- Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun ZhuProf, Sharon Gerecht, Gordon Tomaselli and Leslie Tung
Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy using Plakophilin-2 Mutant Myocytes.
- Zhen Wang, Lianguo Wang, Srinivas Tapa, Kent E. Pinkerton, Chao-Yin Chen and Crystal M. Ripplinger
Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model.
- Adam Connolly, Allen Kelly, Fernando O. Campos, Rachel Myles, Godfrey Smith and Martin J. Bishop
Ventricular Endocardial Tissue Geometry Affects Stimulus Threshold and Effective Refractory Period.
- Kedar K. Aras, Ndeye Rokhaya Faye, Brianna Cathey and Igor R. Efimov
Critical Volume of Human Myocardium Necessary to Maintain Ventricular Fibrillation.
- Rupamanjari Majumder, Iolanda Feola, Alexander S Teplenin, Antoine AF de Vries, Alexander V Panfilov and Daniel A Pijnappels
Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system.
- Virginie Dubes, David Benoist, François Roubertie, Stephen H. Gilbert, Marion Constantin, Sabine Charron, Delphine Elbes, Delphine Vieillot, Bruno Quesson, Hubert Cochet, Michel Haïssaguerre, Caroline Rooryck, Pierre Bordachar, Jean-Benoit Thambo, and Olivier Bernus
Arrhythmogenic Remodeling of the Left Ventricle in a Porcine Model of Repaired Tetralogy of Fallot.
- Yong Zhang, Lihua Sun, Lina Xuan, Zhenwei Pan, Xueling Hu, Hongyu Liu, Yunlong Bai, Lei Jiao, Zhange Li, Lina Cui, Xiaoxue Wang, Siqi Wang, Tingting Yu, Bingbing Feng, Ying Guo, Zonghong Liu, Weixin Meng, Hequn Ren, Jiyuan Zhu, Xuyun Zhao, Chao Yang, Ying Zhang, Chaoqian Xu, Zhiguo Wang, Yanjie Lu, Hongli Shan, and Baofeng Yang
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling.
- Jae Hyung Cho, Peter J. Kilfoil, Rui Zhang, Ryan E. Solymani, Catherine Bresee, Elliot M. Kang, Kristin Luther, Russell G. Rogers, Geoffrey de Couto, Joshua I. Goldhaber, Eduardo Marbán, and Eugenio Cingolani
Reverse electrical remodeling in rats with heart failure and preserved ejection fraction.
- Paul D. Pang, Katherina M. Alsina, Shuyi Cao, Amrita B. Koushik, Xander H.T. Wehrens and Thomas A. Cooper
CRISPR‐Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.
- Aida Olivan-Viguera, Angel Luis Garcia-Otin, Javier Lozano-Gerona, Edgar Abarca-Lachen, Ana J. Garcia-Malinis, Kirk L. Hamilton, Yolanda Gilaberte, Esther Pueyo, and Ralf Köhler
Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.
- Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, and Samuel C. Dudley Jr.
HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.
- Marine E. Martinez, Richard D. Walton, Jason D. Bayer, Michel Haïssaguerre, Edward J. Vigmond, Mélèze Hocini and Olivier Bernus
Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium.
- Taro Tenma, Hirofumi Mitsuyama, Masaya Watanabe, Naoya Kakutani, Yutaro Otsuka, Kazuya Mizukami, Rui Kamada, Masayuki Takahashi, Shingo Takada, Hisataka Sabe, Hiroyuki Tsutsui, and Hisashi Yokoshiki
Small-conductance Ca2+-activated K+ channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy.
Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H262-H272.
- Dolkun Rahmutula, Hao Zhang, Emily E Wilson and Jeffrey E Olgin
Absence of NPR-C Attenuates TGF-ß1 Induced Selective Atrial Fibrosis and Atrial Fibrillation.
- Daoyuan Si, Mohammed Ali Azam, Patrick F.H. Lai, Nima Zamiri, Galina Kichigina, John Asta, Stéphane Massé, Mahmoud M. Bokhari, Andreu Porta‐Sánchez, Christopher Labos, Huan Sun, Ping Yang and Kaumaraswamy Nanthakumar
Essential Role of RyR2 Phosphorylation in the Effect of Azumolene on Ventricular Arrhythmia Vulnerability in a Rabbit Heart Model.
- Rebecca Vicente Steijn, David Sedmera, Nico A. Blom, Monique Jongbloed, Alena Kvasilova, and Ondrej Nanka
Apoptosis and epicardial contributions act as complementary factors in remodeling of the atrioventricular canal myocardium and atrioventricular conduction patterns in the embryonic chick heart.
- Yen-Ling Sung, Chih-En Wu, Jhen-Yang Syu,Terry B.J.Kuo, Jai-YiLi, Chieh-Wen Chen, Ching-Hui Weng, Wei-Hsuan Hsu, Shih-Ann Chen, Yu-Feng Hu and Shien-Fong Lin
Effects of long-term exercise on arrhythmogenesis in aged hypertensive rats.
