peter T. Wright, Markus Sikkel, Sophie Schobesberger, Ivan Diakonov, Pavel Novak, Alessandra Castaldi, Paola Cattaneo, Alexander R. Lyon, Max J. Lab, Julia Gorelik

Cell Rep. 2016 Jan 5;14(1):140-51. doi: 10.1016/j.celrep.2015.12.014. Epub 2015 Dec 24.
Isolated cardiomyocytes CaSD
(Fluo-4 AM)
MiCAM ULTIMA
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy.

Bo Lin, Yang Li, Lu Han, Aaron D. Kaplan, Ying Ao, Spandan Kalra, Glenna C. L. Bett, Randall L. Rasmusson, Chris Denning and Lei Yang

Dis Model Mech. 2015 May;8(5):457-66. doi: 10.1242/dmm.019505. Epub 2015 Mar 19.
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs)CaSD
(Rhod-2 AM)
MiCAM ULTIMA
Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes.

Alexey V. Glukhov, Marina Balycheva, Jose L. Sanchez-Alonso, Zeki Ilkan, Anita Alvarez-Laviada, Navneet Bhogal, Ivan Diakonov, Sophie Schobesberger, Markus B. Sikkel, Anamika Bhargava, Giuseppe Faggian, Prakash P. Punjabi, Steven R. Houser and Julia Gorelik

Circulation. 2015 Oct 8. pii: CIRCULATIONAHA.115.018131. [Epub ahead of print]
Human atrial myocytesCaSD
(Fluo-4 AM)
MiCAM ULTIMA
Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs.

Gaopeng Chen, Sen Li, Ioannis Karakikes, Lihuan Ren, Maggie Zi-Ying Chow, Anant Chopra, Wendy Keung, Bin Yan, Camie WY Chan, Kevin D. Costa, Chi-Wing Kong, Roger J. Hajjar, Christopher S. Chen and Ronald A. Li

Circ Arrhythm Electrophysiol. 2015 Feb;8(1):193-202. doi: 10.1161/CIRCEP.114.002049. Epub 2014 Dec 10.
hESC/iPSC-vCMs CaSD
(X-Rhod-1 AM)
MiCAM ULTIMA
Combining TGF-ƒÀ signal inhibition and connexin43 silencing for iPSC induction from mouse cardiomyocytes

Ping Dai, Yoshinori Harada, Hitoshi Miyachi, Hideo Tanaka, Satsuki Kitano, Tetsuya Adachi, Tomoyuki Suzuki, Hitoshi Hino and Tetsuro Takamatsu

Sci Rep. 2014; 4: 7323.
Cardiomyocytes derived from siPSCsCaSD
(Fluo-4 AM)
MiCAM02
Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes.

Brian O. Bingen, Marc C. Engels, Martin J. Schalij, Wanchana Jangsangthong, Zeinab Neshati, Iolanda Feola, Dirk L. Ypey, Saïd F.A. Askar, Alexander V. Panfilov, Daniël A. Pijnappels and Antoine A.F. de Vries

Cardiovasc Res. 2014 Jul 31. pii: cvu179. [Epub ahead of print]
Neonatal rat atrial cardiomyocyte monolayersVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia.

C. Ian Spencer, Shiro Baba, Kenta Nakamura, Ethan A. Hua, Marie A.F. Sears, Chi-cheng Fu, Jianhua Zhang, Sadguna Balijepalli, Kiichiro Tomoda, Yohei Hayashi, Paweena Lizarraga, Julianne Wojciak, Melvin M. Scheinman, Katriina Aalto-Setälä, Jonathan C. Makielski, Craig T. January, Kevin E. Healy, Timothy J. Kamp, Shinya Yamanaka, Bruce R. Conklinemail

Stem Cell Reports. 2014 Aug 12;3(2):269-281.
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs)CaSD
(Fluo-4 AM)
MiCAM02
Quality metrics for stem cell-derived cardiac myocytes.

