Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun ZhuProf, Sharon Gerecht, Gordon Tomaselli and Leslie Tung  

Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy using Plakophilin-2 Mutant Myocytes.

Tissue Eng Part A. 2018 Dec 6.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 

Zhen Wang, Lianguo Wang, Srinivas Tapa, Kent E. Pinkerton, Chao-Yin Chen and Crystal M. Ripplinger  

Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model.

Environmental Health Perspectives. 126(12) December 2018
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye

Adam Connolly, Allen Kelly, Fernando O. Campos, Rachel Myles, Godfrey Smith and Martin J. Bishop  

Ventricular Endocardial Tissue Geometry Affects Stimulus Threshold and Effective Refractory Period.

Biophys J. 2018 Dec 18;115(12):2486-2498.
MiCAM05 Voltage Sensitive Dye 

Kedar K. Aras, Ndeye Rokhaya Faye, Brianna Cathey and Igor R. Efimov  

Critical Volume of Human Myocardium Necessary to Maintain Ventricular Fibrillation.

Circ Arrhythm Electrophysiol. 2018 Nov;11(11):e006692.
MiCAM05 Voltage Sensitive Dye 

Rupamanjari Majumder, Iolanda Feola, Alexander S Teplenin, Antoine AF de Vries, Alexander V Panfilov and Daniel A Pijnappels  

Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system.

Elife. 2018 Sep 27;7. pii: e41076.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 

Virginie Dubes, David Benoist, François Roubertie, Stephen H. Gilbert, Marion Constantin, Sabine Charron, Delphine Elbes, Delphine Vieillot, Bruno Quesson, Hubert Cochet, Michel Haïssaguerre, Caroline Rooryck, Pierre Bordachar, Jean-Benoit Thambo, and Olivier Bernus  

Arrhythmogenic Remodeling of the Left Ventricle in a Porcine Model of Repaired Tetralogy of Fallot.

Circ Arrhythm Electrophysiol. 2018;11:e006059.
MiCAM ULTIMA Dual Camera System Voltage Sensitive Dye 

Yong Zhang, Lihua Sun, Lina Xuan, Zhenwei Pan, Xueling Hu, Hongyu Liu, Yunlong Bai, Lei Jiao, Zhange Li, Lina Cui, Xiaoxue Wang, Siqi Wang, Tingting Yu, Bingbing Feng, Ying Guo, Zonghong Liu, Weixin Meng, Hequn Ren, Jiyuan Zhu, Xuyun Zhao, Chao Yang, Ying Zhang, Chaoqian Xu, Zhiguo Wang, Yanjie Lu, Hongli Shan, and Baofeng Yang  

Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling.

Nat Commun. 2018 Oct 9;9(1):4176.
MiCAM05 Isolated Heart Voltage Sensitive Dye 

Jae Hyung Cho, Peter J. Kilfoil, Rui Zhang, Ryan E. Solymani, Catherine Bresee, Elliot M. Kang, Kristin Luther, Russell G. Rogers, Geoffrey de Couto, Joshua I. Goldhaber, Eduardo Marbán, and Eugenio Cingolani  

Reverse electrical remodeling in rats with heart failure and preserved ejection fraction.

JCI Insight. 2018;3(19):e121123.
MiCAM05 Isolated Heart Voltage Sensitive Dye 

Paul D. Pang, Katherina M. Alsina, Shuyi Cao, Amrita B. Koushik, Xander H.T. Wehrens and Thomas A. Cooper  

CRISPR‐Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.

J Am Heart Assoc. 2018;7:e010393.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Aida Olivan-Viguera, Angel Luis Garcia-Otin, Javier Lozano-Gerona, Edgar Abarca-Lachen, Ana J. Garcia-Malinis, Kirk L. Hamilton, Yolanda Gilaberte, Esther Pueyo, and Ralf Köhler  

Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

PLoS One. 2018 Jan 2;13(1):e0190307.
MiCAM05 Cultured Cell Calcium Sensitive Dye

Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, and Samuel C. Dudley Jr.  

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Heart Rhythm. 2018 Jul;15(7):1072-1080.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Marine E. Martinez, Richard D. Walton, Jason D. Bayer, Michel Haïssaguerre, Edward J. Vigmond, Mélèze Hocini and Olivier Bernus  

Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium.

