膜電位感受性色素、カルシウム色素で染色された培養心筋細胞を使用した論文の一覧です。
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| 論文情報 | ｻﾝﾌﾟﾙ | 色素 | 使用 機器 |
|---|---|---|---|
| NaV1.5 knockout in iPSCs: a novel approach to study NaV1.5 variants in a human cardiomyocyte environment. Marion Pierre, Mohammed Djemai, Hugo Poulin, and Mohamed Chahine Sci Rep. 2021; 11: 17168. | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | VSD (Di-4-ANEPPS) CaSD (Rhod-2 AM) | MiCAM03 |
| High-Throughput Drug Screening System Based on Human Induced Pluripotent Stem Cell-Derived Atrial Myocytes ∼ A Novel Platform to Detect Cardiac Toxicity for Atrial Arrhythmias. Yayoi Honda, Jun Li, Aya Hino, Shinji Tsujimoto, and Jong-Kook Lee Front Pharmacol. 2021 Aug 3;12:680618. | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | VSD (FluoVolt) | MiCAM02 |
| Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC. Robert N. Hawthorne, Adriana Blazeski, Justin Lowenthal, Suraj Kannan, Roald Teuben, Deborah DiSilvestre, Justin Morrissette-McAlmon, Jeffrey E. Saffitz, Kenneth R. Boheler, Cynthia A. James, Stephen P. Chelko, Gordon Tomaselli and Leslie Tung J. Clin. Med. 2021, 10(14), 3061; | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | VSD (Di-4-ANEPPS) CaSD (Rhod-2 AM) | MiCAM ULTIMA |
| A 3-D Human Model of Complex Cardiac Arrhythmias. Kenneth Williams, Timothy Liang, Stéphane Massé, Safwat Khan, Rupal Hatkar, Gordon Keller, Kumaraswamy Nanthakumar, Sara S. Nunes Acta Biomaterialia Available online 10 March 2021 | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | CaSD | MiCAM ULTIMA |
| Human iPSC engineered cardiac tissue platform faithfully models important cardiac physiology. Willem J. de Lange, Emily T. Farrell, Caroline R. Kreitzer, Derek R. Jacobs, Di Lang, Alexey V. Glukhov, and J. Carter Ralphe Am J Physiol Heart Circ Physiol. 2021 Feb 19. | Human induced pluripotent stem cells (hiPSC-CM) | CaSD | MiCAM ULTIMA |
| Myocardial repair of bioengineered cardiac patches with decellularized placental scaffold and human-induced pluripotent stem cells in a rat model of myocardial infarction. Yu Jiang, Si-Jia Sun, Zhe Zhen, Rui Wei, Nannan Zhang, Song-Yan Liao & Hung-Fat Tse Stem Cell Res Ther 12, 13 (2021). | Bioengineered cardiac patch (human-induced pluripotent stem cell-derived cardiomyocytes: hiPSC-CMs) | CaSD (Fura-2 AM) | MiCAM ULTIMA |
| iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities. Hugo Poulin, Aurélie Mercier, Mohammed Djemai, Valérie Pouliot, Isabelle Deschenes, Mohamed Boutjdir, Jack Puymirat & Mohamed Chahine Scientific Reports volume 11, Article number: 2500 (2021) | Induced pluripotent stem-derived cardiomyocytes (iPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM03 |
| Scaffold-Mediated Developmental Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Are Preserved After External Support Removal. Jun Li, Jong-Kook Lee, Keiko Miwa, Yuki Kuramoto, Kiyoshi Masuyama, Hideki Yasutake, Satoki Tomoyama, Hiroyuki Nakanishi, and Yasushi Sakata Front Cell Dev Biol. 2021; 9: 591754. | Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs) | VSD (FluoVolt) | MiCAM02 |
| Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues. Andy On-Tik Wong, Bimal Gurung, Wing Sum Wong, Suet Yee Mak, Wan Wai Tse, Chloe M. Li, Deborah K. Lieu, Kevin D. Costa, Ronald A. Li, and Roger J. Hajjar J Mol Cell Cardiol. 2021 Apr; 153: 106–110. | Human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | ? | MiCAM03 |