Sean P. Sheehy, Francesco Pasqualini, Anna Grosberg, Sung Jin Park, Yvonne Aratyn-Schaus and Kevin Kit Parker

Stem Cell Reports. 2014 Mar 6;2(3):282-94. doi: 10.1016/j.stemcr.2014.01.015. eCollection 2014.
Neonatal mouse ventricular cardiomyocytesVSD
(RH-237)
MiCAM ULTIMA
Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State.

Weining Bian, Nima Badie, Herman D. Himel IV and Nenad Bursac

Biomaterials. 2014 Apr;35(12):3819-28. doi: 10.1016/j.biomaterials.2014.01.045. Epub 2014 Feb 6.
Neonatal rat ventricular cardiomyocytesCaSD
(Rhod-2)
MiCAM ULTIMA
Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias.

Jiaxian Wang, Aaron Chen, Deborah K. Lieu, Ioannis Karakikes, Gaopeng Chen, Wendy Keung, Camie W. Chan, Roger J. Hajjar, Kevin D. Costa, Michelle Khine and Ronald A. Li

Biomaterials. 2013 Nov;34(35):8878-86. doi: 10.1016/j.biomaterials.2013.07.039. Epub 2013 Aug 12.
Human
pluripotent stem cell-derived ventricular cardiomyocytes (hPSC-CMs)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State.

Ji-Dong Fu, Nicole R. Stone, Lei Liu, C. Ian Spencer, Li Qian, Yohei Hayashi, Paul Delgado-Olguin, Sheng Ding, Benoit G. Bruneau and Deepak Srivastava

Stem Cell Reports, Volume 1, Issue 3, 235-247, 22 August 2013
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs)CaSD
(Fluo-4 AM)
MiCAM02
CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia.

Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G and Priori SG

Cell Death Dis. 2013 Oct 10;4:e843. doi: 10.1038/cddis.2013.369.
iPSC-derived cardiac cellsCaSD
(Fluo-4 AM)
MiCAM ULTIMA
Repopulation of decellularized mouse heart with human induced pluripotent stem cell-derived cardiovascular progenitor cells.

Tung-Ying Lu, Bo Lin, Jong Kim, Mara Sullivan, Kimimasa Tobita, Guy Salama and Lei Yang

Nat Commun. 2013 Aug 14;4:2307. doi: 10.1038/ncomms3307.
Human induced pluripotent stem cell-derived
cardiovascular progenitor cells
CaSD
(Rhod-2)
MiCAM ULTIMA
Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes.

Sara S Nunes, Jason W Miklas, Jie Liu, Roozbeh Aschar-Sobbi, Yun Xiao, Boyang Zhang, Jiahua Jiang, Stéphane Massé, Mark Gagliardi, Anne Hsieh, Nimalan Thavandiran, Michael A Laflamme, Kumaraswamy Nanthakumar, Gil J Gross, Peter H Backx, Gordon Keller and Milica Radisic

Nat Methods. 2013 Aug;10(8):781-7. doi: 10.1038/nmeth.2524. Epub 2013 Jun 23.
Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Fibroblast KATP Currents Modulate Myocyte Electrophysiology in Infarcted Hearts.

Najate Benamer, Carolina Vasquez, Vanessa M Mahoney, Maximilian J Steinhardt, William A Coetzee, and Gregory E Morley

Am J Physiol Heart Circ Physiol. 2013 May;304(9):H1231-9. doi: 10.1152/ajpheart.00878.2012. Epub 2013 Feb 22.
MonolayerVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Oscillation in Cycle Length Induces Transient Discordant and Steady-State Concordant Alternans in the Heart.

Seth H. Weinberg and Leslie Tung

PLoS One. 2012;7(7):e40477. Epub 2012 Jul 5.
MonolayerVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
ILK Induces Cardiomyogenesis in the Human Heart.