Front Physiol. 2018 Jun 14;9:718.
MiCAM ULTIMA Voltage Sensitive Dye 

Taro Tenma, Hirofumi Mitsuyama, Masaya Watanabe, Naoya Kakutani, Yutaro Otsuka, Kazuya Mizukami, Rui Kamada, Masayuki Takahashi, Shingo Takada, Hisataka Sabe, Hiroyuki Tsutsui, and Hisashi Yokoshiki  

Small-conductance Ca2+-activated K+ channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy.

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H262-H272.
MiCAM02-HR Isolated Heart Voltage Sensitive Dye 

Dolkun Rahmutula, Hao Zhang, Emily E Wilson and Jeffrey E Olgin  

Absence of NPR-C Attenuates TGF-ß1 Induced Selective Atrial Fibrosis and Atrial Fibrillation.

Cardiovasc Res. 2018 Sep 18.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Daoyuan Si, Mohammed Ali Azam, Patrick F.H. Lai, Nima Zamiri, Galina Kichigina, John Asta, Stéphane Massé, Mahmoud M. Bokhari, Andreu Porta‐Sánchez, Christopher Labos, Huan Sun, Ping Yang and Kaumaraswamy Nanthakumar  

Essential Role of RyR2 Phosphorylation in the Effect of Azumolene on Ventricular Arrhythmia Vulnerability in a Rabbit Heart Model.

J Cardiovasc Electrophysiol. 2018 Sep 11.
MiCAM ULTIMA Isolated Heart Calcium Sensitive Dye

Rebecca Vicente Steijn, David Sedmera, Nico A. Blom, Monique Jongbloed, Alena Kvasilova, and Ondrej Nanka  

Apoptosis and epicardial contributions act as complementary factors in remodeling of the atrioventricular canal myocardium and atrioventricular conduction patterns in the embryonic chick heart.

Dev Dyn. 2018 Sep;247(9):1033-1042.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Yen-Ling Sung, Chih-En Wu, Jhen-Yang Syu,Terry B.J.Kuo, Jai-YiLi, Chieh-Wen Chen, Ching-Hui Weng, Wei-Hsuan Hsu, Shih-Ann Chen, Yu-Feng Hu and Shien-Fong Lin  

Effects of long-term exercise on arrhythmogenesis in aged hypertensive rats.

Comput Biol Med. 2018 Aug 16. pii: S0010-4825(18)30236-1.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Richard D. Walton, Ali Pashaei, Marine E. Martinez, Marion Constantin, Josselin Duchateau, Laura Bear, Caroline Cros, Caroline Pascarel-Auclerc, Yunbo Guo, David Benoist, Virginie Dubes, Ndeye Rokhaya Faye, Sebastien Chaigne, Sebastien Dupuis, Dominique Détaille, Line Pourtau, Philippe Pasdois, Fabien Brette, Julien Rogier, Louis Labrousse, Mélèze Hocini, Edward J. Vigmond, Michel Haïssaguerre and Olivier Bernus  

Compartmentalized Structure of the Moderator Band Provides a Unique Substrate for Macroreentrant Ventricular Tachycardia.

Circulation: Arrhythmia and Electrophysiology. 2018;11:e005913
MiCAM ULTIMA Voltage Sensitive Dye 

Luke A. MacQueen, Sean P. Sheehy, Christophe O. Chantre, John F. Zimmerman, Francesco S. Pasqualini, Xujie Liu, Josue A. Goss, Patrick H. Campbell, Grant M. Gonzalez, Sung-Jin Park, Andrew K. Capulli, John P. Ferrier, T. Fettah Kosar, L. Mahadevan, William T. Pu and Kevin Kit Parker   

A tissue-engineered scale model of the heart ventricle.

Nature Biomedical Engineering (2018). Published: 23 July 2018
MiCAM ULTIMA Calcium Sensitive Dye

Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T. Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, and Igor R. Efimov  

Multiparametric slice culture platform for the investigation of human cardiac tissue physiology.