| Local hyperactivation of L-type Ca2+ channels increases spontaneous Ca2+ release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats. Roman Y. Medvedev, Jose L. Sanchez-Alonso, Catherine A. Mansfield, Aleksandra Judina, Alice J. Francis, Christina Pagiatakis, Natalia Trayanova, Alexey V. Glukhov, Michele Miragoli, Giuseppe Faggian & Julia Gorelik Scientific Reports volume 11, Article number: 4840 (2021) | Isolated myocytes | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium. Cassady E. Rupert, Tae Yun Kim, Bum-Rak Choi, and Kareen L. K. Coulombe Stem Cells Int. 2020; 2020: 9363809. | Engineered cardiac tissues | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity. Jessica M. Miller, Moustafa H. Meki, Qinghui Oua, Sharon A. George, Anna Gams, Riham R.E. Abouleisa, Xian-Liang Tang, Brooke M. Ahern, Guruprasad A. Giridharan, Ayman El-Baz, Bradford G. Hill, Jonathan Satin, Daniel J.Conklin, Javid Moslehi, Roberto Bolli, Alexandre J.S. Ribeiro, Igor R. Efimov, Tamer M.A. Mohamed Toxicology and Applied Pharmacology, Volume 406, 2020,115213 | Cultured heart slice | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts. B. N. Napiwocki, D. Lang, A. Stempien, J. Zhang, R. Vaidyanathan, J. C. Makielski, L. L. Eckhardt, A. V. Glukhov, T. J. Kamp, W. C. Crone Biotechnology and Bioengineering. 2021; 118: 442– 452. | Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) | CaSD (Rhod-2 AM) | MiCAM ULTIMA |
| The proarrhythmic features of pathological cardiac hypertrophy in neonatal rat ventricular cardiomyocyte cultures Zeinab Neshati, Martin J Schalij, Antoine A F de Vries J Appl Physiol (1985). 2020 Mar 1;128(3):545-553. | Neonatal rat ventricular cardiomyocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Adrenoceptor Responses in Human Embryonic Stem Cell-Derived Cardiomyocytes: a Special Focus on Electrophysiological Property. Weiwei Jiang, Xingjian Hu, Fei Li, Geng Li, Yin Wang J Pharmacol Exp Ther. 2020 Jun;373(3):429-437. | Human embryonic stem cell‐derived cardiomyocytes (hESC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Single‐Cell Transcriptomics of Engineered Cardiac Tissues From Patient‐Specific Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Abnormal Developmental Trajectory and Intrinsic Contractile Defects in Hypoplastic Right Heart Syndrome. Yin‐Yu Lam, Wendy Keung, Chun‐Ho Chan, Lin Geng, Nicodemus Wong, David Brenière‐Letuffe, Ronald A. Li and Yiu‐Fai Cheung J Am Heart Assoc. 2020 Oct 20; 9(20): e016528. | Human cardiac anisotropic sheet | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients. Andy On-Tik Wong, Nicodemus Wong, Lin Geng, Maggie Zi-ying Chow, Eugene K. Lee, Hongkai Wu, Michelle Khine, Chi-Wing Kong, Kevin D. Costa, Wendy Keung, Yiu-Fai Cheung, and Ronald A. Li Front Physiol. 2020; 11: 165. | Human ventricular cardiac anisotropic sheet preparations | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Functional Properties of Engineered Heart Slices Incorporating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Adriana Blazeski, Justin Lowenthal, Renjun Zhu, Jourdan Ewoldt, Kenneth R. Boheler, and Leslie Tung Theranostics. 2019; 9(24): 7222–7238. | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variation. Sarkawt Hamad, Daniel Derichsweiler, Symeon Papadopoulos, Filomain Nguemo, Tomo Šarić, Agapios Sachinidis, Konrad Brockmeier, Jürgen Hescheler, Bastiaan J Boukens, and Kurt Pfannkuche Theranostics. 