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2011

David Sedmera

Function and form in the developing cardiovascular system.

Cardiovasc Res. 2011 Jul 15;91(2):252-9. doi: 10.1093/cvr/cvr062. Epub 2011 Mar 2.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Bo Lin, Jong Kim, Yanxin Li, Haiying Pan, Xonia Carvajal-Vergara, Guy Salama, Tao Cheng, Yong Li, Cecilia W. Lo and Lei Yang  

High-purity enrichment of functional cardiovascular cells from human iPS cells.

Cardiovasc Res. 2012 Aug 1;95(3):327-35. Epub 2012 Jun 6.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

O. Camara, M. Sermesant, P. Lamata, L. Wang,M. Pop, J. Relan, M. De Craene, H. Delingette, H. Liu, S. Niederer, A. Pashaei, G. Plank, D. Romero R. Sebastian, K.C.L. Wong, H. Zhang, N. Ayache, A.F. Frangi, P. Shi, N.P. Smith G.A. Wright  

Inter-model consistency and complementarity: Learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology.

Prog Biophys Mol Biol. 2011 Oct;107(1):122-33. Epub 2011 Jul 20.
MiCAM02-HR Isolated Heart Voltage Sensitive Dye

Saïd F. Askar, Brian O. Bingen, Jim Swildens, Dirk L. Ypey, Arnoud van der Laarse, Douwe E. Atsma, Katja Zeppenfeld, Martin J. Schalij, Antoine A. de Vries and Daniël A. Pijnappels

Connexin43 silencing in myofibroblasts prevents arrhythmias in myocardial cultures: role of maximal diastolic potential.

Cardiovasc Res. 2012 Mar 1;93(3):434-44. Epub 2011 Dec 22.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye

Aaron Chen, Deborah K. Lieu, Lauren Freschauf, Valerie Lew, Himanshu Sharma, Jiaxian Wang, Diep Nguyen, Ioannis Karakikes, Roger J. Hajjar, Ajay Gopinathan, Elliot Botvinick, Charless C. Fowlkes, Ronald A. Li and Michelle Khine

Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives.

Adv Mater. 2011 Dec 22;23(48):5785-91. doi: 10.1002/adma.201103463. Epub 2011 Nov 8.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye

Paulus Kirchhof, Eloi Marijond, Larissa Fabritza, Na Li, Wei Wang, Tiannan Wang, Kirsten Schulte, Juliane Hanstein, Jan S. Schulte, Mathis Vogel, Nathalie Mougenot, Sandra Laakmann, Lisa Fortmueller, Jens Eckstein, Sander Verheule, Sven Kaese, Ariane Staab, Stephanie Grote-Wessels, Ulrich Schotten, Ghassan Moubarak, Xander H.T. Wehrens, Wilhelm Schmitz, Stéphane Hatem, Frank Ulrich Müller.

Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice.

Int J Cardiol. 2011 Nov 15. [Epub ahead of print]
MiCAM ULTIMA Voltage Sensitive Dye

Stacey Rentschler, Brett S. Harris, Laura Kuznekoff, Rajan Jain, Lauren Manderfield, Min Min Lu, Gregory E. Morley, Vickas V. Patel and Jonathan A. Epstein  [Author’s HP]

Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.

J Clin Invest. 2011 Feb;121(2):525-33. doi: 10.1172/JCI44470. Epub 2011 Jan 25.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Lou Q, Fedorov VV, Glukhov AV, Moazami N, Fast VG, Efimov IR.

Transmural heterogeneity and remodeling of ventricular excitation-contraction coupling in human heart failure.

Circulation. 2011 May 3;123(17):1881-90. Epub 2011 Apr 18.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Di Lang, Valentin Petrov, Qing Lou, Grigory Osipov and Igor R. Efimov.

Spatiotemporal control of heart rate in a rabbit heart.

J Electrocardiol. 2011 Nov-Dec;44(6):626-34. Epub 2011 Sep 19.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Arti A. Ramkisoensing, Daniël A. Pijnappels, Saïd F. A. Askar, Robert Passier, Jim Swildens, Marie José Goumans, Cindy I. Schutte, Antoine A. F. de Vries, Sicco Scherjon, Christine L. Mummery, Martin J. Schalij and Douwe E. Atsma

Human Embryonic and Fetal Mesenchymal Stem Cells Differentiate toward Three Different Cardiac Lineages in Contrast to Their Adult Counterparts.

PLoS One. 2011;6(9):e24164. Epub 2011 Sep 9.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye

Remo BF, Qu J, Volpicelli FM, Giovannone S, Shin D, Lader J, Liu FY, Zhang J, Lent DS, Morley GE, Fishman GI.

Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias.

Circ Res. 2011 Jun 10;108(12):1459-66. Epub 2011 Apr 28.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Fedorov VV, Ambrosi CM, Kostecki G, Hucker WJ, Glukhov AV, Wuskell JP, Loew LM, Moazami N, Efimov IR.

Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts.

Circ Arrhythm Electrophysiol. 2011 Aug 1;4(4):515-25. Epub 2011 Jun 6.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Lang D, Glukhov AV, Efimova T, Efimov IR.

Role of Pyk2 in cardiac arrhythmogenesis.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H975-83. Epub 2011 Jun 10.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Miragoli M, Kadir SH, Sheppard MN, Salvarani N, Virta M, Wells S, Lab MJ, Nikolaev VO, Moshkov A, Hague WM, Rohr S, Williamson C, Gorelik J.