Alexandra Traister, Shabana Aafaqi, Stephane Masse, Xiaojing Dai, Mark Li, Aleksander Hinek, Kumaraswamy Nanthakumar, Gregory Hannigan and John G. Coles

Med Image Anal. 2012 Feb;16(2):505-23. Epub 2011 Dec 6.
Human fetal cardiomyocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Functional Scaffold-Free 3D Cardiac Microtissues: a Novel Model for the Investigation of Heart Cells.

Bethany R Desroches, Peng Zhang, Bum-Rak Choi, Michelle E King, Angel E Maldonado, Weiyan Li, Adam Rago, Gong-Xin Liu, Nandan Nath, Kathryn M Hartmann, Bryant Yang, Gideon Koren, Jeffrey R Morgan and Ulrike Mende

Am J Physiol Heart Circ Physiol. 2012 Mar 16. [Epub ahead of print]
Neonatal rat cardiomyocytesVSD
(RH-237)
MiCAM ULTIMA
High-purity enrichment of functional cardiovascular cells from human iPS cells.

Bo Lin, Jong Kim, Yanxin Li, Haiying Pan, Xonia Carvajal-Vergara, Guy Salama, Tao Cheng, Yong Li, Cecilia W. Lo and Lei Yang

Cardiovasc Res. 2012 Aug 1;95(3):327-35. Epub 2012 Jun 6.
Human iPSC-derived cardiovascular cellsCaSD
(Rhod-2)
MiCAM ULTIMA
Connexin43 silencing in myofibroblasts prevents arrhythmias in myocardial cultures: role of maximal diastolic potential.

Saïd F. Askar, Brian O. Bingen, Jim Swildens, Dirk L. Ypey, Arnoud van der Laarse, Douwe E. Atsma, Katja Zeppenfeld, Martin J. Schalij, Antoine A. de Vries and Daniël A. Pijnappels

Cardiovasc Res. 2012 Mar 1;93(3):434-44. Epub 2011 Dec 22.
Primary ventricular cardiomyocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives.

Aaron Chen, Deborah K. Lieu, Lauren Freschauf, Valerie Lew, Himanshu Sharma, Jiaxian Wang, Diep Nguyen, Ioannis Karakikes, Roger J. Hajjar, Ajay Gopinathan, Elliot Botvinick, Charless C. Fowlkes, Ronald A. Li and Michelle Khine

Adv Mater. 2011 Dec 22;23(48):5785-91. doi: 10.1002/adma.201103463. Epub 2011 Nov 8.
Human embryonic stem cells-derived cardiomyocytes (hESC-CMs)VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts.

Arti A. Ramkisoensing, Daniël A. Pijnappels, Saïd F. A. Askar, Robert Passier, Jim Swildens, Marie José Goumans, Cindy I. Schutte, Antoine A. F. de Vries, Sicco Scherjon, Christine L. Mummery, Martin J. Schalij and Douwe E. Atsma

PLoS One. 2011;6(9):e24164. Epub 2011 Sep 9.
Neonatal rat ventricular cardiomyocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart.

Michele Miragoli, Siti H. Sheikh Abdul Kadir, Mary N. Sheppard, Nicoló Salvarani, Matilda Virta, Sarah Wells, Max J. Lab, Viacheslav O. Nikolaev, Alexey Moshkov, William M. Hague, Stephan Rohr, Catherine Williamson and Julia Gorelik

Hepatology. 2011 Oct;54(4):1282-92. doi: 10.1002/hep.24492. Epub 2011 Aug 1.
MonolayerVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Antiproliferative treatment of myofibroblasts prevents arrhythmias in vitro by limiting myofibroblast-induced depolarization.

Saïd F.A. Askar, Arti A. Ramkisoensing, Martin J. Schalij, Brian O. Bingen, Jim Swildens, Arnoud van der Laarse, Douwe E. Atsma, Antoine A.F. de Vries, Dirk L. Ypey and Daniël A. Pijnappels

Cardiovasc Res. 2011 Feb 2. [Epub ahead of print]
Neonatal rat ventricular cardiomyocytesVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Enhanced fibroblast-myocyte interactions in response to cardiac injury.