2019; 9(24): 7222–7238. | Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes. Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun Zhu, Sharon Gerecht, Gordon Tomaselli, Leslie Tung Tissue Eng Part A. 2019 May;25(9-10):725-735. | Engineered heart slices | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Correlation between frataxin expression and contractility revealed by in vitro Friedreich's ataxia cardiac tissue models engineered from human pluripotent stem cells. Andy On-Tik Wong, Gabriel Wong, Michael Shen, Maggie Zi-Ying Chow, Wan Wai Tse, Bimal Gurung, Suet Yee Mak, Deborah K Lieu, Kevin D Costa, Camie W Chan, Alain Martelli, Joseph F Nabhan, Ronald A Li Stem Cell Res Ther. 2019 Jul 8;10(1):203. | Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Contribution of potassium channels to action potential repolarization of human embryonic stem cell-derived cardiomyocytes. Yin Wang, Renjun Zhu, Leslie Tung Br J Pharmacol. 2019 Aug;176(15):2780-2794. | Human embryonic stem cell‐derived cardiomyocytes (hESC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Enhancement of human iPSC-derived cardiomyocyte maturation by chemical conditioning in a 3D environment. Chen Yu Huang, Rebeca Peres Moreno Maia-Joca, Chin Siang Ong, Ijala Wilson, Deborah DiSilvestre, Gordon F Tomaselli, Daniel H Reich J Mol Cell Cardiol. 2020 Jan;138:1-11. | Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An In vitro Disease Model of Atrial Arrhythmias. Hiroyuki Nakanishi, Jong-Kook Lee, Keiko Miwa, Kiyoshi Masuyama, Hideki Yasutake, Jun Li, Satoki Tomoyama, Yayoi Honda, Jiro Deguchi, Shinji Tsujimoto, Kyoko Hidaka, Shigeru Miyagawa, Yoshiki Sawa, Issei Komuro, Yasushi Sakata Front Physiol. 2019 Jun 27;10:818. | Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs) | VSD (FluoVolt) | MiCAM02 |
| Multiparametric slice culture platform for the investigation of human cardiac tissue physiology. Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, Igor R Efimov Prog Biophys Mol Biol. 2019 Jul;144:139-150. | Cultured murine atria and human slices | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing. Anna M. D. Végh, A. Dénise Den Haan, Lucía Cócera Ortega, Arie O. Verkerk, Joost P. G. Sluijter, Diane Bakker, Shirley Van Amersfoorth, Toon A. B. Van Veen, Mischa Klerk, Jurgen Seppen, Jacques M. T. De Bakker, Vincent M. Christoffels, Dirk Geerts, Marie José T. H. Goumans, Hanno L. Tan and Gerard J. J. Boink Molecules. 2019 Jan 5;24(1). pii: E181. | Organ explant cultures | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy using Plakophilin-2 Mutant Myocytes. Adriana Blazeski, Justin Lowenthal, Yin Wang, Roald Teuben, Renjun ZhuProf, Sharon Gerecht, Gordon Tomaselli and Leslie Tung Tissue Eng Part A. 2018 Dec 6. | Engineered heart slices | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system. Rupamanjari Majumder, Iolanda Feola, Alexander S Teplenin, Antoine AF de Vries, Alexander V Panfilov and Daniel A Pijnappels Elife. 2018 Sep 27;7. pii: e41076. | Neonatal rat atrial cardiomyocytes | VSD (Di-4-ANBDQBS) | MiCAM ULTIMA |