A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart.

Hepatology. 2011 Oct;54(4):1282-92. doi: 10.1002/hep.24492. Epub 2011 Aug 1.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye

Bernstein SA, Duggirala S, Floberg M, Elfvendal P, Kuznekoff LM, Lader JM, Vasquez C, Morley GE.

Spatiotemporal electrophysiological changes in a murine ablation model.

Europace. 2011 Oct;13(10):1494-500. Epub 2011 Jun 28.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Tsai CT, Wu CK, Chiang FT, Tseng CD, Lee JK, Yu CC, Wang YC, Lai LP, Lin JL, Hwang JJ.

In-vitro recording of adult zebrafish heart electrocardiogram – a platform for pharmacological testing.

Clin Chim Acta. 2011 Oct 9;412(21-22):1963-7. Epub 2011 Jul 8.
MiCAM ULTIMA Voltage Sensitive Dye

Lader JM, Vasquez C, Bao L, Maass K, Qu J, Kefalogianni E, Fishman GI, Coetzee WA, Morley GE.

Remodeling of atrial ATP-sensitive K+ channels in a model of salt-induced elevated blood pressure.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H964-74. Epub 2011 Jul 1.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Fedorov VV, Glukhov AV, Ambrosi CM, Kostecki G, Chang R, Janks D, Schuessler RB, Moazami N, Nichols CG, Efimov IR.

Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.

J Mol Cell Cardiol. 2011 Aug;51(2):215-25. Epub 2011 May 7.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Lou, Q., Li, W., Efimov, I. R.

Multiparametric Optical Mapping of the Langendorff-perfused Rabbit Heart (Video Article).

J. Vis. Exp. (55), e3160, DOI: 10.3791/3160 (2011)
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Lang, D., Sulkin, M., Lou, Q., Efimov, I. R.

Optical Mapping of Action Potentials and Calcium Transients in the Mouse Heart (Video Article).

J. Vis. Exp. (55), e3275, DOI: 10.3791/3275 (2011)
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Chua SK, Chang PC, Maruyama M, Turker I, Shinohara T, Shen MJ, Chen Z, Shen C, Rubart-von der Lohe M, Lopshire JC, Ogawa M, Weiss JN, Lin SF, Ai T, Chen PS.

Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles.

Circ Res. 2011 Apr 15;108(8):971-9. Epub 2011 Feb 24.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Maruyama M, Li BY, Chen H, Xu X, Song LS, Guatimosim S, Zhu W, Yong W, Zhang W, Bu G, Lin SF, Fishbein MC, Lederer WJ, Schild JH, Field LJ, Rubart M, Chen PS, Shou W.

FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice.

Circ Res. 2011 Apr 29;108(9):1042-52. Epub 2011 Mar 3.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Joung B, Park HW, Maruyama M, Tang L, Song J, Han S, Piccirillo G, Weiss JN, Lin SF, Chen PS.

Intracellular calcium and the mechanism of anodal supernormal excitability in langendorff perfused rabbit ventricles.

Circ J. 2011 Apr;75(4):834-43. Epub 2011 Feb 2.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Joung B, Zhang H, Shinohara T, Maruyama M, Han S, Kim D, Choi EK, On YK, Lin SF, Chen PS.

Delayed afterdepolarization in intact canine sinoatrial node as a novel mechanism for atrial arrhythmia.

J Cardiovasc Electrophysiol. 2011 Apr;22(4):448-54. doi: 10.1111/j.1540-8167.2010.01905.x. Epub 2010 Oct 6.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Maruyama M, Lin SF, Xie Y, Chua SK, Joung B, Han S, Shinohara T, Shen MJ, Qu Z, Weiss JN, Chen PS.

Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome.

Circ Arrhythm Electrophysiol. 2011 Feb;4(1):103-11. Epub 2010 Nov 15.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye & Calcium Sensitive Dye

Relan J, Pop M, Delingette H, Wright G, Ayache N, Sermesant M.

Personalisation of a Cardiac Electrophysiology Model using Optical Mapping and MRI for Prediction of Changes with Pacing.

IEEE Trans Biomed Eng. 2011 Jan 20. [Epub ahead of print]
MiCAM02-HR Dual Camera System Isolated Heart Voltage Sensitive Dye

Joung B, Chen PS, Lin SF.

The role of the calcium and the voltage clocks in sinoatrial node dysfunction.

Yonsei Med J. 2011 Mar 1;52(2):211-9.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Ding C, Everett TH 4th.

Assessment of cardiac conduction: basic principles of optical mapping.

Methods Mol Biol. 2010;660:239-52.
MiCAM ULTIMA MiCAM02-HR Isolated Heart Voltage Sensitive Dye

Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA.

PITX2c is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression.

Circ Cardiovasc Genet. 2011 Jan 31. [Epub ahead of print]
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Salama G, Akar FG.

Deciphering Arrhythmia Mechanisms: Tools of the Trade.

Cardiac Electrophysiology Clinics, Volume 3, Issue 1, Pages 11-21
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye

Askar SF, Ramkisoensing AA, Schalij MJ, Bingen BO, Swildens J, van der Laarse A, Atsma DE, de Vries AA, Ypey DL, Pijnappels DA.

Antiproliferative treatment of myofibroblasts prevents arrhythmias in vitro by limiting myofibroblast-induced depolarization.

Cardiovasc Res. 2011 Feb 2. [Epub ahead of print]
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye

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