Prog Biophys Mol Biol. 2018 Jun 27. pii: S0079-6107(18)30012-9.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 

Alexander S. Teplenin, Hans Dierckx, Antoine A. F. de Vries, Daniël A. Pijnappels, and Alexander V. Panfilov  

Paradoxical Onset of Arrhythmic Waves from Depolarized Areas in Cardiac Tissue Due to Curvature-Dependent Instability.

Phys Rev X. 2018 Jun 26; 8(2): 021077.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 

Taylor Howard, Amara Greer-Short, Tony Satroplus, Nehal Patel, Drew Nassal, Peter J. Mohler, and Thomas J. Hund  

CaMKII-dependent late Na+ current increases electrical dispersion and arrhythmia in ischemia-reperfusion.

Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H794-H801.
MiCAM05 Isolated Heart Voltage Sensitive Dye 

Ying Zhang, Lei Jiao, Lihua Sun, Yanru Li, Yuqiu Gao, Chaoqian Xu, Yingchun Shao, Mengmeng Li, Chunyan Li, Yanjie Lu, Zhenwei Pan, Lina Xuan, Yiyuan Zhang, Qingqi Li, Rui Yang, Yuting Zhuang, Yong Zhang and Baofeng Yang  

LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction.

Circ Res. 2018 May 11; 122(10): 1354–1368.
MiCAM05 Isolated Heart Calcium Sensitive Dye

Samantha D. Francis Stuart, Lianguo Wang, William R. Woodard, G. Andre Ng, Beth A. Habecker and Crystal M. Ripplinger  

Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.

J Physiol. 2018 Jun 25.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye

Diana C. Parrish, Samantha D. Francis Stuart, Antoinette Olivas, Lianguo Wang, Anders Nykjaer, Crystal M. Ripplinger, and Beth A. Habecker  

Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility.

Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H415-H423.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye

Ronald A.Li, Wendy Keung, Timothy J. Cashman, Peter C. Backeris, Bryce V.Johnson, Evan S.Bardot, Andy O.T. Wong, Patrick K.W. Chan, Camie W.Y. Chan, Kevin D. Costa  

Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.

Biomaterials. 2018 May;163:116-127
MiCAM ULTIMA Voltage Sensitive Dye 

Anyu Zhou, An Xie, Tae Yun Kim, Hong Liu, Guangbin Shi, Gyeoung-Jin Kang, Ning Jiang, Man Liu, Euy-Myoung Jeong, Bum-Rak Choi, Samuel C. Dudley Jr.  

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Heart Rhythm. 2018 Feb 16.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Qiongling Wang, Ann P. Quick, Shuyi Cao, Julia Reynolds, David Y. Chiang, David Beavers, Na Li, Guoliang Wang, George G. Rodney, Mark E. Anderson, Xander H.T. Wehrens.  

Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy.

Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005682.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Jum-Suk Ko, Shuai Guo, Jonathan Hassel, Patricia Celestino-Soper, Ty C Lynnes, James E Tisdale, James J Zheng, Stanley E Taylor, Tatiana Foroud, Michael D Murray, Richard J Kovacs, Xiaochun Li, Shien-Fong Lin, Zhenhui Chen, Matteo Vatta, Peng-Sheng Chen, and Michael Rubart  

Ondansetron Blocks Wildtype and p.F503L Variant Small Conductance Calcium Activated Potassium Channels.

Am J Physiol Heart Circ Physiol. 2018 Apr 20.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Wilhelm Roell, Alexandra M. Klein, Martin Breitbach, Torsten S. Becker, Ashish Parikh, Jane Lee, Katrin Zimmermann, Shaun Reining, Beth Gabris, Annika Ottersbach, Robert Doran, Britta Engelbrecht, Miriam Schiffer, Kenichi Kimura, Patricia Freitag, Esther Carls, Caroline Geisen, Georg D. Duerr, Philipp Sasse, Armin Welz, Alexander Pfeifer, Guy Salama, Michael Kotlikoff & Bernd K. Fleischmann  

Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling.

Sci Rep. 2018 May 8;8(1):7145.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 

Daisuke Sasaki, Katsuhisa Matsuura, Hiroyoshi Seta, Yuji Haraguchi, Teruo Okano, Tatsuya Shimizu  

Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue.

PLoS One. 2018 May 23;13(5):e0198026.
MiCAM ULTIMA Cultured Cell Calcium Sensitive Dye