| A tissue-engineered scale model of the heart ventricle. Luke A. MacQueen, Sean P. Sheehy, Christophe O. Chantre, John F. Zimmerman, Francesco S. Pasqualini, Xujie Liu, Josue A. Goss, Patrick H. Campbell, Grant M. Gonzalez, Sung-Jin Park, Andrew K. Capulli, John P. Ferrier, T. Fettah Kosar, L. Mahadevan, William T. Pu and Kevin Kit Parker Nature Biomedical Engineering (2018). Published: 23 July 2018 | Neonatal rat ventricular myocytes | CaSD (Rhod-2) | MiCAM ULTIMA |
| Multiparametric slice culture platform for the investigation of human cardiac tissue physiology. Yun Qiao, Quan Dong, Baichen Li, Sofian Obaid, Christian Miccile, Rose T. Yin, Trisha Talapatra, Zexu Lin, Sihui Li, Zhenyu Li, and Igor R. Efimov Prog Biophys Mol Biol. 2018 Jun 27. pii: S0079-6107(18)30012-9. | Cultured mouse atrial tissue and human cardiac slices | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Paradoxical Onset of Arrhythmic Waves from Depolarized Areas in Cardiac Tissue Due to Curvature-Dependent Instability. Alexander S. Teplenin, Hans Dierckx, Antoine A. F. de Vries, Daniël A. Pijnappels, and Alexander V. Panfilov Phys Rev X. 2018 Jun 26; 8(2): 021077. | Neonatal rat ventricular myocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Ronald A.Li, Wendy Keung, Timothy J. Cashman, Peter C. Backeris, Bryce V.Johnson, Evan S.Bardot, Andy O.T. Wong, Patrick K.W. Chan, Camie W.Y. Chan, Kevin D. Costa Biomaterials. 2018 May;163:116-127 | Human ventricle-like cardiac organoid chamber | VSD (Di-8-ANEPPS) CaSD (X-rhod-1 AM) | MiCAM ULTIMA |
| Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue. Daisuke Sasaki, Katsuhisa Matsuura, Hiroyoshi Seta, Yuji Haraguchi, Teruo Okano, Tatsuya Shimizu PLoS One. 2018 May 23;13(5):e0198026. | Human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs) | CaSD (Fluo-8) | MiCAM ULTIMA |
| Resolving Myocardial Activation With Novel Omnipolar Electrograms. Stéphane Massé, Karl Magtibay, Nicholas Jackson, John Asta, Marjan Kusha, Boyang Zhang, Ram Balachandran, Milica Radisic, D. Curtis Deno, and Kumaraswamy Nanthakumar Circ Arrhythm Electrophysiol. 2016 Jul;9(7):e004107. doi: 10.1161/CIRCEP.116.004107. | Monolayers | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Variability of Action Potentials Within and Among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells. Renjun Zhu, Michal A. Millrod, Elias T. Zambidis, and Leslie Tung Sci Rep. 2016 Jan 5;6:18544. doi: 10.1038/srep18544. | Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing. Johan U. Lind, Travis A. Busbee, Alexander D. Valentine, Francesco S. Pasqualini, Hongyan Yuan, Moran Yadid, Sung-Jin Park, Arda Kotikian, Alexander P. Nesmith, Patrick H. Campbell, Joost J. Vlassak, Jennifer A. Lewis and Kevin K. Parker Nat Mater. 2016 Oct 24. doi: 10.1038/nmat4782. [Epub ahead of print] | Neonatal rat ventricular myocytes | VSD (RH-237) | MiCAM ULTIMA |
| Optogenetic Engineering of Atrial Cardiomyocytes. Iolanda Feola, Alexander Teplenin, Antoine A. F. de Vries, Daniël A. Pijnappels Methods Mol Biol. 2016;1408:319-31. doi: 10.1007/978-1-4939-3512-3_22. | Atrial cardiomyocytes (aCMCs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity. Angie M. Y. Shum, Hui Che, Andy On-Tik Wong, Chenzi Zhang, Hongkai Wu, Camie W. Y. Chan, Kevin Costa, Michelle Khine, Chi-Wing Kong, Ronald A. Li Adv Mater. 