Carolina Vasquez, Poornima Mohandas, Karen L. Louie, Najate Benamer, Ashwini C. Bapat and Gregory E. Morley

Circ Res. 2010 Oct 15;107(8):1011-20. Epub 2010 Aug 12.
MonolayerVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.

Masaki Ieda, Ji-Dong Fu, Paul Delgado-Olguin, Vasanth Vedantham, Yohei Hayashi, Benoit G. Bruneau and Deepak Srivastava

Cell. 2010 Aug 6;142(3):375-86.
Cardiac fibroblast?derived induced cardiomyocytesCaSD
(Rhod-3)
MiCAM02
Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M2 Receptors in Neonatal Rat Cardiomyocytes.

Siti H. Sheikh Abdul Kadir, Michele Miragoli, Shadi Abu-Hayyeh, Alexey V. Moshkov, Qilian Xie, Verna Keitel, Viacheslav O. Nikolaev, Catherine Williamson and Julia Gorelik

PLoS One. 2010; 5(3): e9689.
Ventricular neonatal rat myocyteCaSD
(Fluo-4 AM)
MiCAM ULTIMA
Engineered heart tissue: a novel tool to study the ischemic changes of the heart in vitro.

Rajesh G. Katare, Motonori Ando, Yoshihiko Kakinuma and Takayuki Sato

PLoS One. 2010 Feb 17;5(2):e9275.
Engineered heart tissueVSD
(Di-4-ANEPPS)
MiCAM02
Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue.

Hannah Song, Charles Yoon, Steven J. Kattman, Jana Dengler, Stéphane Massé, Thushaanthini Thavaratnam, Mena Gewarges, Kumaraswamy Nanthakumar, Michael Rubart, Gordon M. Keller, Milica Radisic and Peter W. Zandstra

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3329-34.
Engineered heart tissueVSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Electrogram fractionation in murine HL-1 atrial monolayer model.

Karthikeyan Umapathy, Stephane Masse, Karolina Kolodziejska, George D. Veenhuyzen, Vijay S. Chauhan, Mansoor Husain, Talha Farid, Eugene Downar, Elias Sevaptsidis and Kumaraswamy Nanthakumar

Heart Rhythm. 2008 Jul;5(7):1029-35.
Monolayer
(HL-1)
VSD
(Di-4-ANEPPS)
MiCAM ULTIMA
Generation of reentrant arrhythmias by dominant-negative inhibition of connexin43 in rat cultured myocyte monolayers

Takuo Nakagami, Hideo Tanaka, Ping Dai, Shien-Fong Lin, Takuji Tanabe, Hiroki Mani, Katsuji Fujiwara, Hiroaki Matsubara and Tetsuro Takamatsu

Cardiovasc Res. 2008 Jul 1;79(1):70-9. Epub 2008 Mar 31.
MonolayerCaSD
(Fluo-4)
MiCAM02
Myofibroblasts induce ectopic activity in cardiac tissue.

Michele Miragoli, Nicolò Salvarani and Stephan Rohr

Circ Res. 2007 Oct 12;101(8):755-8.
MonolayerVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
Dynamic changes of cardiac conduction during rapid pacing.

Aleksandar A. Kondratyev, Julien G. C. Ponard, Adelina Munteanu, Stephan Rohr and Jan P. Kucera

Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1796-1811.
MonolayerVSD
(Di-8-ANEPPS)
MiCAM ULTIMA
A new method for manufacturing cardiac cell sheets using fibrin-coated dishes and its electrophysiological studies by optical mapping.

Yuji Itabashi, Shunichiro Miyoshi, Haruko Kawaguchi, Shinsuke Yuasa, Kojiro Tanimoto, Akira Furuta, Tatsuya Shimizu, Teruo Okano, Keiichi Fukuda and Satoshi Ogawa

Artif Organs. 2005 Feb;29(2):95-103.
Myocardial cell sheetsVSD
(Di-4-ANEPPS)
MiCAM01