- Richard D. Walton, Ali Pashaei, Marine E. Martinez, Marion Constantin, Josselin Duchateau, Laura Bear, Caroline Cros, Caroline Pascarel-Auclerc, Yunbo Guo, David Benoist, Virginie Dubes, Ndeye Rokhaya Faye, Sebastien Chaigne, Sebastien Dupuis, Dominique Détaille, Line Pourtau, Philippe Pasdois, Fabien Brette, Julien Rogier, Louis Labrousse, Mélèze Hocini, Edward J. Vigmond, Michel Haïssaguerre and Olivier Bernus
Compartmentalized Structure of the Moderator Band Provides a Unique Substrate for Macroreentrant Ventricular Tachycardia.
Circulation: Arrhythmia and Electrophysiology. 2018;11:e005913
- Luke A. MacQueen, Sean P. Sheehy, Christophe O. Chantre, John F. Zimmerman, Francesco S. Pasqualini, Xujie Liu, Josue A. Goss, Patrick H. Campbell, Grant M. Gonzalez, Sung-Jin Park, Andrew K. Capulli, John P. Ferrier, T. Fettah Kosar, L. Mahadevan, William T. Pu and Kevin Kit Parker
A tissue-engineered scale model of the heart ventricle.
Nature Biomedical Engineering (2018). Published: 23 July 2018
- Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T. Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, and Igor R. Efimov
Multiparametric slice culture platform for the investigation of human cardiac tissue physiology.
Prog Biophys Mol Biol. 2018 Jun 27. pii: S0079-6107(18)30012-9.
- Alexander S. Teplenin, Hans Dierckx, Antoine A. F. de Vries, Daniël A. Pijnappels, and Alexander V. Panfilov
Paradoxical Onset of Arrhythmic Waves from Depolarized Areas in Cardiac Tissue Due to Curvature-Dependent Instability.
- Taylor Howard, Amara Greer-Short, Tony Satroplus, Nehal Patel, Drew Nassal, Peter J. Mohler, and Thomas J. Hund
CaMKII-dependent late Na+ current increases electrical dispersion and arrhythmia in ischemia-reperfusion.
Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H794-H801.
- Ying Zhang, Lei Jiao, Lihua Sun, Yanru Li, Yuqiu Gao, Chaoqian Xu, Yingchun Shao, Mengmeng Li, Chunyan Li, Yanjie Lu, Zhenwei Pan, Lina Xuan, Yiyuan Zhang, Qingqi Li, Rui Yang, Yuting Zhuang, Yong Zhang and Baofeng Yang
LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction.
- Samantha D. Francis Stuart, Lianguo Wang, William R. Woodard, G. Andre Ng, Beth A. Habecker and Crystal M. Ripplinger
Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.
- Diana C. Parrish, Samantha D. Francis Stuart, Antoinette Olivas, Lianguo Wang, Anders Nykjaer, Crystal M. Ripplinger, and Beth A. Habecker
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility.
Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H415-H423.
- Ronald A.Li, Wendy Keung, Timothy J. Cashman, Peter C. Backeris, Bryce V.Johnson, Evan S.Bardot, Andy O.T. Wong, Patrick K.W. Chan, Camie W.Y. Chan, Kevin D. Costa
Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.
- Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, Samuel C. Dudley Jr.
HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.
- Qiongling Wang, Ann P. Quick, Shuyi Cao, Julia Reynolds, David Y. Chiang, David Beavers, Na Li, Guoliang Wang, George G. Rodney, Mark E. Anderson, Xander H.T. Wehrens.
Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy.
- Jum-Suk Ko, Shuai Guo, Jonathan Hassel, Patricia Celestino-Soper, Ty C Lynnes, James E Tisdale, James J Zheng, Stanley E Taylor, Tatiana Foroud, Michael D Murray, Richard J Kovacs, Xiaochun Li, Shien-Fong Lin, Zhenhui Chen, Matteo Vatta, Peng-Sheng Chen, and Michael Rubart
Ondansetron Blocks Wildtype and p.F503L Variant Small Conductance Calcium Activated Potassium Channels.
- Wilhelm Roell, Alexandra M. Klein, Martin Breitbach, Torsten S. Becker, Ashish Parikh, Jane Lee, Katrin Zimmermann, Shaun Reining, Beth Gabris, Annika Ottersbach, Robert Doran, Britta Engelbrecht, Miriam Schiffer, Kenichi Kimura, Patricia Freitag, Esther Carls, Caroline Geisen, Georg D. Duerr, Philipp Sasse, Armin Welz, Alexander Pfeifer, Guy Salama, Michael Kotlikoff & Bernd K. Fleischmann
Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling.
- Daisuke Sasaki, Katsuhisa Matsuura, Hiroyoshi Seta, Yuji Haraguchi, Teruo Okano, Tatsuya Shimizu
Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue.
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