2016 Nov 2. doi: 10.1002/adma.201602448. [Epub ahead of print] | Human ventricular cardiac anisotropic sheet (hvCAS) | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Islands of spatially discordant APD alternans underlie arrhythmogenesis by promoting electrotonic dyssynchrony in models of fibrotic rat ventricular myocardium Rupamanjari Majumder, Marc C. Engels, Antoine A. F. de Vries, Alexander V. Panfilov, and Daniël A. Pijnappels Sci Rep. 2016; 6: 24334. Published online 2016 Apr 13. doi: 10.1038/srep24334 | Monolayers | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Electroactive polyurethane/siloxane derived from castor oil as a versatile cardiac patch, Part II: HL-1 cytocompatibility and electrical characterizations. Nafiseh Baheiraei, Reza Gharibi, Hamid Yeganeh, Michele Miragoli, Nicolò Salvarani, Elisa Di Pasquale and Gianluigi Condorelli J Biomed Mater Res A. 2016 Jan 28. doi: 10.1002/jbm.a.35669. [Epub ahead of print] | HL-1 monolayers | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts. Francisca Schultz, Alveera Hasan, Anita Alvarez-Laviada, Michele Miragoli, Navneet Bhogal, Sarah Wells, Claire Poulet, Jenny Chambers, Catherine Williamson and Julia Gorelik Prog Biophys Mol Biol. 2016 Jan 8. pii: S0079-6107(16)00005-5. doi: 10.1016/j.pbiomolbio.2016.01.003. [Epub ahead of print] | Isolated cardiomyocytes | CaSD (Fluo-4 AM) VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes. Michele Miragoli, Jose L. Sanchez-Alonso, Anamika Bhargava, Peter T. Wright, Markus Sikkel, Sophie Schobesberger, Ivan Diakonov, Pavel Novak, Alessandra Castaldi, Paola Cattaneo, Alexander R. Lyon, Max J. Lab, Julia Gorelik Cell Rep. 2016 Jan 5;14(1):140-51. doi: 10.1016/j.celrep.2015.12.014. Epub 2015 Dec 24. | Isolated cardiomyocytes | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy. Bo Lin, Yang Li, Lu Han, Aaron D. Kaplan, Ying Ao, Spandan Kalra, Glenna C. L. Bett, Randall L. Rasmusson, Chris Denning and Lei Yang Dis Model Mech. 2015 May;8(5):457-66. doi: 10.1242/dmm.019505. Epub 2015 Mar 19. | Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) | CaSD (Rhod-2 AM) | MiCAM ULTIMA |
| Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes. Alexey V. Glukhov, Marina Balycheva, Jose L. Sanchez-Alonso, Zeki Ilkan, Anita Alvarez-Laviada, Navneet Bhogal, Ivan Diakonov, Sophie Schobesberger, Markus B. Sikkel, Anamika Bhargava, Giuseppe Faggian, Prakash P. Punjabi, Steven R. Houser and Julia Gorelik Circulation. 2015 Oct 8. pii: CIRCULATIONAHA.115.018131. [Epub ahead of print] | Human atrial myocytes | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Gaopeng Chen, Sen Li, Ioannis Karakikes, Lihuan Ren, Maggie Zi-Ying Chow, Anant Chopra, Wendy Keung, Bin Yan, Camie WY Chan, Kevin D. Costa, Chi-Wing Kong, Roger J. Hajjar, Christopher S. Chen and Ronald A. Li Circ Arrhythm Electrophysiol. 2015 Feb;8(1):193-202. doi: 10.1161/CIRCEP.114.002049. Epub 2014 Dec 10. | hESC/iPSC-vCMs | CaSD (X-Rhod-1 AM) | MiCAM ULTIMA |
| Combining TGF-β signal inhibition and connexin43 silencing for iPSC induction from mouse cardiomyocytes Ping Dai, Yoshinori Harada, Hitoshi Miyachi, Hideo Tanaka, Satsuki Kitano, Tetsuya Adachi, Tomoyuki Suzuki, Hitoshi Hino and Tetsuro Takamatsu Sci Rep. 2014; 4: 7323. | Cardiomyocytes derived from siPSCs | CaSD (Fluo-4 AM) | MiCAM02 |
| Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes. Brian O. Bingen, Marc C. Engels, Martin J. Schalij, Wanchana Jangsangthong, Zeinab Neshati, Iolanda Feola, Dirk L. Ypey, Saïd F.A. Askar, Alexander V. Panfilov, Daniël A. Pijnappels and Antoine A.F. de Vries Cardiovasc Res. 2014 Jul 31. pii: cvu179. [Epub ahead of print] | Neonatal rat atrial cardiomyocyte monolayers | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. C. Ian Spencer, Shiro Baba, Kenta Nakamura, Ethan A. Hua, Marie A.F. Sears, Chi-cheng Fu, Jianhua Zhang, Sadguna Balijepalli, Kiichiro Tomoda, Yohei Hayashi, Paweena Lizarraga, Julianne Wojciak, Melvin M. Scheinman, Katriina Aalto-Setälä, Jonathan C. Makielski, Craig T. January, Kevin E. Healy, Timothy J. Kamp, Shinya Yamanaka, Bruce R. Conklinemail Stem Cell Reports. 2014 Aug 12;3(2):269-281. | Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) | CaSD (Fluo-4 AM) | MiCAM02 |
| Quality metrics for stem cell-derived cardiac myocytes. Sean P. Sheehy, Francesco Pasqualini, Anna Grosberg, Sung Jin Park, Yvonne Aratyn-Schaus and Kevin Kit Parker Stem Cell Reports. 2014 Mar 6;2(3):282-94. doi: 10.1016/j.stemcr.2014.01.015. eCollection 2014. | Neonatal mouse ventricular cardiomyocytes | VSD (RH-237) | MiCAM ULTIMA |
| Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State. Weining Bian, Nima Badie, Herman D. Himel IV and Nenad Bursac Biomaterials. 2014 Apr;35(12):3819-28. doi: 10.1016/j.biomaterials.2014.01.045. Epub 2014 Feb 6. | Neonatal rat ventricular cardiomyocytes | CaSD (Rhod-2) | MiCAM ULTIMA |
| Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias. Jiaxian Wang, Aaron Chen, Deborah K. Lieu, Ioannis Karakikes, Gaopeng Chen, Wendy Keung, Camie W. Chan, Roger J. Hajjar, Kevin D. Costa, Michelle Khine and Ronald A. Li Biomaterials. 2013 Nov;34(35):8878-86. doi: 10.1016/j.biomaterials.2013.07.039. Epub 2013 Aug 12. | Human pluripotent stem cell-derived ventricular cardiomyocytes (hPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State. Ji-Dong Fu, Nicole R. Stone, Lei Liu, C. Ian Spencer, Li Qian, Yohei Hayashi, Paul Delgado-Olguin, Sheng Ding, Benoit G. Bruneau and Deepak Srivastava Stem Cell Reports, Volume 1, Issue 3, 235-247, 22 August 2013 | Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) | CaSD (Fluo-4 AM) | MiCAM02 |
| CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia. Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G and Priori SG Cell Death Dis. 2013 Oct 10;4:e843. doi: 10.1038/cddis.2013.369. | iPSC-derived cardiac cells | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Repopulation of decellularized mouse heart with human induced pluripotent stem cell-derived cardiovascular progenitor cells. Tung-Ying Lu, Bo Lin, Jong Kim, Mara Sullivan, Kimimasa Tobita, Guy Salama and Lei Yang Nat Commun. 2013 Aug 14;4:2307. doi: 10.1038/ncomms3307. | Human induced pluripotent stem cell-derived cardiovascular progenitor cells | CaSD (Rhod-2) | MiCAM ULTIMA |
| Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Sara S Nunes, Jason W Miklas, Jie Liu, Roozbeh Aschar-Sobbi, Yun Xiao, Boyang Zhang, Jiahua Jiang, Stéphane Massé, Mark Gagliardi, Anne Hsieh, Nimalan Thavandiran, Michael A Laflamme, Kumaraswamy Nanthakumar, Gil J Gross, Peter H Backx, Gordon Keller and Milica Radisic Nat Methods. 2013 Aug;10(8):781-7. doi: 10.1038/nmeth.2524. Epub 2013 Jun 23. | Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Fibroblast KATP Currents Modulate Myocyte Electrophysiology in Infarcted Hearts. Najate Benamer, Carolina Vasquez, Vanessa M Mahoney, Maximilian J Steinhardt, William A Coetzee, and Gregory E Morley Am J Physiol Heart Circ Physiol. 2013 May;304(9):H1231-9. doi: 10.1152/ajpheart.00878.2012. Epub 2013 Feb 22. | Monolayer | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Oscillation in Cycle Length Induces Transient Discordant and Steady-State Concordant Alternans in the Heart. Seth H. Weinberg and Leslie Tung PLoS One. 2012;7(7):e40477. Epub 2012 Jul 5. | Monolayer | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| ILK Induces Cardiomyogenesis in the Human Heart. Alexandra Traister, Shabana Aafaqi, Stephane Masse, Xiaojing Dai, Mark Li, Aleksander Hinek, Kumaraswamy Nanthakumar, Gregory Hannigan and John G. Coles Med Image Anal. 2012 Feb;16(2):505-23. Epub 2011 Dec 6. | Human fetal cardiomyocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Functional Scaffold-Free 3D Cardiac Microtissues: a Novel Model for the Investigation of Heart Cells. Bethany R Desroches, Peng Zhang, Bum-Rak Choi, Michelle E King, Angel E Maldonado, Weiyan Li, Adam Rago, Gong-Xin Liu, Nandan Nath, Kathryn M Hartmann, Bryant Yang, Gideon Koren, Jeffrey R Morgan and Ulrike Mende Am J Physiol Heart Circ Physiol. 2012 Mar 16. [Epub ahead of print] | Neonatal rat cardiomyocytes | VSD (RH-237) | MiCAM ULTIMA |
| High-purity enrichment of functional cardiovascular cells from human iPS cells. Bo Lin, Jong Kim, Yanxin Li, Haiying Pan, Xonia Carvajal-Vergara, Guy Salama, Tao Cheng, Yong Li, Cecilia W. Lo and Lei Yang Cardiovasc Res. 2012 Aug 1;95(3):327-35. Epub 2012 Jun 6. | Human iPSC-derived cardiovascular cells | CaSD (Rhod-2) | MiCAM ULTIMA |
| Connexin43 silencing in myofibroblasts prevents arrhythmias in myocardial cultures: role of maximal diastolic potential. Saïd F. Askar, Brian O. Bingen, Jim Swildens, Dirk L. Ypey, Arnoud van der Laarse, Douwe E. Atsma, Katja Zeppenfeld, Martin J. Schalij, Antoine A. de Vries and Daniël A. Pijnappels Cardiovasc Res. 2012 Mar 1;93(3):434-44. Epub 2011 Dec 22. | Primary ventricular cardiomyocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. Aaron Chen, Deborah K. Lieu, Lauren Freschauf, Valerie Lew, Himanshu Sharma, Jiaxian Wang, Diep Nguyen, Ioannis Karakikes, Roger J. Hajjar, Ajay Gopinathan, Elliot Botvinick, Charless C. Fowlkes, Ronald A. Li and Michelle Khine Adv Mater. 2011 Dec 22;23(48):5785-91. doi: 10.1002/adma.201103463. Epub 2011 Nov 8. | Human embryonic stem cells-derived cardiomyocytes (hESC-CMs) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts. Arti A. Ramkisoensing, Daniël A. Pijnappels, Saïd F. A. Askar, Robert Passier, Jim Swildens, Marie José Goumans, Cindy I. Schutte, Antoine A. F. de Vries, Sicco Scherjon, Christine L. Mummery, Martin J. Schalij and Douwe E. Atsma PLoS One. 2011;6(9):e24164. Epub 2011 Sep 9. | Neonatal rat ventricular cardiomyocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Michele Miragoli, Siti H. Sheikh Abdul Kadir, Mary N. Sheppard, Nicoló Salvarani, Matilda Virta, Sarah Wells, Max J. Lab, Viacheslav O. Nikolaev, Alexey Moshkov, William M. Hague, Stephan Rohr, Catherine Williamson and Julia Gorelik Hepatology. 2011 Oct;54(4):1282-92. doi: 10.1002/hep.24492. Epub 2011 Aug 1. | Monolayer | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Antiproliferative treatment of myofibroblasts prevents arrhythmias in vitro by limiting myofibroblast-induced depolarization. Saïd F.A. Askar, Arti A. Ramkisoensing, Martin J. Schalij, Brian O. Bingen, Jim Swildens, Arnoud van der Laarse, Douwe E. Atsma, Antoine A.F. de Vries, Dirk L. Ypey and Daniël A. Pijnappels Cardiovasc Res. 2011 Feb 2. [Epub ahead of print] | Neonatal rat ventricular cardiomyocytes | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Enhanced fibroblast-myocyte interactions in response to cardiac injury. Carolina Vasquez, Poornima Mohandas, Karen L. Louie, Najate Benamer, Ashwini C. Bapat and Gregory E. Morley Circ Res. 2010 Oct 15;107(8):1011-20. Epub 2010 Aug 12. | Monolayer | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Masaki Ieda, Ji-Dong Fu, Paul Delgado-Olguin, Vasanth Vedantham, Yohei Hayashi, Benoit G. Bruneau and Deepak Srivastava Cell. 2010 Aug 6;142(3):375-86. | Cardiac fibroblast–derived induced cardiomyocytes | CaSD (Rhod-3) | MiCAM02 |
| Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M2 Receptors in Neonatal Rat Cardiomyocytes. Siti H. Sheikh Abdul Kadir, Michele Miragoli, Shadi Abu-Hayyeh, Alexey V. Moshkov, Qilian Xie, Verna Keitel, Viacheslav O. Nikolaev, Catherine Williamson and Julia Gorelik PLoS One. 2010; 5(3): e9689. | Ventricular neonatal rat myocyte | CaSD (Fluo-4 AM) | MiCAM ULTIMA |
| Engineered heart tissue: a novel tool to study the ischemic changes of the heart in vitro. Rajesh G. Katare, Motonori Ando, Yoshihiko Kakinuma and Takayuki Sato PLoS One. 2010 Feb 17;5(2):e9275. | Engineered heart tissue | VSD (Di-4-ANEPPS) | MiCAM02 |
| Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Hannah Song, Charles Yoon, Steven J. Kattman, Jana Dengler, Stéphane Massé, Thushaanthini Thavaratnam, Mena Gewarges, Kumaraswamy Nanthakumar, Michael Rubart, Gordon M. Keller, Milica Radisic and Peter W. Zandstra Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3329-34. | Engineered heart tissue | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Electrogram fractionation in murine HL-1 atrial monolayer model. Karthikeyan Umapathy, Stephane Masse, Karolina Kolodziejska, George D. Veenhuyzen, Vijay S. Chauhan, Mansoor Husain, Talha Farid, Eugene Downar, Elias Sevaptsidis and Kumaraswamy Nanthakumar Heart Rhythm. 2008 Jul;5(7):1029-35. | Monolayer (HL-1) | VSD (Di-4-ANEPPS) | MiCAM ULTIMA |
| Generation of reentrant arrhythmias by dominant-negative inhibition of connexin43 in rat cultured myocyte monolayers Takuo Nakagami, Hideo Tanaka, Ping Dai, Shien-Fong Lin, Takuji Tanabe, Hiroki Mani, Katsuji Fujiwara, Hiroaki Matsubara and Tetsuro Takamatsu Cardiovasc Res. 2008 Jul 1;79(1):70-9. Epub 2008 Mar 31. | Monolayer | CaSD (Fluo-4) | MiCAM02 |
| Myofibroblasts induce ectopic activity in cardiac tissue. Michele Miragoli, Nicolò Salvarani and Stephan Rohr Circ Res. 2007 Oct 12;101(8):755-8. | Monolayer | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| Dynamic changes of cardiac conduction during rapid pacing. Aleksandar A. Kondratyev, Julien G. C. Ponard, Adelina Munteanu, Stephan Rohr and Jan P. Kucera Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1796-1811. | Monolayer | VSD (Di-8-ANEPPS) | MiCAM ULTIMA |
| A new method for manufacturing cardiac cell sheets using fibrin-coated dishes and its electrophysiological studies by optical mapping. Yuji Itabashi, Shunichiro Miyoshi, Haruko Kawaguchi, Shinsuke Yuasa, Kojiro Tanimoto, Akira Furuta, Tatsuya Shimizu, Teruo Okano, Keiichi Fukuda and Satoshi Ogawa Artif Organs. 2005 Feb;29(2):95-103. | Myocardial cell sheets | VSD (Di-4-ANEPPS) | MiCAM01 |